Fluorinated building blocks
- Chemicals
- 46,184
- Suppliers
- 2,155
About fluorinated building blocks
Fluorinated building blocks bring fluorine into a molecule, which can change potency, lipophilicity, metabolic stability and acidity. The group covers fluoroarenes and fluoropyridines, trifluoromethyl and difluoromethyl aromatics and heterocycles, trifluoromethoxy and pentafluorosulfanyl compounds, fluorinated alkyl chains, fluorinated amino acids and alcohols, and fluorinating reagents such as electrophilic N-F reagents, DAST type deoxofluorination reagents and trifluoromethylation reagents.
Read more about fluorinated building blocksShow less
About a fifth of modern drugs and an even larger share of new agrochemicals contain fluorine, so fluorinated building blocks are in constant demand. Late-stage fluorination is possible, but buying an already fluorinated building block is often simpler and cheaper.
Ask for purity by GC, HPLC and 19F NMR, isomeric purity, water and storage conditions. Some fluorinating reagents are hazardous, moisture sensitive or thermally unstable, so check handling guidance. Several regions are developing rules on per- and polyfluoroalkyl substances (PFAS), and definitions can cover compounds with a CF3 group, so check how the rules apply to your compound and use.
Top fluorinated building blocks
Showing 1 to 48 of 46,184 chemicals, most searched and traded first.
2-Fluoro-2-deoxy-D-glucoseCAS 29702-43-0C6H11FO571 suppliers
TegafurCAS 17902-23-7C8H9FN2O397 suppliers
Methyl 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-3-pyridinecarboxylateCAS 71145-03-4C16H15F3N2O471 suppliers
Midazolam maleateCAS 59467-94-6C22H17ClFN3O4Request quotes
Fenfluramine hydrochlorideCAS 404-82-0C12H17ClF3N29 suppliers
Niflumic acidCAS 4394-00-7C13H9F3N2O292 suppliers
2,2,2-TrifluoroethanolCAS 75-89-8C2H3F3O94 suppliers
Carbonyl cyanide p-trifluoromethoxyphenylhydrazoneCAS 370-86-5C10H5F3N4O76 suppliers
AstemizoleCAS 68844-77-9C28H31FN4O60 suppliers
Sb-202190CAS 152121-30-7C20H14FN3O61 suppliers
SparfloxacinCAS 110871-86-8C19H22F2N4O365 suppliers
Flunarizine hydrochlorideCAS 30484-77-6C26H28Cl2F2N254 suppliers
Paroxetine acetateCAS 72471-80-8C21H24FNO51 supplier
3-Fluoro-1,2-dihydroquinolin-2-oneCAS 124467-22-7C9H6FNO13 suppliers
EzogabineCAS 150812-12-7C16H18FN3O237 suppliers
Sb-203580CAS 152121-47-6C21H16FN3OS47 suppliers
FlumequineCAS 42835-25-6C14H12FNO358 suppliers
Perfluorooctanoyl chlorideCAS 335-64-8C8ClF15O16 suppliers
Lomefloxacin hydrochlorideCAS 98079-52-8C17H20ClF2N3O343 suppliers
CediranibCAS 288383-20-0C25H27FN4O344 suppliers
SorbinilCAS 68367-52-2C11H9FN2O36 suppliers
TriflupromazineCAS 146-54-3C18H19F3N2S5 suppliers
2-FluoropyrimidineCAS 31575-35-6C4H3FN229 suppliers
Flurazepam monohydrochlorideCAS 36105-20-1C21H24Cl2FN3ORequest quotes
FlupirtineCAS 56995-20-1C15H17FN4O216 suppliers
AlmitrineCAS 27469-53-0C26H29F2N75 suppliers
CarmofurCAS 61422-45-5C11H16FN3O325 suppliers
Ci-1040CAS 212631-79-3C17H14ClF2IN2O224 suppliers
Perfluorohexanesulfonic acidCAS 355-46-4C6HF13O3S11 suppliers
LumacaftorCAS 936727-05-8C24H18F2N2O534 suppliers
PerfluorooctaneCAS 307-34-6C8F1827 suppliers
Win 35428CAS 50370-56-4C16H20FNO25 suppliers
BuparlisibCAS 944396-07-0C18H21F3N6O230 suppliers
SarafloxacinCAS 98105-99-8C20H17F2N3O319 suppliers
ClinafloxacinCAS 105956-97-6C17H17ClFN3O318 suppliers
AtalurenCAS 775304-57-9C15H9FN2O335 suppliers
10H-Phenothiazine-10-propanamine, N,N-dimethyl-2-(trifluoromethyl)-, monohydrochlorideCAS 1098-60-8C18H20ClF3N2S9 suppliers
Xav-939CAS 284028-89-3C14H11F3N2OS23 suppliers
Ofloxacin hydrochlorideCAS 118120-51-7C18H21ClFN3O43 suppliers
BrequinarCAS 96187-53-0C23H15F2NO220 suppliers
Cisapride (USP/INN)CAS 104860-73-3C23H29ClFN3O49 suppliers
FlunarizineCAS 52468-60-7C26H26F2N221 suppliers
Rucaparib phosphateCAS 459868-92-9C19H21FN3O5P24 suppliers
NorfluoxetineCAS 83891-03-6C16H16F3NO9 suppliers
PerfluoropentaneCAS 678-26-2C5F127 suppliers
FluindioneCAS 957-56-2C15H9FO28 suppliers
GrepafloxacinCAS 119914-60-2C19H22FN3O35 suppliers
(+)-MefloquineCAS 51688-68-7C17H16F6N2O1 supplier
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Top suppliers of fluorinated building blocks
Manufacturers and traders with live products in this category. Paid members appear first.
TRC Finechems is a leading manufacturer and supplier of fine chemicals, intermediates, and APIs.
Fluorinated building blocks suppliers by country
Countries with at least 5 suppliers in this category. Open one to see its manufacturers and traders.
New fluorinated building blocks from suppliers
Products recently listed by manufacturers and traders in this category.
![5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile chemical structure, C14H8F2N4, CAS 1350653-26-7](/s/GPEUANAWZCBBHU-UHFFFAOYSA-N-200.webp)
Latest buy requests for fluorinated building blocks
Open requests from buyers. Suppliers can quote after signing in.
- 0 quotes2-Fluoro-2-deoxy-D-glucose1,000 kg+ 1 more products To Vietnam 7 d ago
- 0 quotesCarbonyl cyanide p-trifluoromethoxyphenylhydrazone1 kg To India 8 d ago
- 0 quotesMaltose50 MT+ 2 more products To NetherlandsMonthly need 8 d ago
- 1 quoteIbuprofen, sodium salt1 MT+ 2 more products To IndiaMonthly need 8 d ago
- 1 quoteAstemizole5 kg To India 8 d ago
- 1 quoteHistamine50 kg+ 1 more products To Bangladesh 8 d ago
Buyer names and contact details stay private until the buyer accepts a quote.
Guides for buyers
Practical reading on grades, documents, regulation and shipping before you buy.
- Guide · Chemical identityCAS registry numbers explained
What a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.
- Article · SourcingHow to write an RFQ that gets fast and accurate quotes
What suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.
- Guide · Trade and logisticsIncoterms 2020 for chemical buyers
The eleven Incoterms 2020 rules from a chemical buyer's point of view, with the traps around CIF insurance, FOB for containers, EXW exports, DDP imports and dangerous goods.
Frequently asked questions
Quick answers about buying fluorinated building blocks on CompoundList.
What are fluorinated building blocks?
Trifluoromethyl, difluoromethyl and fluoroaryl building blocks used to tune potency and metabolic stability.
How many fluorinated building blocks are listed on CompoundList?
CompoundList lists 46,184 chemicals in fluorinated building blocks. 2,155 suppliers offer products in this category.
Which fluorinated building blocks are the most popular?
The most searched and traded fluorinated building blocks on CompoundList include 2-Fluoro-2-deoxy-D-glucose, Tegafur, Methyl 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-3-pyridinecarboxylate, Midazolam maleate and Fenfluramine hydrochloride. They are part of the wider building blocks and research compounds family.
How do I buy fluorinated building blocks in bulk?
Open a chemical to compare its suppliers, or post one buy request with the product, grade, quantity and destination. Matching suppliers send you quotes, and your contact details stay private until you accept one.