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Murcko scaffold

4-(Benzenesulfonyl)-N-benzylpiperazine-1-carbothioamide scaffold

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
9
With full pages
5
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCN(C(=S)NCc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Benzenesulfonyl)-N-benzylpiperazine-1-carbothioamide page
Murcko scaffold O=S(=O)(c1ccccc1)N1CCN(C(=S)NCc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

N-Benzyl-4-(4-nitrophenyl)sulfonylpiperazine-1-carbothioamide chemical structure, C18H20N4O4S2, CAS 774546-21-3
N-Benzyl-4-(4-nitrophenyl)sulfonylpiperazine-1-carbothioamide
CAS 774546-21-3C18H20N4O4S2
N-[(4-Chlorophenyl)methyl]-4-(4-chlorophenyl)sulfonylpiperazine-1-carbothioamide chemical structure, C18H19Cl2N3O2S2, CAS 701973-07-1
N-[(4-Chlorophenyl)methyl]-4-(4-chlorophenyl)sulfonylpiperazine-1-carbothioamide
CAS 701973-07-1C18H19Cl2N3O2S2
N-Benzyl-4-(4-fluorobenzenesulfonyl)piperazine-1-carbothioamide chemical structure, C18H20FN3O2S2, CAS 794579-13-8
N-Benzyl-4-(4-fluorobenzenesulfonyl)piperazine-1-carbothioamide
CAS 794579-13-8C18H20FN3O2S2
N-Benzyl-4-(3-fluorobenzenesulfonyl)piperazine-1-carbothioamide chemical structure, C18H20FN3O2S2, CAS 794583-01-0
N-Benzyl-4-(3-fluorobenzenesulfonyl)piperazine-1-carbothioamide
CAS 794583-01-0C18H20FN3O2S2
4-(Benzenesulfonyl)-N-benzylpiperazine-1-carbothioamide chemical structure, C18H21N3O2S2, CAS 794585-07-2
4-(Benzenesulfonyl)-N-benzylpiperazine-1-carbothioamide
CAS 794585-07-2C18H21N3O2S2
N-Benzyl-4-(2-fluorobenzenesulfonyl)piperazine-1-carbothioamide chemical structure, C18H20FN3O2S2, CAS 796051-91-7
N-Benzyl-4-(2-fluorobenzenesulfonyl)piperazine-1-carbothioamide
CAS 796051-91-7C18H20FN3O2S2
N-Benzyl-4-(4-ethoxybenzenesulfonyl)piperazine-1-carbothioamide chemical structure, C20H25N3O3S2, CAS 796081-61-3
N-Benzyl-4-(4-ethoxybenzenesulfonyl)piperazine-1-carbothioamide
CAS 796081-61-3C20H25N3O3S2
N-Benzyl-4-(4-bromo-2,6-dichlorobenzenesulfonyl)piperazine-1-carbothioamide chemical structure, C18H18BrCl2N3O2S2, CAS 792961-35-4
N-Benzyl-4-(4-bromo-2,6-dichlorobenzenesulfonyl)piperazine-1-carbothioamide
CAS 792961-35-4C18H18BrCl2N3O2S2
4-(2,5-Dichlorophenyl)sulfonyl-N-[(4-fluorophenyl)methyl]piperazine-1-carbothioamide chemical structure, C18H18Cl2FN3O2S2, CAS 774546-30-4
4-(2,5-Dichlorophenyl)sulfonyl-N-[(4-fluorophenyl)methyl]piperazine-1-carbothioamide
CAS 774546-30-4C18H18Cl2FN3O2S2