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Murcko scaffold

Pyrimidine scaffold

19,000 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
19,000
With full pages
2,066
Scaffold SMILES

c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Pyrimidine page
Murcko scaffold c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,441 to 1,488 of 19,000 chemicals

4-Methyl-N-(prop-2-yn-1-yl)pyrimidin-2-amine chemical structure, C8H9N3, CAS 1022232-53-6
4-Methyl-N-(prop-2-yn-1-yl)pyrimidin-2-amine
CAS 1022232-53-6C8H9N3
4-Chloro-6-methyl-2-(propan-2-yl)pyrimidine chemical structure, C8H11ClN2, CAS 4595-69-1
4-Chloro-6-methyl-2-(propan-2-yl)pyrimidine
CAS 4595-69-1C8H11ClN2
Methyl 4-methyl-2-(methylthio)pyrimidine-5-carboxylate chemical structure, C8H10N2O2S, CAS 166392-24-1
Methyl 4-methyl-2-(methylthio)pyrimidine-5-carboxylate
CAS 166392-24-1C8H10N2O2S
2-[[6-Amino-2-(3-methylbutylamino)-5-nitropyrimidin-4-yl]amino]ethanol chemical structure, C11H20N6O3, CAS 573694-04-9
2-[[6-Amino-2-(3-methylbutylamino)-5-nitropyrimidin-4-yl]amino]ethanol
CAS 573694-04-9C11H20N6O3
2-Methyl-4-(pyrimidin-5-yl)but-3-yn-2-ol chemical structure, C9H10N2O, CAS 153286-92-1
2-Methyl-4-(pyrimidin-5-yl)but-3-yn-2-ol
CAS 153286-92-1C9H10N2O
2-Methyl-N-{2,2,2-trichloro-1-[(6-methylpyrimidin-4-yl)sulfanyl]ethyl}propanamide chemical structure, C11H14Cl3N3OS, CAS 635700-71-9
2-Methyl-N-{2,2,2-trichloro-1-[(6-methylpyrimidin-4-yl)sulfanyl]ethyl}propanamide
CAS 635700-71-9C11H14Cl3N3OS
6-Methylsulfanylpyrimidine-4-carboxylic acid chemical structure, C6H6N2O2S, CAS 301342-78-9
6-Methylsulfanylpyrimidine-4-carboxylic acid
CAS 301342-78-9C6H6N2O2S
Ethyl 2-(4,6-dimethylpyrimidin-2-yl)oxyacetate chemical structure, C10H14N2O3, CAS 77165-99-2
Ethyl 2-(4,6-dimethylpyrimidin-2-yl)oxyacetate
CAS 77165-99-2C10H14N2O3
4-Chloro-2,6-dimethoxy-5-nitropyrimidine chemical structure, C6H6ClN3O4, CAS 60331-03-5
4-Chloro-2,6-dimethoxy-5-nitropyrimidine
CAS 60331-03-5C6H6ClN3O4
N'-(5-Cyanopyrimidin-2-yl)-N-methoxymethanimidamide chemical structure, C7H7N5O
N'-(5-Cyanopyrimidin-2-yl)-N-methoxymethanimidamide
C7H7N5O
3-Penten-2-one, 3-[(4,6-dimethyl-2-pyrimidinyl)thio]-4-hydroxy- chemical structure, C11H14N2O2S, CAS 90331-21-8
3-Penten-2-one, 3-[(4,6-dimethyl-2-pyrimidinyl)thio]-4-hydroxy-
CAS 90331-21-8C11H14N2O2S
2-[[6-Amino-2-(butan-2-ylamino)-5-nitropyrimidin-4-yl]amino]ethanol chemical structure, C10H18N6O3, CAS 672330-34-6
2-[[6-Amino-2-(butan-2-ylamino)-5-nitropyrimidin-4-yl]amino]ethanol
CAS 672330-34-6C10H18N6O3
4-Chloro-6-(dimethylamino)pyrimidine-5-carbaldehyde chemical structure, C7H8ClN3O, CAS 14160-95-3
4-Chloro-6-(dimethylamino)pyrimidine-5-carbaldehyde
CAS 14160-95-3C7H8ClN3O
1-((6-Amino-5-nitropyrimidin-4-yl)amino)propan-2-ol chemical structure, C7H11N5O3, CAS 85446-52-2
1-((6-Amino-5-nitropyrimidin-4-yl)amino)propan-2-ol
CAS 85446-52-2C7H11N5O3
2,4,6-Tris(1,1-dimethylethyl)pyrimidine chemical structure, C16H28N2, CAS 67490-21-5
2,4,6-Tris(1,1-dimethylethyl)pyrimidine
CAS 67490-21-5C16H28N2
N-Hexyl-2-isopropyl-6-methyl-4-pyrimidinamine chemical structure, C14H25N3, CAS 604790-51-4
N-Hexyl-2-isopropyl-6-methyl-4-pyrimidinamine
CAS 604790-51-4C14H25N3
5-Fluoropyrimidin-4-amine chemical structure, C4H4FN3, CAS 811450-26-7
5-Fluoropyrimidin-4-amine
CAS 811450-26-7C4H4FN3
5-Methoxy-N,N,2-trimethylpyrimidin-4-amine chemical structure, C8H13N3O, CAS 634154-64-6
5-Methoxy-N,N,2-trimethylpyrimidin-4-amine
CAS 634154-64-6C8H13N3O
2-Acetamido-4,6-dimethylpyrimidine chemical structure, C8H11N3O, CAS 15755-12-1
2-Acetamido-4,6-dimethylpyrimidine
CAS 15755-12-1C8H11N3O
2-Chloro-6-methoxypyrimidine-4-carboxylic acid chemical structure, C6H5ClN2O3, CAS 447432-93-1
2-Chloro-6-methoxypyrimidine-4-carboxylic acid
CAS 447432-93-1C6H5ClN2O3
2-(Dimethylamino)-4-(ethylamino)-5-(nitro)pyrimidine chemical structure, C8H13N5O2, CAS 98427-90-8
2-(Dimethylamino)-4-(ethylamino)-5-(nitro)pyrimidine
CAS 98427-90-8C8H13N5O2
N~1~-(2-isopropyl-6-methyl-4-pyrimidinyl)-N~3~,N~3~-dimethyl-1,3-propanediamine chemical structure, C13H24N4, CAS 691873-29-7
N~1~-(2-isopropyl-6-methyl-4-pyrimidinyl)-N~3~,N~3~-dimethyl-1,3-propanediamine
CAS 691873-29-7C13H24N4
N-Allyl-6-(methoxymethyl)-2-methyl-4-pyrimidinamine chemical structure, C10H15N3O, CAS 478043-20-8
N-Allyl-6-(methoxymethyl)-2-methyl-4-pyrimidinamine
CAS 478043-20-8C10H15N3O
2-[[6-Amino-2-[3-(diethylamino)propylamino]-5-nitropyrimidin-4-yl]amino]ethanol chemical structure, C13H25N7O3, CAS 714228-04-3
2-[[6-Amino-2-[3-(diethylamino)propylamino]-5-nitropyrimidin-4-yl]amino]ethanol
CAS 714228-04-3C13H25N7O3