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Murcko scaffold

Ring system with 2 rings and 10 atoms

37 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
37
With full pages
5
Scaffold SMILES

C1=NOC2(C1)CCNCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=NOC2(C1)CCNCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

3-Ethoxy-1-oxa-2,8-diazaspiro[4.5]dec-2-ene chemical structure, C9H16N2O2, CAS 130492-78-3
3-Ethoxy-1-oxa-2,8-diazaspiro[4.5]dec-2-ene
CAS 130492-78-3C9H16N2O2
8-[(tert-Butoxy)carbonyl]-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylic acid chemical structure, C13H20N2O5, CAS 479636-66-3
8-[(tert-Butoxy)carbonyl]-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylic acid
CAS 479636-66-3C13H20N2O5
3-Methoxy-8-methyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene chemical structure, C9H16N2O2, CAS 130492-93-2
3-Methoxy-8-methyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene
CAS 130492-93-2C9H16N2O2
tert-Butyl 3-methyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-8-carboxylate chemical structure, C13H22N2O3, CAS 1796557-44-2
tert-Butyl 3-methyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-8-carboxylate
CAS 1796557-44-2C13H22N2O3
3-Methyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene chemical structure, C8H14N2O, CAS 1781015-16-4
3-Methyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene
CAS 1781015-16-4C8H14N2O
3-Bromo-1-oxa-2,8-diazaspiro[4.5]dec-2-ene chemical structure, C7H11BrN2O, CAS 1282522-74-0
3-Bromo-1-oxa-2,8-diazaspiro[4.5]dec-2-ene
CAS 1282522-74-0C7H11BrN2O
tert-Butyl 3-bromo-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-8-carboxylate chemical structure, C12H19BrN2O3, CAS 1250999-79-1
tert-Butyl 3-bromo-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-8-carboxylate
CAS 1250999-79-1C12H19BrN2O3
8-tert-Butyl 3-ethyl 1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3,8-dicarboxylate chemical structure, C15H24N2O5, CAS 479636-65-2
8-tert-Butyl 3-ethyl 1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3,8-dicarboxylate
CAS 479636-65-2C15H24N2O5
8-Acetyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylic acid chemical structure, C10H14N2O4, CAS 2419914-86-4
8-Acetyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylic acid
CAS 2419914-86-4C10H14N2O4
1-Oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylic acid chemical structure, C8H12N2O3, CAS 1785578-57-5
1-Oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylic acid
CAS 1785578-57-5C8H12N2O3
8-Propyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylic acid chemical structure, C11H18N2O3, CAS 2649073-91-4
8-Propyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylic acid
CAS 2649073-91-4C11H18N2O3
Methyl 1-oxa-2,8-diazaspiro(4.5)dec-2-ene-3-carboxylate hydrochloride chemical structure, C9H15ClN2O3, CAS 1461707-94-7
Methyl 1-oxa-2,8-diazaspiro(4.5)dec-2-ene-3-carboxylate hydrochloride
CAS 1461707-94-7C9H15ClN2O3
Methyl 1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylate chemical structure, C9H14N2O3, CAS 1461869-05-5
Methyl 1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylate
CAS 1461869-05-5C9H14N2O3
1-Oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylic acid hydrochloride chemical structure, C8H13ClN2O3, CAS 1797976-77-2
1-Oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylic acid hydrochloride
CAS 1797976-77-2C8H13ClN2O3
3-Ethoxy-1-oxa-2,8-diazaspiro[4.5]dec-2-ene hydrochloride chemical structure, C9H17ClN2O2, CAS 1461714-76-0
3-Ethoxy-1-oxa-2,8-diazaspiro[4.5]dec-2-ene hydrochloride
CAS 1461714-76-0C9H17ClN2O2
N-Methyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxamide chemical structure, C9H15N3O2, CAS 2092560-96-6
N-Methyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxamide
CAS 2092560-96-6C9H15N3O2
N,N-Dimethyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-3-amine chemical structure, C9H17N3O, CAS 1422141-65-8
N,N-Dimethyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-3-amine
CAS 1422141-65-8C9H17N3O
3-Bromo-1-oxa-2,8-diazaspiro[4.5]dec-2-ene hydrochloride chemical structure, C7H12BrClN2O, CAS 2285440-56-2
3-Bromo-1-oxa-2,8-diazaspiro[4.5]dec-2-ene hydrochloride
CAS 2285440-56-2C7H12BrClN2O
3-(Trifluoromethyl)-1-oxa-2,8-diazaspiro(4.5)dec-2-ene chemical structure, C8H11F3N2O, CAS 2091398-00-2
3-(Trifluoromethyl)-1-oxa-2,8-diazaspiro(4.5)dec-2-ene
CAS 2091398-00-2C8H11F3N2O
Ethyl 1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylate chemical structure, C10H16N2O3, CAS 2091102-13-3
Ethyl 1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylate
CAS 2091102-13-3C10H16N2O3
3-Bromo-1-oxa-2,8-diazaspiro[4.5]dec-2-ene 2,2,2-trifluoroacetate chemical structure, C9H12BrF3N2O3, CAS 1256366-09-2
3-Bromo-1-oxa-2,8-diazaspiro[4.5]dec-2-ene 2,2,2-trifluoroacetate
CAS 1256366-09-2C9H12BrF3N2O3
tert-Butyl 3-formyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-8-carboxylate chemical structure, C13H20N2O4, CAS 2156656-88-9
tert-Butyl 3-formyl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-8-carboxylate
CAS 2156656-88-9C13H20N2O4
Alpibectir chemical structure, C12H14F6N2O2, CAS 2285440-39-1
Alpibectir
CAS 2285440-39-1C12H14F6N2O2
3-(Trifluoromethyl)-1-oxa-2,8-diazaspiro(4.5)dec-2-ene hydrochloride chemical structure, C8H12ClF3N2O, CAS 2285440-51-7
3-(Trifluoromethyl)-1-oxa-2,8-diazaspiro(4.5)dec-2-ene hydrochloride
CAS 2285440-51-7C8H12ClF3N2O