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Murcko scaffold

Ring system with 3 rings and 21 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
18
With full pages
8
Scaffold SMILES

O=S(=O)(N1CCCCC1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(N1CCCCC1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

1-(2,4-Dimethylphenyl)-4-piperidin-1-ylsulfonylpiperazine chemical structure, C17H27N3O2S, CAS 692762-00-8
1-(2,4-Dimethylphenyl)-4-piperidin-1-ylsulfonylpiperazine
CAS 692762-00-8C17H27N3O2S
4-(3,4-Dimethylphenyl)-1-(piperidylsulfonyl)piperazine chemical structure, C17H27N3O2S, CAS 701931-01-3
4-(3,4-Dimethylphenyl)-1-(piperidylsulfonyl)piperazine
CAS 701931-01-3C17H27N3O2S
1-(4-Fluorophenyl)-4-piperidin-1-ylsulfonylpiperazine chemical structure, C15H22FN3O2S, CAS 712345-13-6
1-(4-Fluorophenyl)-4-piperidin-1-ylsulfonylpiperazine
CAS 712345-13-6C15H22FN3O2S
4-(3-Chloro-4-methylphenyl)-1-(piperidylsulfonyl)piperazine chemical structure, C16H24ClN3O2S, CAS 692761-99-2
4-(3-Chloro-4-methylphenyl)-1-(piperidylsulfonyl)piperazine
CAS 692761-99-2C16H24ClN3O2S
1-(5-Chloro-2-methylphenyl)-4-(1-piperidinylsulfonyl)piperazine chemical structure, C16H24ClN3O2S, CAS 701947-79-7
1-(5-Chloro-2-methylphenyl)-4-(1-piperidinylsulfonyl)piperazine
CAS 701947-79-7C16H24ClN3O2S
1-(2,5-Dichlorophenyl)-4-piperidin-1-ylsulfonylpiperazine chemical structure, C15H21Cl2N3O2S, CAS 708236-87-7
1-(2,5-Dichlorophenyl)-4-piperidin-1-ylsulfonylpiperazine
CAS 708236-87-7C15H21Cl2N3O2S
1-(2-Fluoro-phenyl)-4-(piperidine-1-sulfonyl)-piperazine chemical structure, C15H22FN3O2S, CAS 801225-13-8
1-(2-Fluoro-phenyl)-4-(piperidine-1-sulfonyl)-piperazine
CAS 801225-13-8C15H22FN3O2S
1-(2,6-Dimethylphenyl)-4-(1-piperidinylsulfonyl)piperazine chemical structure, C17H27N3O2S, CAS 825608-11-5
1-(2,6-Dimethylphenyl)-4-(1-piperidinylsulfonyl)piperazine
CAS 825608-11-5C17H27N3O2S
1-Mesityl-4-(1-piperidinylsulfonyl)piperazine chemical structure, C18H29N3O2S, CAS 825608-14-8
1-Mesityl-4-(1-piperidinylsulfonyl)piperazine
CAS 825608-14-8C18H29N3O2S
1-(Piperidin-1-ylsulfonyl)-4-(o-tolyl)piperazine chemical structure, C16H25N3O2S, CAS 825608-15-9
1-(Piperidin-1-ylsulfonyl)-4-(o-tolyl)piperazine
CAS 825608-15-9C16H25N3O2S
1-(2-Fluorophenyl)-4-((4-methylpiperidin-1-yl)sulfonyl)piperazine chemical structure, C16H24FN3O2S, CAS 879053-71-1
1-(2-Fluorophenyl)-4-((4-methylpiperidin-1-yl)sulfonyl)piperazine
CAS 879053-71-1C16H24FN3O2S
1-(4-Fluorophenyl)-4-((4-methylpiperidin-1-yl)sulfonyl)piperazine chemical structure, C16H24FN3O2S, CAS 879053-78-8
1-(4-Fluorophenyl)-4-((4-methylpiperidin-1-yl)sulfonyl)piperazine
CAS 879053-78-8C16H24FN3O2S
1-(2-Chlorophenyl)-4-(4-methylpiperidin-1-yl)sulfonylpiperazine chemical structure, C16H24ClN3O2S, CAS 879054-60-1
1-(2-Chlorophenyl)-4-(4-methylpiperidin-1-yl)sulfonylpiperazine
CAS 879054-60-1C16H24ClN3O2S
1-(5-Chloro-2-methylphenyl)-4-((4-methylpiperidin-1-yl)sulfonyl)piperazine chemical structure, C17H26ClN3O2S, CAS 890604-84-9
1-(5-Chloro-2-methylphenyl)-4-((4-methylpiperidin-1-yl)sulfonyl)piperazine
CAS 890604-84-9C17H26ClN3O2S
1-(4-Methoxyphenyl)-4-((4-methylpiperidin-1-yl)sulfonyl)piperazine chemical structure, C17H27N3O3S, CAS 927640-64-0
1-(4-Methoxyphenyl)-4-((4-methylpiperidin-1-yl)sulfonyl)piperazine
CAS 927640-64-0C17H27N3O3S
4-(3-Chloro-2-methylphenyl)-1-[(4-methylpiperidyl)sulfonyl]piperazine chemical structure, C17H26ClN3O2S, CAS 890598-88-6
4-(3-Chloro-2-methylphenyl)-1-[(4-methylpiperidyl)sulfonyl]piperazine
CAS 890598-88-6C17H26ClN3O2S
1-(4-Methoxyphenyl)-4-(piperidin-1-ylsulfonyl)piperazine chemical structure, C16H25N3O3S, CAS 942033-68-3
1-(4-Methoxyphenyl)-4-(piperidin-1-ylsulfonyl)piperazine
CAS 942033-68-3C16H25N3O3S
4-(4-Chlorophenyl)-1-[(4-methylpiperidyl)sulfonyl]piperazine chemical structure, C16H24ClN3O2S, CAS 890601-40-8
4-(4-Chlorophenyl)-1-[(4-methylpiperidyl)sulfonyl]piperazine
CAS 890601-40-8C16H24ClN3O2S