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Murcko scaffold

Ring system with 3 rings and 25 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
16
With full pages
5
Scaffold SMILES

O=C(Cc1ccccc1)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

2-(4-Methoxyphenyl)-N-[4-(1-piperidinylsulfonyl)phenyl]acetamide chemical structure, C20H24N2O4S, CAS 315672-13-0
2-(4-Methoxyphenyl)-N-[4-(1-piperidinylsulfonyl)phenyl]acetamide
CAS 315672-13-0C20H24N2O4S
2-(4-Methoxyphenyl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C21H26N2O4S, CAS 315671-26-2
2-(4-Methoxyphenyl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 315671-26-2C21H26N2O4S
N-[4-(4-Methylpiperidin-1-yl)sulfonylphenyl]-2-phenylacetamide chemical structure, C20H24N2O3S, CAS 431910-85-9
N-[4-(4-Methylpiperidin-1-yl)sulfonylphenyl]-2-phenylacetamide
CAS 431910-85-9C20H24N2O3S
2-(4-Fluorophenyl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C20H23FN2O3S, CAS 510763-78-7
2-(4-Fluorophenyl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 510763-78-7C20H23FN2O3S
2-(4-Chlorophenyl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C20H23ClN2O3S, CAS 524032-69-7
2-(4-Chlorophenyl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 524032-69-7C20H23ClN2O3S
2-(4-Bromophenyl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C20H23BrN2O3S, CAS 524677-50-7
2-(4-Bromophenyl)-N-{4-[(4-methylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 524677-50-7C20H23BrN2O3S
2-(2-Chloro-6-fluorophenyl)-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]acetamide chemical structure, C20H22ClFN2O3S, CAS 710989-28-9
2-(2-Chloro-6-fluorophenyl)-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]acetamide
CAS 710989-28-9C20H22ClFN2O3S
2-(4-Methylphenyl)-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]acetamide chemical structure, C21H26N2O3S, CAS 587844-20-0
2-(4-Methylphenyl)-N-[4-(4-methylpiperidin-1-yl)sulfonylphenyl]acetamide
CAS 587844-20-0C21H26N2O3S
2-(2-Nitrophenyl)-N-(4-piperidin-1-ylsulfonylphenyl)acetamide chemical structure, C19H21N3O5S, CAS 600146-73-4
2-(2-Nitrophenyl)-N-(4-piperidin-1-ylsulfonylphenyl)acetamide
CAS 600146-73-4C19H21N3O5S
2-(3,4-Dimethoxyphenyl)-N-(4-piperidin-1-ylsulfonylphenyl)acetamide chemical structure, C21H26N2O5S, CAS 600146-49-4
2-(3,4-Dimethoxyphenyl)-N-(4-piperidin-1-ylsulfonylphenyl)acetamide
CAS 600146-49-4C21H26N2O5S
2-(3-Methoxyphenyl)-N-(4-piperidin-1-ylsulfonylphenyl)acetamide chemical structure, C20H24N2O4S, CAS 851280-76-7
2-(3-Methoxyphenyl)-N-(4-piperidin-1-ylsulfonylphenyl)acetamide
CAS 851280-76-7C20H24N2O4S
2-Methoxy-2-phenyl-N-(4-piperidin-1-ylsulfonylphenyl)acetamide chemical structure, C20H24N2O4S, CAS 335393-11-8
2-Methoxy-2-phenyl-N-(4-piperidin-1-ylsulfonylphenyl)acetamide
CAS 335393-11-8C20H24N2O4S
N-[4-(4-Methylpiperidin-1-yl)sulfonylphenyl]-2-phenylbutanamide chemical structure, C22H28N2O3S, CAS 590377-54-1
N-[4-(4-Methylpiperidin-1-yl)sulfonylphenyl]-2-phenylbutanamide
CAS 590377-54-1C22H28N2O3S
2-Phenyl-N-(4-piperidin-1-ylsulfonylphenyl)butanamide chemical structure, C21H26N2O3S, CAS 600148-29-6
2-Phenyl-N-(4-piperidin-1-ylsulfonylphenyl)butanamide
CAS 600148-29-6C21H26N2O3S
2-(3,4-Dimethoxyphenyl)-N-{4-[(2-ethylpiperidin-1-yl)sulfonyl]phenyl}acetamide chemical structure, C23H30N2O5S, CAS 879079-93-3
2-(3,4-Dimethoxyphenyl)-N-{4-[(2-ethylpiperidin-1-yl)sulfonyl]phenyl}acetamide
CAS 879079-93-3C23H30N2O5S
2-(2-Fluorophenyl)-N-(4-piperidin-1-ylsulfonylphenyl)acetamide chemical structure, C19H21FN2O3S, CAS 872437-07-5
2-(2-Fluorophenyl)-N-(4-piperidin-1-ylsulfonylphenyl)acetamide
CAS 872437-07-5C19H21FN2O3S