CompoundList
Sign in
Murcko scaffold

1-{1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}piperidine scaffold

44 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
44
With full pages
13
Scaffold SMILES

c1ccc(-n2ncc3c(N4CCCCC4)ncnc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-{1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}piperidine page
Murcko scaffold c1ccc(-n2ncc3c(N4CCCCC4)ncnc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 44 of 44 chemicals

6-Methyl-1-(4-nitrophenyl)-4-(piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C17H18N6O2, CAS 5346-45-2
6-Methyl-1-(4-nitrophenyl)-4-(piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine
CAS 5346-45-2C17H18N6O2
Ethyl 1-[1-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-yl]piperidine-4-carboxylate chemical structure, C19H20ClN5O2, CAS 393845-36-8
Ethyl 1-[1-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-yl]piperidine-4-carboxylate
CAS 393845-36-8C19H20ClN5O2
1-[1-(2,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]piperidine-4-carboxamide chemical structure, C19H22N6O, CAS 393845-48-2
1-[1-(2,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]piperidine-4-carboxamide
CAS 393845-48-2C19H22N6O
1-{1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}piperidine chemical structure, C16H17N5, CAS 23000-46-6
1-{1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}piperidine
CAS 23000-46-6C16H17N5
1-(1-Phenylpyrazolo[3,4-d]pyrimidin-4-yl)piperidine-4-carboxamide chemical structure, C17H18N6O, CAS 393845-44-8
1-(1-Phenylpyrazolo[3,4-d]pyrimidin-4-yl)piperidine-4-carboxamide
CAS 393845-44-8C17H18N6O
1-(4-Chlorophenyl)-4-(4-methylpiperidin-1-yl)pyrazolo[3,4-d]pyrimidine chemical structure, C17H18ClN5, CAS 393845-26-6
1-(4-Chlorophenyl)-4-(4-methylpiperidin-1-yl)pyrazolo[3,4-d]pyrimidine
CAS 393845-26-6C17H18ClN5
1-[1-(3-Methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]piperidine-4-carboxamide chemical structure, C18H20N6O, CAS 393845-47-1
1-[1-(3-Methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]piperidine-4-carboxamide
CAS 393845-47-1C18H20N6O
4-(4-Methylpiperidin-1-yl)-1-phenylpyrazolo[3,4-d]pyrimidine chemical structure, C17H19N5, CAS 393845-25-5
4-(4-Methylpiperidin-1-yl)-1-phenylpyrazolo[3,4-d]pyrimidine
CAS 393845-25-5C17H19N5
1-(2,4-Dimethylphenyl)-4-(4-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C19H23N5, CAS 393845-29-9
1-(2,4-Dimethylphenyl)-4-(4-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine
CAS 393845-29-9C19H23N5
Ethyl 1-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperidine-4-carboxylate chemical structure, C19H21N5O2, CAS 393845-35-7
Ethyl 1-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperidine-4-carboxylate
CAS 393845-35-7C19H21N5O2
1-(1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperidine-4-carboxamide chemical structure, C17H17ClN6O, CAS 393845-45-9
1-(1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperidine-4-carboxamide
CAS 393845-45-9C17H17ClN6O
6-Methylsulfanyl-1-phenyl-4-piperidin-1-ylpyrazolo[3,4-d]pyrimidine chemical structure, C17H19N5S, CAS 339106-39-7
6-Methylsulfanyl-1-phenyl-4-piperidin-1-ylpyrazolo[3,4-d]pyrimidine
CAS 339106-39-7C17H19N5S
1-(4-Methylphenyl)-6-(methylsulfanyl)-4-piperidino-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C18H21N5S, CAS 339106-50-2
1-(4-Methylphenyl)-6-(methylsulfanyl)-4-piperidino-1H-pyrazolo[3,4-d]pyrimidine
CAS 339106-50-2C18H21N5S
Ethyl 1-[1-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]piperidine-4-carboxylate chemical structure, C20H23N5O2, CAS 393845-38-0
Ethyl 1-[1-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]piperidine-4-carboxylate
CAS 393845-38-0C20H23N5O2
Ethyl 1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]piperidine-3-carboxylate chemical structure, C19H20ClN5O2, CAS 393845-41-5
Ethyl 1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]piperidine-3-carboxylate
CAS 393845-41-5C19H20ClN5O2
4-(3-Methylpiperidin-1-yl)-1-(m-tolyl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C18H21N5, CAS 393845-23-3
4-(3-Methylpiperidin-1-yl)-1-(m-tolyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS 393845-23-3C18H21N5
1-(2,4-Dimethylphenyl)-4-(3-methylpiperidin-1-yl)pyrazolo[4,5-e]pyrimidine chemical structure, C19H23N5, CAS 393845-24-4
1-(2,4-Dimethylphenyl)-4-(3-methylpiperidin-1-yl)pyrazolo[4,5-e]pyrimidine
CAS 393845-24-4C19H23N5
1-(4-Chlorophenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C17H18ClN5, CAS 393845-21-1
1-(4-Chlorophenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine
CAS 393845-21-1C17H18ClN5
4-(3-Methylpiperidin-1-yl)-1-phenylpyrazolo[3,4-d]pyrimidine chemical structure, C17H19N5, CAS 393845-20-0
4-(3-Methylpiperidin-1-yl)-1-phenylpyrazolo[3,4-d]pyrimidine
CAS 393845-20-0C17H19N5
1-(2,4-Dimethylphenyl)-4-(3,5-dimethylpiperidyl)pyrazolo[5,4-d]pyrimidine chemical structure, C20H25N5, CAS 393823-04-6
1-(2,4-Dimethylphenyl)-4-(3,5-dimethylpiperidyl)pyrazolo[5,4-d]pyrimidine
CAS 393823-04-6C20H25N5
1-[1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-N,N-diethylpiperidine-3-carboxamide chemical structure, C21H25ClN6O, CAS 393845-16-4
1-[1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-N,N-diethylpiperidine-3-carboxamide
CAS 393845-16-4C21H25ClN6O
1-(1-(3-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperidine-4-carboxamide chemical structure, C17H17ClN6O, CAS 890949-60-7
1-(1-(3-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperidine-4-carboxamide
CAS 890949-60-7C17H17ClN6O
1-[1-(4-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-3,5-dimethylpiperidine chemical structure, C18H20FN5, CAS 890881-34-2
1-[1-(4-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-3,5-dimethylpiperidine
CAS 890881-34-2C18H20FN5
1-(3-Chlorophenyl)-4-(3,5-dimethylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C18H20ClN5, CAS 890947-50-9
1-(3-Chlorophenyl)-4-(3,5-dimethylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine
CAS 890947-50-9C18H20ClN5