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Murcko scaffold

Ring system with 3 rings and 19 atoms

61 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
61
With full pages
10
Scaffold SMILES

O=C1OC(=Cc2ccccc2)C=C1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1OC(=Cc2ccccc2)C=C1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 61 chemicals

Agn-PC-0JU41T chemical structure, C21H18O6, CAS 22736-30-7
Agn-PC-0JU41T
CAS 22736-30-7C21H18O6
(5Z)-5-Benzylidene-3-phenylfuran-2-one chemical structure, C17H12O2, CAS 38558-86-0
(5Z)-5-Benzylidene-3-phenylfuran-2-one
CAS 38558-86-0C17H12O2
(5Z)-5-Benzylidene-4-chloro-3-phenylfuran-2-one chemical structure, C17H11ClO2, CAS 20809-64-7
(5Z)-5-Benzylidene-4-chloro-3-phenylfuran-2-one
CAS 20809-64-7C17H11ClO2
delta2(5H),alpha-Furanacetic acid, 3-methoxy-5-oxo-alpha,4-diphenyl-, methyl ester chemical structure, C20H16O5, CAS 22628-22-4
delta2(5H),alpha-Furanacetic acid, 3-methoxy-5-oxo-alpha,4-diphenyl-, methyl ester
CAS 22628-22-4C20H16O5
(5E)-5-Benzylidene-3-phenylfuran-2-one chemical structure, C17H12O2
(5E)-5-Benzylidene-3-phenylfuran-2-one
C17H12O2
Aspulvinone E chemical structure, C17H12O5, CAS 49637-60-7
Aspulvinone E
CAS 49637-60-7C17H12O5
(5Z)-4-Hydroxy-3-(4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl)-5-((4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl)methylene)-2(5H)-furanone chemical structure, C27H28O5, CAS 57744-69-1
(5Z)-4-Hydroxy-3-(4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl)-5-((4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl)methylene)-2(5H)-furanone
CAS 57744-69-1C27H28O5
Benzeneacetic acid, 3-chloro-alpha-(4-(3-chlorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester, (E)- chemical structure, C19H12Cl2O5, CAS 32883-73-1
Benzeneacetic acid, 3-chloro-alpha-(4-(3-chlorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester, (E)-
CAS 32883-73-1C19H12Cl2O5
Benzeneacetic acid, 4-chloro-alpha-(4-(4-chlorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester, (E)- chemical structure, C19H12Cl2O5, CAS 37542-25-9
Benzeneacetic acid, 4-chloro-alpha-(4-(4-chlorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester, (E)-
CAS 37542-25-9C19H12Cl2O5
Benzeneacetic acid, 3-chloro-alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-, methyl ester chemical structure, C19H13ClO5, CAS 32883-83-3
Benzeneacetic acid, 3-chloro-alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-, methyl ester
CAS 32883-83-3C19H13ClO5
Benzeneacetic acid, 4-chloro-alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-, methyl ester chemical structure, C19H13ClO5, CAS 37542-23-7
Benzeneacetic acid, 4-chloro-alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-, methyl ester
CAS 37542-23-7C19H13ClO5
Benzeneacetic acid, alpha-(4-(3-chlorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester chemical structure, C19H13ClO5, CAS 33050-81-6
Benzeneacetic acid, alpha-(4-(3-chlorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester
CAS 33050-81-6C19H13ClO5
Benzeneacetic acid, alpha-(4-(4-chlorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester, (E)- chemical structure, C19H13ClO5, CAS 37542-22-6
Benzeneacetic acid, alpha-(4-(4-chlorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester, (E)-
CAS 37542-22-6C19H13ClO5
Benzeneacetic acid, 3,5-dichloro-alpha-(4-(3,5-dichlorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester chemical structure, C19H10Cl4O5, CAS 54805-72-0
Benzeneacetic acid, 3,5-dichloro-alpha-(4-(3,5-dichlorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester
CAS 54805-72-0C19H10Cl4O5
Benzeneacetic acid, 3,5-dichloro-alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-, methyl ester chemical structure, C19H12Cl2O5, CAS 39133-77-2
Benzeneacetic acid, 3,5-dichloro-alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-, methyl ester
CAS 39133-77-2C19H12Cl2O5
Benzeneacetic acid, alpha-(4-(3,5-dichlorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester chemical structure, C19H12Cl2O5, CAS 39133-76-1
Benzeneacetic acid, alpha-(4-(3,5-dichlorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester
CAS 39133-76-1C19H12Cl2O5
Benzeneacetic acid, alpha-(4-(3,4-dimethoxyphenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-3,4-dimethoxy-, methyl ester, (E)- chemical structure, C23H22O9, CAS 38746-89-3
Benzeneacetic acid, alpha-(4-(3,4-dimethoxyphenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-3,4-dimethoxy-, methyl ester, (E)-
CAS 38746-89-3C23H22O9
Benzeneacetic acid, 2-fluoro-alpha-(4-(2-fluorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester chemical structure, C19H12F2O5, CAS 54805-71-9
Benzeneacetic acid, 2-fluoro-alpha-(4-(2-fluorophenyl)-3-hydroxy-5-oxo-2(5H)-furanylidene)-, methyl ester
CAS 54805-71-9C19H12F2O5
Benzeneacetic acid, 4-hydroxy-alpha-(3-hydroxy-4-(4-hydroxyphenyl)-5-oxo-2(5H)-furanylidene)-, methyl ester chemical structure, C19H14O7, CAS 54805-70-8
Benzeneacetic acid, 4-hydroxy-alpha-(3-hydroxy-4-(4-hydroxyphenyl)-5-oxo-2(5H)-furanylidene)-, methyl ester
CAS 54805-70-8C19H14O7
Benzeneacetic acid, alpha-(3-hydroxy-4-(4-hydroxyphenyl)-5-oxo-2(5H)-furanylidene)-, methyl ester chemical structure, C19H14O6, CAS 54805-74-2
Benzeneacetic acid, alpha-(3-hydroxy-4-(4-hydroxyphenyl)-5-oxo-2(5H)-furanylidene)-, methyl ester
CAS 54805-74-2C19H14O6
Benzeneacetic acid, alpha-(3-hydroxy-4-(3-iodophenyl)-5-oxo-2(5H)-furanylidene)-3-iodo-, methyl ester chemical structure, C19H12I2O5, CAS 32883-76-4
Benzeneacetic acid, alpha-(3-hydroxy-4-(3-iodophenyl)-5-oxo-2(5H)-furanylidene)-3-iodo-, methyl ester
CAS 32883-76-4C19H12I2O5
Benzeneacetic acid, alpha-(3-hydroxy-4-(2-methylphenyl)-5-oxo-2(5H)-furanylidene)-2-methyl-, methyl ester chemical structure, C21H18O5, CAS 54805-67-3
Benzeneacetic acid, alpha-(3-hydroxy-4-(2-methylphenyl)-5-oxo-2(5H)-furanylidene)-2-methyl-, methyl ester
CAS 54805-67-3C21H18O5
Benzeneacetic acid, alpha-(3-hydroxy-4-(3-methylphenyl)-5-oxo-2(5H)-furanylidene)-3-methyl-, methyl ester chemical structure, C21H18O5, CAS 54805-66-2
Benzeneacetic acid, alpha-(3-hydroxy-4-(3-methylphenyl)-5-oxo-2(5H)-furanylidene)-3-methyl-, methyl ester
CAS 54805-66-2C21H18O5
Benzeneacetic acid, alpha-(3-hydroxy-4-(4-methylphenyl)-5-oxo-2(5H)-furanylidene)-4-methyl-, methyl ester, (E)- chemical structure, C21H18O5, CAS 37542-24-8
Benzeneacetic acid, alpha-(3-hydroxy-4-(4-methylphenyl)-5-oxo-2(5H)-furanylidene)-4-methyl-, methyl ester, (E)-
CAS 37542-24-8C21H18O5