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Murcko scaffold

3-Phenyl-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine scaffold

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
9
With full pages
2
Scaffold SMILES

c1ccc(-c2cnn3c(-c4ccncc4)ccnc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenyl-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine page
Murcko scaffold c1ccc(-c2cnn3c(-c4ccncc4)ccnc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

3-(4-Fluorophenyl)-7-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine chemical structure, C17H11FN4, CAS 861209-71-4
3-(4-Fluorophenyl)-7-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine
CAS 861209-71-4C17H11FN4
3-(4-Chlorophenyl)-7-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine chemical structure, C17H11ClN4, CAS 861209-73-6
3-(4-Chlorophenyl)-7-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine
CAS 861209-73-6C17H11ClN4
4-{2-Methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl}pyridine chemical structure, C18H14N4, CAS 1087644-77-6
4-{2-Methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl}pyridine
CAS 1087644-77-6C18H14N4
3-(3-Chlorophenyl)-2-(methoxymethyl)-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C19H15ClN4O, CAS 1332105-86-8
3-(3-Chlorophenyl)-2-(methoxymethyl)-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CAS 1332105-86-8C19H15ClN4O
2-(Methoxymethyl)-3-phenyl-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C19H16N4O, CAS 1324078-60-5
2-(Methoxymethyl)-3-phenyl-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CAS 1324078-60-5C19H16N4O
3-(4-Chlorophenyl)-2-(methoxymethyl)-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C19H15ClN4O, CAS 1332098-54-0
3-(4-Chlorophenyl)-2-(methoxymethyl)-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CAS 1332098-54-0C19H15ClN4O
3-Phenyl-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C17H12N4, CAS 1332071-12-1
3-Phenyl-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CAS 1332071-12-1C17H12N4
3-(4-Fluorophenyl)-2-(methoxymethyl)-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C19H15FN4O, CAS 1324088-15-4
3-(4-Fluorophenyl)-2-(methoxymethyl)-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CAS 1324088-15-4C19H15FN4O
3-(3-Chlorophenyl)-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C17H11ClN4, CAS 1351256-20-6
3-(3-Chlorophenyl)-7-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CAS 1351256-20-6C17H11ClN4