CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 23 atoms

28 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
28
With full pages
6
Scaffold SMILES

O=C(Nc1ccccc1)Nc1ccc(Oc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)Nc1ccc(Oc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

1-(4-Chlorophenyl)-3-(4-phenoxyphenyl)urea chemical structure, C19H15ClN2O2, CAS 167634-42-6
1-(4-Chlorophenyl)-3-(4-phenoxyphenyl)urea
CAS 167634-42-6C19H15ClN2O2
N-(3-Chlorophenyl)-N'-(4-phenoxyphenyl)urea chemical structure, C19H15ClN2O2, CAS 178607-15-3
N-(3-Chlorophenyl)-N'-(4-phenoxyphenyl)urea
CAS 178607-15-3C19H15ClN2O2
1-(2,4-Difluorophenyl)-3-(4-phenoxyphenyl)urea chemical structure, C19H14F2N2O2, CAS 701927-64-2
1-(2,4-Difluorophenyl)-3-(4-phenoxyphenyl)urea
CAS 701927-64-2C19H14F2N2O2
1-(2-Chloro-4,5-difluorophenyl)-3-(4-phenoxyphenyl)urea chemical structure, C19H13ClF2N2O2, CAS 328016-33-7
1-(2-Chloro-4,5-difluorophenyl)-3-(4-phenoxyphenyl)urea
CAS 328016-33-7C19H13ClF2N2O2
1-(3,4-Dimethoxyphenyl)-3-(4-phenoxyphenyl)urea chemical structure, C21H20N2O4, CAS 362593-82-6
1-(3,4-Dimethoxyphenyl)-3-(4-phenoxyphenyl)urea
CAS 362593-82-6C21H20N2O4
1-(3-Methoxyphenyl)-3-(4-phenoxyphenyl)urea chemical structure, C20H18N2O3, CAS 701948-99-4
1-(3-Methoxyphenyl)-3-(4-phenoxyphenyl)urea
CAS 701948-99-4C20H18N2O3
1-(2,4-Dimethoxyphenyl)-3-(4-phenoxyphenyl)urea chemical structure, C21H20N2O4, CAS 708228-29-9
1-(2,4-Dimethoxyphenyl)-3-(4-phenoxyphenyl)urea
CAS 708228-29-9C21H20N2O4
Methyl 2-(4-{[(4-chloroanilino)carbonyl]amino}phenoxy)benzenecarboxylate chemical structure, C21H17ClN2O4, CAS 865660-46-4
Methyl 2-(4-{[(4-chloroanilino)carbonyl]amino}phenoxy)benzenecarboxylate
CAS 865660-46-4C21H17ClN2O4
Methyl 2-{[(4-phenoxyphenyl)carbamoyl]amino}benzoate chemical structure, C21H18N2O4, CAS 708218-77-3
Methyl 2-{[(4-phenoxyphenyl)carbamoyl]amino}benzoate
CAS 708218-77-3C21H18N2O4
N-(4-Phenoxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea chemical structure, C20H15F3N2O2, CAS 618443-83-7
N-(4-Phenoxyphenyl)-N'-(3-(trifluoromethyl)phenyl)urea
CAS 618443-83-7C20H15F3N2O2
N-(3,4-Dichlorophenyl)-N'-(4-phenoxyphenyl)urea chemical structure, C19H14Cl2N2O2, CAS 178607-18-6
N-(3,4-Dichlorophenyl)-N'-(4-phenoxyphenyl)urea
CAS 178607-18-6C19H14Cl2N2O2
1-(4-(3-(Methylcarbamoyl)phenoxy)phenyl)-3-(5-tert-butyl-2-methoxyphenyl)urea chemical structure, C26H29N3O4, CAS 284461-36-5
1-(4-(3-(Methylcarbamoyl)phenoxy)phenyl)-3-(5-tert-butyl-2-methoxyphenyl)urea
CAS 284461-36-5C26H29N3O4
1-(4-(3-(Methylcarbamoyl)-4-methoxyphenoxy)phenyl)-3-(5-tert-butyl-2-methoxyphenyl)urea chemical structure, C27H31N3O5, CAS 284461-37-6
1-(4-(3-(Methylcarbamoyl)-4-methoxyphenoxy)phenyl)-3-(5-tert-butyl-2-methoxyphenyl)urea
CAS 284461-37-6C27H31N3O5
N-[4-(4-Aminophenoxy)phenyl]-N'-(2,4-difluorophenyl)urea chemical structure, C19H15F2N3O2, CAS 228544-75-0
N-[4-(4-Aminophenoxy)phenyl]-N'-(2,4-difluorophenyl)urea
CAS 228544-75-0C19H15F2N3O2
1-(4-(3-(Methylcarbamoyl)phenoxy)phenyl)-3-(3-tert-butylphenyl)urea chemical structure, C25H27N3O3, CAS 284461-33-2
1-(4-(3-(Methylcarbamoyl)phenoxy)phenyl)-3-(3-tert-butylphenyl)urea
CAS 284461-33-2C25H27N3O3
3-[4-[[[4-Chloro-3-(trifluoromethyl)anilino]-oxomethyl]amino]phenoxy]-N-methylbenzamide chemical structure, C22H17ClF3N3O3, CAS 284461-72-9
3-[4-[[[4-Chloro-3-(trifluoromethyl)anilino]-oxomethyl]amino]phenoxy]-N-methylbenzamide
CAS 284461-72-9C22H17ClF3N3O3
3-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureido]-phenoxy}-N-methyl-benzamide chemical structure, C23H20F3N3O4, CAS 228418-48-2
3-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureido]-phenoxy}-N-methyl-benzamide
CAS 228418-48-2C23H20F3N3O4
Urea, N-[3-bromo-4-(4-fluorophenoxy)phenyl]-N'-(3-chlorophenyl)- chemical structure, C19H13BrClFN2O2, CAS 823782-67-8
Urea, N-[3-bromo-4-(4-fluorophenoxy)phenyl]-N'-(3-chlorophenyl)-
CAS 823782-67-8C19H13BrClFN2O2
N-(2,5-Dichlorophenyl)-N'-(4-phenoxyphenyl)urea chemical structure, C19H14Cl2N2O2, CAS 178607-17-5
N-(2,5-Dichlorophenyl)-N'-(4-phenoxyphenyl)urea
CAS 178607-17-5C19H14Cl2N2O2
1-(3-Chloro-4-methylphenyl)-3-[4-(4-chlorophenoxy)phenyl]urea chemical structure, C20H16Cl2N2O2, CAS 883550-57-0
1-(3-Chloro-4-methylphenyl)-3-[4-(4-chlorophenoxy)phenyl]urea
CAS 883550-57-0C20H16Cl2N2O2
Sodium 5-(4-chlorophenoxy)-2-[[3-(trifluoromethyl)phenyl]carbamoylamino]benzenesulfonic acid chemical structure, C20H14ClF3N2NaO5S+, CAS 447-96-1
Sodium 5-(4-chlorophenoxy)-2-[[3-(trifluoromethyl)phenyl]carbamoylamino]benzenesulfonic acid
CAS 447-96-1C20H14ClF3N2NaO5S+
Sodium 4-chloro-5-(4-chlorophenoxy)-2-[[2-chloro-5-(trifluoromethyl)phenyl]carbamoylamino]benzenesulfonic acid chemical structure, C20H12Cl3F3N2NaO5S+, CAS 444-61-1
Sodium 4-chloro-5-(4-chlorophenoxy)-2-[[2-chloro-5-(trifluoromethyl)phenyl]carbamoylamino]benzenesulfonic acid
CAS 444-61-1C20H12Cl3F3N2NaO5S+
N-(3-Chloro-4-methylphenyl)-N'-(4-phenoxyphenyl)urea chemical structure, C20H17ClN2O2, CAS 853319-11-6
N-(3-Chloro-4-methylphenyl)-N'-(4-phenoxyphenyl)urea
CAS 853319-11-6C20H17ClN2O2
1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea chemical structure, C21H13ClF3N3O2, CAS 1313019-65-6
1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS 1313019-65-6C21H13ClF3N3O2