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Murcko scaffold

1,4-Dioxaspiro(4.5)dec-7-ene scaffold

60 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
60
With full pages
3
Scaffold SMILES

C1=CCC2(CC1)OCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4-Dioxaspiro(4.5)dec-7-ene page
Murcko scaffold C1=CCC2(CC1)OCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 60 chemicals

1,4-Dioxaspiro(4.5)dec-7-ene chemical structure, C8H12O2, CAS 7092-24-2
1,4-Dioxaspiro(4.5)dec-7-ene
CAS 7092-24-2C8H12O2
1,4-Dioxaspiro[4.5]dec-7-ene-7-carbaldehyde chemical structure, C9H12O3, CAS 63517-54-4
1,4-Dioxaspiro[4.5]dec-7-ene-7-carbaldehyde
CAS 63517-54-4C9H12O3
7-Methyl-1,4-dioxaspiro[4.5]dec-7-ene-8-carbaldehyde chemical structure, C10H14O3, CAS 29915-83-1
7-Methyl-1,4-dioxaspiro[4.5]dec-7-ene-8-carbaldehyde
CAS 29915-83-1C10H14O3
1,4-Dioxaspiro[4.5]dec-7-ene, 8-ethenyl-7-methyl- chemical structure, C11H16O2, CAS 89654-02-4
1,4-Dioxaspiro[4.5]dec-7-ene, 8-ethenyl-7-methyl-
CAS 89654-02-4C11H16O2
1,4-Dioxaspiro[4.5]dec-7-ene, 8-ethenyl- chemical structure, C10H14O2, CAS 57707-02-5
1,4-Dioxaspiro[4.5]dec-7-ene, 8-ethenyl-
CAS 57707-02-5C10H14O2
1,4-Dioxaspiro[4.5]dec-7-ene, 7,9,9-trimethyl- chemical structure, C11H18O2, CAS 65339-06-2
1,4-Dioxaspiro[4.5]dec-7-ene, 7,9,9-trimethyl-
CAS 65339-06-2C11H18O2
1,4-Dioxaspiro[4.5]dec-7-ene-8-methanol, 7,9,9-trimethyl- chemical structure, C12H20O3, CAS 23069-07-0
1,4-Dioxaspiro[4.5]dec-7-ene-8-methanol, 7,9,9-trimethyl-
CAS 23069-07-0C12H20O3
8-[(Trifluoromethylsulfonyl)oxy]-1,4-dioxaspiro[4.5]deca-7-ene-7-carboxylic acid methyl ester chemical structure, C11H13F3O7S, CAS 168423-42-5
8-[(Trifluoromethylsulfonyl)oxy]-1,4-dioxaspiro[4.5]deca-7-ene-7-carboxylic acid methyl ester
CAS 168423-42-5C11H13F3O7S
1,4-Dioxaspiro[4.5]dec-7-en-8-ylmethanol chemical structure, C9H14O3, CAS 72445-21-7
1,4-Dioxaspiro[4.5]dec-7-en-8-ylmethanol
CAS 72445-21-7C9H14O3
1,4-Dioxaspiro[4.5]dec-7-ene-8-carbonyl azide, 7-methyl- chemical structure, C10H13N3O3, CAS 222625-92-5
1,4-Dioxaspiro[4.5]dec-7-ene-8-carbonyl azide, 7-methyl-
CAS 222625-92-5C10H13N3O3
2-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)acetic acid chemical structure, C10H14O4, CAS 33082-77-8
2-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)acetic acid
CAS 33082-77-8C10H14O4
1,4-Dioxaspiro[4.5]dec-7-en-8-yl trifluoromethanesulfonate chemical structure, C9H11F3O5S, CAS 170011-47-9
1,4-Dioxaspiro[4.5]dec-7-en-8-yl trifluoromethanesulfonate
CAS 170011-47-9C9H11F3O5S
Ethyl 7-methyl-1,4-dioxaspiro[4.5]dec-7-ene-8-carboxylate chemical structure, C12H18O4, CAS 32917-26-3
Ethyl 7-methyl-1,4-dioxaspiro[4.5]dec-7-ene-8-carboxylate
CAS 32917-26-3C12H18O4
Methyl 1,4-dioxaspiro[4.5]dec-7-ene-8-carboxylate chemical structure, C10H14O4, CAS 54584-38-2
Methyl 1,4-dioxaspiro[4.5]dec-7-ene-8-carboxylate
CAS 54584-38-2C10H14O4
7-Bromo-1,4-dioxaspiro[4.5]dec-7-ene chemical structure, C8H11BrO2, CAS 81036-84-2
7-Bromo-1,4-dioxaspiro[4.5]dec-7-ene
CAS 81036-84-2C8H11BrO2
Methyl 1,4-dioxaspiro[4.5]dec-7-ene-7-carboxylate chemical structure, C10H14O4, CAS 79678-14-1
Methyl 1,4-dioxaspiro[4.5]dec-7-ene-7-carboxylate
CAS 79678-14-1C10H14O4
7-Bromo-9,9-dimethyl-1,4-dioxaspiro[4.5]dec-7-ene chemical structure, C10H15BrO2, CAS 81036-85-3
7-Bromo-9,9-dimethyl-1,4-dioxaspiro[4.5]dec-7-ene
CAS 81036-85-3C10H15BrO2
8-(Prop-2-en-1-yl)-1,4-dioxaspiro[4.5]dec-7-ene chemical structure, C11H16O2, CAS 81842-00-4
8-(Prop-2-en-1-yl)-1,4-dioxaspiro[4.5]dec-7-ene
CAS 81842-00-4C11H16O2
8-(3-Methylbut-2-en-1-yl)-1,4-dioxaspiro[4.5]dec-7-ene chemical structure, C13H20O2, CAS 81842-01-5
8-(3-Methylbut-2-en-1-yl)-1,4-dioxaspiro[4.5]dec-7-ene
CAS 81842-01-5C13H20O2
Ethyl 5-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)pentanoate chemical structure, C15H24O4, CAS 81842-07-1
Ethyl 5-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)pentanoate
CAS 81842-07-1C15H24O4
8-(6-Methylhept-5-EN-2-yl)-1,4-dioxaspiro[4.5]dec-7-ene chemical structure, C16H26O2, CAS 87640-91-3
8-(6-Methylhept-5-EN-2-yl)-1,4-dioxaspiro[4.5]dec-7-ene
CAS 87640-91-3C16H26O2
7-Methyl-1,4-dioxaspiro[4.5]dec-7-ene chemical structure, C9H14O2, CAS 83313-55-7
7-Methyl-1,4-dioxaspiro[4.5]dec-7-ene
CAS 83313-55-7C9H14O2
6-Methyl-6-(prop-2-en-1-yl)-1,4-dioxaspiro[4.5]dec-7-ene chemical structure, C12H18O2, CAS 89654-03-5
6-Methyl-6-(prop-2-en-1-yl)-1,4-dioxaspiro[4.5]dec-7-ene
CAS 89654-03-5C12H18O2
1,4-Dioxaspiro[4.5]dec-7-ene-8-carboxylic acid chemical structure, C9H12O4, CAS 92525-59-2
1,4-Dioxaspiro[4.5]dec-7-ene-8-carboxylic acid
CAS 92525-59-2C9H12O4