CompoundList
Sign in
Murcko scaffold

1-(Phenoxyacetyl)-4-(phenylsulfonyl)piperazine scaffold

42 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
42
With full pages
7
Scaffold SMILES

O=C(COc1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Phenoxyacetyl)-4-(phenylsulfonyl)piperazine page
Murcko scaffold O=C(COc1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

1-[4-(4-Chlorophenyl)sulfonylpiperazin-1-yl]-2-(4-methoxyphenoxy)ethanone chemical structure, C19H21ClN2O5S, CAS 423740-24-3
1-[4-(4-Chlorophenyl)sulfonylpiperazin-1-yl]-2-(4-methoxyphenoxy)ethanone
CAS 423740-24-3C19H21ClN2O5S
1-[4-(4-Chlorophenyl)sulfonylpiperazin-1-yl]-2-(3-methylphenoxy)ethanone chemical structure, C19H21ClN2O4S, CAS 423735-76-6
1-[4-(4-Chlorophenyl)sulfonylpiperazin-1-yl]-2-(3-methylphenoxy)ethanone
CAS 423735-76-6C19H21ClN2O4S
1-[4-(4-Chlorophenyl)sulfonylpiperazin-1-yl]-2-phenoxyethanone chemical structure, C18H19ClN2O4S, CAS 522650-45-9
1-[4-(4-Chlorophenyl)sulfonylpiperazin-1-yl]-2-phenoxyethanone
CAS 522650-45-9C18H19ClN2O4S
2-(4-Methylphenoxy)-1-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]ethanone chemical structure, C20H24N2O4S, CAS 423740-22-1
2-(4-Methylphenoxy)-1-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]ethanone
CAS 423740-22-1C20H24N2O4S
1-[4-(4-Methoxy-benzenesulfonyl)-piperazin-1-yl]-2-phenoxy-ethanone chemical structure, C19H22N2O5S, CAS 5975-52-0
1-[4-(4-Methoxy-benzenesulfonyl)-piperazin-1-yl]-2-phenoxy-ethanone
CAS 5975-52-0C19H22N2O5S
1-(Phenoxyacetyl)-4-(phenylsulfonyl)piperazine chemical structure, C18H20N2O4S, CAS 333756-50-6
1-(Phenoxyacetyl)-4-(phenylsulfonyl)piperazine
CAS 333756-50-6C18H20N2O4S
1-[4-(4-Methylbenzene-1-sulfonyl)piperazin-1-yl]-2-phenoxyethan-1-one chemical structure, C19H22N2O4S, CAS 5937-06-4
1-[4-(4-Methylbenzene-1-sulfonyl)piperazin-1-yl]-2-phenoxyethan-1-one
CAS 5937-06-4C19H22N2O4S
2-(4-Chlorophenoxy)-1-{4-[(4-methylphenyl)sulfonyl]piperazin-1-yl}ethanone chemical structure, C19H21ClN2O4S, CAS 333757-43-0
2-(4-Chlorophenoxy)-1-{4-[(4-methylphenyl)sulfonyl]piperazin-1-yl}ethanone
CAS 333757-43-0C19H21ClN2O4S
1-[(4-Chlorophenoxy)acetyl]-4-[(4-methoxyphenyl)sulfonyl]piperazine chemical structure, C19H21ClN2O5S, CAS 333757-59-8
1-[(4-Chlorophenoxy)acetyl]-4-[(4-methoxyphenyl)sulfonyl]piperazine
CAS 333757-59-8C19H21ClN2O5S
2-(4-Methylphenoxy)-1-[4-(4-nitrophenyl)sulfonylpiperazin-1-yl]ethanone chemical structure, C19H21N3O6S, CAS 519005-69-7
2-(4-Methylphenoxy)-1-[4-(4-nitrophenyl)sulfonylpiperazin-1-yl]ethanone
CAS 519005-69-7C19H21N3O6S
2-(3-Methylphenoxy)-1-[4-(4-nitrophenyl)sulfonylpiperazin-1-yl]ethanone chemical structure, C19H21N3O6S, CAS 428837-95-0
2-(3-Methylphenoxy)-1-[4-(4-nitrophenyl)sulfonylpiperazin-1-yl]ethanone
CAS 428837-95-0C19H21N3O6S
1-{4-[(4-Fluorophenyl)sulfonyl]piperazin-1-yl}-2-phenoxyethanone chemical structure, C18H19FN2O4S, CAS 441745-94-4
1-{4-[(4-Fluorophenyl)sulfonyl]piperazin-1-yl}-2-phenoxyethanone
CAS 441745-94-4C18H19FN2O4S
1-[4-(4-Fluorophenyl)sulfonylpiperazin-1-yl]-2-(4-methoxyphenoxy)ethanone chemical structure, C19H21FN2O5S, CAS 428847-62-5
1-[4-(4-Fluorophenyl)sulfonylpiperazin-1-yl]-2-(4-methoxyphenoxy)ethanone
CAS 428847-62-5C19H21FN2O5S
1-[4-(4-Fluorophenyl)sulfonylpiperazin-1-yl]-2-(4-methylphenoxy)ethanone chemical structure, C19H21FN2O4S, CAS 428503-13-3
1-[4-(4-Fluorophenyl)sulfonylpiperazin-1-yl]-2-(4-methylphenoxy)ethanone
CAS 428503-13-3C19H21FN2O4S
1-[4-(4-Fluorophenyl)sulfonylpiperazin-1-yl]-2-(3-methylphenoxy)ethanone chemical structure, C19H21FN2O4S, CAS 428837-67-6
1-[4-(4-Fluorophenyl)sulfonylpiperazin-1-yl]-2-(3-methylphenoxy)ethanone
CAS 428837-67-6C19H21FN2O4S
2-(4-Chlorophenoxy)-1-[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]ethanone chemical structure, C18H18ClFN2O4S, CAS 428850-79-7
2-(4-Chlorophenoxy)-1-[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]ethanone
CAS 428850-79-7C18H18ClFN2O4S
N-[4-[4-[2-(4-Methoxyphenoxy)acetyl]piperazin-1-yl]sulfonylphenyl]acetamide chemical structure, C21H25N3O6S, CAS 428834-83-7
N-[4-[4-[2-(4-Methoxyphenoxy)acetyl]piperazin-1-yl]sulfonylphenyl]acetamide
CAS 428834-83-7C21H25N3O6S
N-[4-[4-[2-(4-Methylphenoxy)acetyl]piperazin-1-yl]sulfonylphenyl]acetamide chemical structure, C21H25N3O5S, CAS 428845-96-9
N-[4-[4-[2-(4-Methylphenoxy)acetyl]piperazin-1-yl]sulfonylphenyl]acetamide
CAS 428845-96-9C21H25N3O5S
N-[4-[4-[2-(3-Methylphenoxy)acetyl]piperazin-1-yl]sulfonylphenyl]acetamide chemical structure, C21H25N3O5S, CAS 428853-70-7
N-[4-[4-[2-(3-Methylphenoxy)acetyl]piperazin-1-yl]sulfonylphenyl]acetamide
CAS 428853-70-7C21H25N3O5S
N-[4-[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]sulfonylphenyl]acetamide chemical structure, C20H22ClN3O5S, CAS 428829-07-6
N-[4-[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]sulfonylphenyl]acetamide
CAS 428829-07-6C20H22ClN3O5S
N-[4-[4-[2-(4-Bromophenoxy)acetyl]piperazin-1-yl]sulfonylphenyl]acetamide chemical structure, C20H22BrN3O5S, CAS 428837-61-0
N-[4-[4-[2-(4-Bromophenoxy)acetyl]piperazin-1-yl]sulfonylphenyl]acetamide
CAS 428837-61-0C20H22BrN3O5S
1-[4-(4-Fluorophenyl)sulfonylpiperazin-1-yl]-2-(3-methyl-4-nitrophenoxy)ethanone chemical structure, C19H20FN3O6S, CAS 717860-05-4
1-[4-(4-Fluorophenyl)sulfonylpiperazin-1-yl]-2-(3-methyl-4-nitrophenoxy)ethanone
CAS 717860-05-4C19H20FN3O6S
2-(4-Methoxyphenoxy)-1-[4-(2-nitrophenyl)sulfonylpiperazin-1-yl]ethanone chemical structure, C19H21N3O7S, CAS 500271-98-7
2-(4-Methoxyphenoxy)-1-[4-(2-nitrophenyl)sulfonylpiperazin-1-yl]ethanone
CAS 500271-98-7C19H21N3O7S
2-(4-Methylphenoxy)-1-[4-(2-nitrophenyl)sulfonylpiperazin-1-yl]ethanone chemical structure, C19H21N3O6S, CAS 428844-20-6
2-(4-Methylphenoxy)-1-[4-(2-nitrophenyl)sulfonylpiperazin-1-yl]ethanone
CAS 428844-20-6C19H21N3O6S