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Murcko scaffold

Pyrimidine scaffold

19,000 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
19,000
With full pages
2,066
Scaffold SMILES

c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Pyrimidine page
Murcko scaffold c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,489 to 1,536 of 19,000 chemicals

2-((2-Amino-5-chloro-6-methyl-4-pyrimidinyl)sulfanyl)acetic acid chemical structure, C7H8ClN3O2S, CAS 338976-58-2
2-((2-Amino-5-chloro-6-methyl-4-pyrimidinyl)sulfanyl)acetic acid
CAS 338976-58-2C7H8ClN3O2S
P-2-Pyrimidinylphosphonic acid chemical structure, C4H5N2O3P, CAS 101257-34-5
P-2-Pyrimidinylphosphonic acid
CAS 101257-34-5C4H5N2O3P
2-Chloro-N-(pyrimidin-2-yl)propanamide chemical structure, C7H8ClN3O, CAS 731011-86-2
2-Chloro-N-(pyrimidin-2-yl)propanamide
CAS 731011-86-2C7H8ClN3O
Sodium Pyrimidine-2-sulfonate chemical structure, C4H3N2NaO3S, CAS 40828-57-7
Sodium Pyrimidine-2-sulfonate
CAS 40828-57-7C4H3N2NaO3S
N-Allyl-2-(methylsulfanyl)-6-(trifluoromethyl)-4-pyrimidinamine chemical structure, C9H10F3N3S, CAS 339019-59-9
N-Allyl-2-(methylsulfanyl)-6-(trifluoromethyl)-4-pyrimidinamine
CAS 339019-59-9C9H10F3N3S
2-Amino-4-(trifluoromethyl)pyrimidine-5-carboxylic acid chemical structure, C6H4F3N3O2, CAS 149771-23-3
2-Amino-4-(trifluoromethyl)pyrimidine-5-carboxylic acid
CAS 149771-23-3C6H4F3N3O2
N'-(6-Amino-5-nitropyrimidin-4-yl)formohydrazide chemical structure, C5H6N6O3, CAS 6274-43-7
N'-(6-Amino-5-nitropyrimidin-4-yl)formohydrazide
CAS 6274-43-7C5H6N6O3
4-Azido-6-methylpyrimidin-2-amine chemical structure, C5H6N6, CAS 459437-59-3
4-Azido-6-methylpyrimidin-2-amine
CAS 459437-59-3C5H6N6
5-Hydroxypyrimidine-4-carboxylic acid chemical structure, C5H4N2O3, CAS 201991-89-1
5-Hydroxypyrimidine-4-carboxylic acid
CAS 201991-89-1C5H4N2O3
4-Methyl-6-(2,2,3,3-tetrafluoropropoxy)pyrimidin-2-amine chemical structure, C8H9F4N3O, CAS 294197-08-3
4-Methyl-6-(2,2,3,3-tetrafluoropropoxy)pyrimidin-2-amine
CAS 294197-08-3C8H9F4N3O
2-((1-Methyl-2-oxopropyl)sulfanyl)-5-pyrimidinecarbonitrile chemical structure, C9H9N3OS, CAS 338420-98-7
2-((1-Methyl-2-oxopropyl)sulfanyl)-5-pyrimidinecarbonitrile
CAS 338420-98-7C9H9N3OS
N-Allyl-2-methyl-6-((methylsulfanyl)methyl)-4-pyrimidinamine chemical structure, C10H15N3S, CAS 478031-27-5
N-Allyl-2-methyl-6-((methylsulfanyl)methyl)-4-pyrimidinamine
CAS 478031-27-5C10H15N3S
6-Fluoro-4-N-methylpyrimidine-2,4-diamine chemical structure, C5H7FN4, CAS 165258-66-2
6-Fluoro-4-N-methylpyrimidine-2,4-diamine
CAS 165258-66-2C5H7FN4
2-[(2-Amino-6-fluoropyrimidin-4-yl)amino]ethanol chemical structure, C6H9FN4O, CAS 188987-84-0
2-[(2-Amino-6-fluoropyrimidin-4-yl)amino]ethanol
CAS 188987-84-0C6H9FN4O
4-(2-Methoxyethoxy)-6-methylpyrimidin-2-amine chemical structure, C8H13N3O2, CAS 75435-54-0
4-(2-Methoxyethoxy)-6-methylpyrimidin-2-amine
CAS 75435-54-0C8H13N3O2
4,5-Dichloro-6-methylpyrimidin-2-amine chemical structure, C5H5Cl2N3, CAS 7749-60-2
4,5-Dichloro-6-methylpyrimidin-2-amine
CAS 7749-60-2C5H5Cl2N3
5-Bromo-2-(ethylthio)pyrimidine-4-carboxylic Acid chemical structure, C7H7BrN2O2S, CAS 327168-15-0
5-Bromo-2-(ethylthio)pyrimidine-4-carboxylic Acid
CAS 327168-15-0C7H7BrN2O2S
2-Chloro-4-methoxy-5-nitropyrimidine chemical structure, C5H4ClN3O3, CAS 282102-07-2
2-Chloro-4-methoxy-5-nitropyrimidine
CAS 282102-07-2C5H4ClN3O3
4-Chloro-6-ethoxypyrimidin-2-amine chemical structure, C6H8ClN3O, CAS 89784-02-1
4-Chloro-6-ethoxypyrimidin-2-amine
CAS 89784-02-1C6H8ClN3O
2-Aminopyrimidine-5-carbonitrile chemical structure, C5H4N4, CAS 1753-48-6
2-Aminopyrimidine-5-carbonitrile
CAS 1753-48-6C5H4N4
2,4-Dichloro-6-methoxypyrimidine chemical structure, C5H4Cl2N2O, CAS 43212-41-5
2,4-Dichloro-6-methoxypyrimidine
CAS 43212-41-5C5H4Cl2N2O
Ethyl 4-[(2-methoxyethyl)amino]-2-(methylsulfanyl)-5-pyrimidinecarboxylate chemical structure, C11H17N3O3S, CAS 76360-91-3
Ethyl 4-[(2-methoxyethyl)amino]-2-(methylsulfanyl)-5-pyrimidinecarboxylate
CAS 76360-91-3C11H17N3O3S
2-[2-(Carboxymethylsulfanyl)-6-methylpyrimidin-4-yl]sulfanylacetic acid chemical structure, C9H10N2O4S2, CAS 131342-66-0
2-[2-(Carboxymethylsulfanyl)-6-methylpyrimidin-4-yl]sulfanylacetic acid
CAS 131342-66-0C9H10N2O4S2
N-(5-Iodo-2,6-dimethyl-4-pyrimidinyl)-N-(3-methoxypropyl)amine chemical structure, C10H16IN3O, CAS 477888-24-7
N-(5-Iodo-2,6-dimethyl-4-pyrimidinyl)-N-(3-methoxypropyl)amine
CAS 477888-24-7C10H16IN3O