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Subcategory of Building blocks and research compounds

Protected and unnatural amino acids

Boc, Fmoc and Cbz protected amino acids and non-proteinogenic amino acids for peptide synthesis and drug discovery.
Chemicals
2,942
Suppliers
590
Racks of small vials in a compound library
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About protected and unnatural amino acids

Protected and unnatural amino acids are the building blocks of peptide synthesis and peptidomimetic drug discovery. The group covers Fmoc, Boc and Cbz protected amino acids with side chain protection such as tBu, Trt, Pbf and Boc groups, amino acid esters and amides, N-methyl amino acids, D-amino acids, beta and gamma amino acids, alpha,alpha-disubstituted amino acids, and amino acids with unusual side chains such as fluorinated, cyclic or click-ready groups.

Read more about protected and unnatural amino acids

Solid phase peptide synthesis for research peptides and for peptide drugs uses Fmoc amino acids in large volumes, and the growth of peptide medicines has made high purity grades a major market. Unnatural amino acids help chemists improve stability, potency and selectivity of peptides and small molecules.

Ask for purity by HPLC, enantiomeric purity (often 99.5 percent or higher for GMP peptide synthesis), free amino acid content, dipeptide and beta-alanine impurities in Fmoc derivatives, acetate content, water and residual solvents. GMP grades with change control are needed for commercial peptide APIs. Store most protected amino acids cold and dry.

Top protected and unnatural amino acids

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Frequently asked questions

Quick answers about buying protected and unnatural amino acids on CompoundList.

What are protected and unnatural amino acids?

Boc, Fmoc and Cbz protected amino acids and non-proteinogenic amino acids for peptide synthesis and drug discovery.

How many protected and unnatural amino acids are listed on CompoundList?

CompoundList lists 2,942 chemicals in protected and unnatural amino acids. 590 suppliers offer products in this category.

Which protected and unnatural amino acids are the most popular?

The most searched and traded protected and unnatural amino acids on CompoundList include Pentagastrin, MG-132, Asunaprevir, Z-Devd-fmk and Boc-3,4-difluoro-L-phenylalanine. They are part of the wider building blocks and research compounds family.

How do I buy protected and unnatural amino acids in bulk?

Open a chemical to compare its suppliers, or post one buy request with the product, grade, quantity and destination. Matching suppliers send you quotes, and your contact details stay private until you accept one.

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Cannot find the protected and unnatural amino acids you need?

Post one buy request with the grade, quantity and destination. Matching suppliers send you quotes, and your contact details stay private until you accept one.