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Murcko scaffold

Ring system with 4 rings and 21 atoms

53 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
53
With full pages
5
Scaffold SMILES

c1ccc(-c2cnn3c(N4CCCCC4)ccnc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2cnn3c(N4CCCCC4)ccnc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 53 chemicals

5-Methyl-7-(4-methylpiperidin-1-yl)-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C19H22N4, CAS 849914-04-1
5-Methyl-7-(4-methylpiperidin-1-yl)-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 849914-04-1C19H22N4
2,5-Dimethyl-3-phenyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C19H22N4, CAS 850801-06-8
2,5-Dimethyl-3-phenyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine
CAS 850801-06-8C19H22N4
5-Methyl-3-phenyl-7-piperidin-1-ylpyrazolo[1,5-a]pyrimidine chemical structure, C18H20N4, CAS 877787-00-3
5-Methyl-3-phenyl-7-piperidin-1-ylpyrazolo[1,5-a]pyrimidine
CAS 877787-00-3C18H20N4
2,5-Dimethyl-7-(4-methylpiperidin-1-yl)-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C20H24N4, CAS 877621-97-1
2,5-Dimethyl-7-(4-methylpiperidin-1-yl)-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 877621-97-1C20H24N4
3-(4-Chlorophenyl)-5-methyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C18H19ClN4, CAS 899407-59-1
3-(4-Chlorophenyl)-5-methyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine
CAS 899407-59-1C18H19ClN4
5-Isopropyl-2-methyl-3-phenyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C21H26N4, CAS 896812-72-9
5-Isopropyl-2-methyl-3-phenyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine
CAS 896812-72-9C21H26N4
5-(tert-Butyl)-3-phenyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C21H26N4, CAS 896826-60-1
5-(tert-Butyl)-3-phenyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine
CAS 896826-60-1C21H26N4
5-tert-Butyl-3-(4-chlorophenyl)-7-(4-methylpiperidin-1-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C22H27ClN4, CAS 896827-52-4
5-tert-Butyl-3-(4-chlorophenyl)-7-(4-methylpiperidin-1-yl)pyrazolo[1,5-a]pyrimidine
CAS 896827-52-4C22H27ClN4
6-Ethyl-2,5-dimethyl-7-(4-methylpiperidin-1-yl)-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C22H28N4, CAS 896846-74-5
6-Ethyl-2,5-dimethyl-7-(4-methylpiperidin-1-yl)-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 896846-74-5C22H28N4
6-Ethyl-2,5-dimethyl-3-phenyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C21H26N4, CAS 899395-72-3
6-Ethyl-2,5-dimethyl-3-phenyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine
CAS 899395-72-3C21H26N4
5-tert-Butyl-7-(4-methylpiperidin-1-yl)-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C22H28N4, CAS 899384-73-7
5-tert-Butyl-7-(4-methylpiperidin-1-yl)-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 899384-73-7C22H28N4
2-Methyl-3-phenyl-7-(piperidin-1-yl)-5-propylpyrazolo[1,5-a]pyrimidine chemical structure, C21H26N4, CAS 900259-72-5
2-Methyl-3-phenyl-7-(piperidin-1-yl)-5-propylpyrazolo[1,5-a]pyrimidine
CAS 900259-72-5C21H26N4
3-(4-Chlorophenyl)-5-methyl-7-(4-methylpiperidin-1-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C19H21ClN4, CAS 900291-23-8
3-(4-Chlorophenyl)-5-methyl-7-(4-methylpiperidin-1-yl)pyrazolo[1,5-a]pyrimidine
CAS 900291-23-8C19H21ClN4
5-Isopropyl-2-methyl-7-(4-methylpiperidin-1-yl)-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C22H28N4, CAS 896804-02-7
5-Isopropyl-2-methyl-7-(4-methylpiperidin-1-yl)-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 896804-02-7C22H28N4
5-tert-Butyl-2-methyl-7-(4-methylpiperidin-1-yl)-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C23H30N4, CAS 877781-06-1
5-tert-Butyl-2-methyl-7-(4-methylpiperidin-1-yl)-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 877781-06-1C23H30N4
3-(2-Methoxyphenyl)-2,5-dimethyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C20H24N4O, CAS 879580-00-4
3-(2-Methoxyphenyl)-2,5-dimethyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine
CAS 879580-00-4C20H24N4O
5-tert-Butyl-3-(4-chlorophenyl)-7-(3,5-dimethylpiperidin-1-yl)-2-methylpyrazolo[1,5-a]pyrimidine chemical structure, C24H31ClN4, CAS 877809-95-5
5-tert-Butyl-3-(4-chlorophenyl)-7-(3,5-dimethylpiperidin-1-yl)-2-methylpyrazolo[1,5-a]pyrimidine
CAS 877809-95-5C24H31ClN4
7-(3,5-Dimethylpiperidin-1-yl)-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C20H24N4, CAS 850731-61-2
7-(3,5-Dimethylpiperidin-1-yl)-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 850731-61-2C20H24N4
3-(4-Chlorophenyl)-2,5-dimethyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C19H21ClN4, CAS 877802-18-1
3-(4-Chlorophenyl)-2,5-dimethyl-7-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidine
CAS 877802-18-1C19H21ClN4
3-(4-Chlorophenyl)-7-(3,5-dimethylpiperidin-1-yl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine chemical structure, C21H25ClN4, CAS 849828-67-7
3-(4-Chlorophenyl)-7-(3,5-dimethylpiperidin-1-yl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine
CAS 849828-67-7C21H25ClN4
3-(4-Chlorophenyl)-2,5-dimethyl-7-(4-methylpiperidin-1-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C20H23ClN4, CAS 877790-55-1
3-(4-Chlorophenyl)-2,5-dimethyl-7-(4-methylpiperidin-1-yl)pyrazolo[1,5-a]pyrimidine
CAS 877790-55-1C20H23ClN4
5-tert-Butyl-7-(3,5-dimethylpiperidin-1-yl)-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C24H32N4, CAS 850824-91-8
5-tert-Butyl-7-(3,5-dimethylpiperidin-1-yl)-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 850824-91-8C24H32N4
7-(3,5-Dimethylpiperidin-1-yl)-2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidine chemical structure, C21H26N4, CAS 877805-04-4
7-(3,5-Dimethylpiperidin-1-yl)-2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidine
CAS 877805-04-4C21H26N4
5-tert-Butyl-2-methyl-3-phenyl-7-piperidin-1-ylpyrazolo[1,5-a]pyrimidine chemical structure, C22H28N4, CAS 849910-44-7
5-tert-Butyl-2-methyl-3-phenyl-7-piperidin-1-ylpyrazolo[1,5-a]pyrimidine
CAS 849910-44-7C22H28N4