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Murcko scaffold

Morpholin-4-yl-(4-phenyl-piperazin-1-yl)-methanone scaffold

22 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
22
With full pages
13
Scaffold SMILES

O=C(N1CCOCC1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Morpholin-4-yl-(4-phenyl-piperazin-1-yl)-methanone page
Murcko scaffold O=C(N1CCOCC1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

[4-(3,5-Dimethyl-phenyl)-piperazin-1-yl]-morpholin-4-yl-methanone chemical structure, C17H25N3O2, CAS 799257-98-0
[4-(3,5-Dimethyl-phenyl)-piperazin-1-yl]-morpholin-4-yl-methanone
CAS 799257-98-0C17H25N3O2
(4-(2,5-Dichlorophenyl)piperazin-1-yl)(morpholino)methanone chemical structure, C15H19Cl2N3O2, CAS 501104-51-4
(4-(2,5-Dichlorophenyl)piperazin-1-yl)(morpholino)methanone
CAS 501104-51-4C15H19Cl2N3O2
4-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]morpholine chemical structure, C16H23N3O3, CAS 586996-95-4
4-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]morpholine
CAS 586996-95-4C16H23N3O3
[4-(2,3-Dimethylphenyl)piperazin-1-yl]-morpholin-4-yl-methanone chemical structure, C17H25N3O2, CAS 6622-51-1
[4-(2,3-Dimethylphenyl)piperazin-1-yl]-morpholin-4-yl-methanone
CAS 6622-51-1C17H25N3O2
[4-(2-Methoxyphenyl)piperazin-1-yl]-morpholin-4-ylmethanone chemical structure, C16H23N3O3, CAS 346713-69-7
[4-(2-Methoxyphenyl)piperazin-1-yl]-morpholin-4-ylmethanone
CAS 346713-69-7C16H23N3O3
4-(2-Fluorophenyl)piperazinyl morpholin-4-yl ketone chemical structure, C15H20FN3O2, CAS 505088-19-7
4-(2-Fluorophenyl)piperazinyl morpholin-4-yl ketone
CAS 505088-19-7C15H20FN3O2
[4-(4-Fluorophenyl)piperazin-1-yl]-morpholin-4-ylmethanone chemical structure, C15H20FN3O2, CAS 346713-94-8
[4-(4-Fluorophenyl)piperazin-1-yl]-morpholin-4-ylmethanone
CAS 346713-94-8C15H20FN3O2
Morpholin-4-yl-(4-phenyl-piperazin-1-yl)-methanone chemical structure, C15H21N3O2, CAS 349118-82-7
Morpholin-4-yl-(4-phenyl-piperazin-1-yl)-methanone
CAS 349118-82-7C15H21N3O2
(4-(2,4-Dimethylphenyl)piperazin-1-yl)(morpholino)methanone chemical structure, C17H25N3O2, CAS 501104-52-5
(4-(2,4-Dimethylphenyl)piperazin-1-yl)(morpholino)methanone
CAS 501104-52-5C17H25N3O2
4-(3-Chloro-4-methylphenyl)piperazinyl morpholin-4-yl ketone chemical structure, C16H22ClN3O2, CAS 501104-27-4
4-(3-Chloro-4-methylphenyl)piperazinyl morpholin-4-yl ketone
CAS 501104-27-4C16H22ClN3O2
4-(2,6-Dimethylphenyl)piperazinyl morpholin-4-yl ketone chemical structure, C17H25N3O2, CAS 713096-33-4
4-(2,6-Dimethylphenyl)piperazinyl morpholin-4-yl ketone
CAS 713096-33-4C17H25N3O2
(4-(3-Chlorophenyl)piperazin-1-yl)(morpholino)methanone chemical structure, C15H20ClN3O2, CAS 346713-93-7
(4-(3-Chlorophenyl)piperazin-1-yl)(morpholino)methanone
CAS 346713-93-7C15H20ClN3O2
[4-(2,3-Dichlorophenyl)piperazin-1-yl](morpholin-4-yl)methanone chemical structure, C15H19Cl2N3O2, CAS 695174-68-6
[4-(2,3-Dichlorophenyl)piperazin-1-yl](morpholin-4-yl)methanone
CAS 695174-68-6C15H19Cl2N3O2
[4-(4-Chlorophenyl)piperazin-1-yl](morpholin-4-yl)methanone chemical structure, C15H20ClN3O2, CAS 700856-05-9
[4-(4-Chlorophenyl)piperazin-1-yl](morpholin-4-yl)methanone
CAS 700856-05-9C15H20ClN3O2
4-(4-Ethylphenyl)piperazinyl morpholin-4-yl ketone chemical structure, C17H25N3O2, CAS 700861-92-3
4-(4-Ethylphenyl)piperazinyl morpholin-4-yl ketone
CAS 700861-92-3C17H25N3O2
(4-(3,4-Dichlorophenyl)piperazin-1-yl)(morpholino)methanone chemical structure, C15H19Cl2N3O2, CAS 501104-39-8
(4-(3,4-Dichlorophenyl)piperazin-1-yl)(morpholino)methanone
CAS 501104-39-8C15H19Cl2N3O2
4-(3,4-Dimethylphenyl)piperazinyl morpholin-4-yl ketone chemical structure, C17H25N3O2, CAS 501104-33-2
4-(3,4-Dimethylphenyl)piperazinyl morpholin-4-yl ketone
CAS 501104-33-2C17H25N3O2
Morpholin-4-yl[4-(4-nitrophenyl)piperazin-1-yl]methanone chemical structure, C15H20N4O4, CAS 332943-12-1
Morpholin-4-yl[4-(4-nitrophenyl)piperazin-1-yl]methanone
CAS 332943-12-1C15H20N4O4
4-[4-(5-Chloro-2-methylphenyl)piperazine-1-carbonyl]morpholine chemical structure, C16H22ClN3O2, CAS 497060-50-1
4-[4-(5-Chloro-2-methylphenyl)piperazine-1-carbonyl]morpholine
CAS 497060-50-1C16H22ClN3O2
[4-(3-Methoxyphenyl)piperazin-1-yl]-morpholin-4-ylmethanone chemical structure, C16H23N3O3, CAS 862199-05-1
[4-(3-Methoxyphenyl)piperazin-1-yl]-morpholin-4-ylmethanone
CAS 862199-05-1C16H23N3O3
[4-(4-Aminophenyl)piperazin-1-yl]-morpholin-4-ylmethanone chemical structure, C15H22N4O2, CAS 1353553-19-1
[4-(4-Aminophenyl)piperazin-1-yl]-morpholin-4-ylmethanone
CAS 1353553-19-1C15H22N4O2
[4-(2,4-Dichlorophenyl)piperazin-1-yl]-morpholin-4-ylmethanone chemical structure, C15H19Cl2N3O2, CAS 1548116-54-6
[4-(2,4-Dichlorophenyl)piperazin-1-yl]-morpholin-4-ylmethanone
CAS 1548116-54-6C15H19Cl2N3O2