Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 3 rings and 16 atoms

53 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 16
Chemicals: 53
With full pages: 3

Scaffold SMILES

O=c1c2sccc2ncn1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1c2sccc2ncn1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 53 chemicals

2-Methyl-3-(2-methylphenyl)thieno[3,2-d]pyrimidin-4-one chemical structure, C14H12N2OS, CAS 16234-12-1

2-Methyl-3-(2-methylphenyl)thieno[3,2-d]pyrimidin-4-one

CAS 16234-12-1C₁₄H₁₂N₂OS

2-[(Difluoromethyl)sulfanyl]-3-phenylthieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C13H8F2N2OS2, CAS 477859-73-7

2-[(Difluoromethyl)sulfanyl]-3-phenylthieno[3,2-d]pyrimidin-4(3H)-one

CAS 477859-73-7C₁₃H₈F₂N₂OS₂

3-(4-Chlorophenyl)-2-methylthieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C13H9ClN2OS, CAS 16234-13-2

3-(4-Chlorophenyl)-2-methylthieno[3,2-d]pyrimidin-4(3H)-one

CAS 16234-13-2C₁₃H₉ClN₂OS

3-Phenyl-2-[(3,4,4-trifluoro-3-butenyl)sulfanyl]thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C16H11F3N2OS2, CAS 477886-76-3

3-Phenyl-2-[(3,4,4-trifluoro-3-butenyl)sulfanyl]thieno[3,2-d]pyrimidin-4(3H)-one

CAS 477886-76-3C₁₆H₁₁F₃N₂OS₂

2-(Allylsulfanyl)-3-phenylthieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C15H12N2OS2, CAS 338779-19-4

2-(Allylsulfanyl)-3-phenylthieno[3,2-d]pyrimidin-4(3H)-one

CAS 338779-19-4C₁₅H₁₂N₂OS₂

3-Phenyl-2-(2-propynylsulfanyl)thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C15H10N2OS2, CAS 338779-21-8

3-Phenyl-2-(2-propynylsulfanyl)thieno[3,2-d]pyrimidin-4(3H)-one

CAS 338779-21-8C₁₅H₁₀N₂OS₂

N-Butyl-2-[3-(4-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl]sulfanyl-N-methylacetamide chemical structure, C20H23N3O3S2, CAS 6766-39-8

N-Butyl-2-[3-(4-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl]sulfanyl-N-methylacetamide

CAS 6766-39-8C₂₀H₂₃N₃O₃S₂

2-[3-(4-Methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl]sulfanyl-N-(3-methoxypropyl)acetamide chemical structure, C19H21N3O4S2, CAS 6766-40-1

2-[3-(4-Methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl]sulfanyl-N-(3-methoxypropyl)acetamide

CAS 6766-40-1C₁₉H₂₁N₃O₄S₂

2-(Methylsulfanyl)-3-phenylthieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C13H10N2OS2, CAS 338779-17-2

2-(Methylsulfanyl)-3-phenylthieno[3,2-d]pyrimidin-4(3H)-one

CAS 338779-17-2C₁₃H₁₀N₂OS₂

N,N-Diethyl-2-{[3-(2-fluorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C18H18FN3O2S2, CAS 1260987-47-0

N,N-Diethyl-2-{[3-(2-fluorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide

CAS 1260987-47-0C₁₈H₁₈FN₃O₂S₂

N-(Butan-2-yl)-2-{[3-(2-fluorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C18H18FN3O2S2, CAS 1261019-65-1

N-(Butan-2-yl)-2-{[3-(2-fluorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide

CAS 1261019-65-1C₁₈H₁₈FN₃O₂S₂

2-{[3-(2-Fluorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(3-methylbutyl)acetamide chemical structure, C19H20FN3O2S2, CAS 1261002-63-4

2-{[3-(2-Fluorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(3-methylbutyl)acetamide

CAS 1261002-63-4C₁₉H₂₀FN₃O₂S₂

2-{[3-(2-Fluorophenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(propan-2-yl)acetamide chemical structure, C17H16FN3O2S2, CAS 1261013-37-9

2-{[3-(2-Fluorophenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(propan-2-yl)acetamide

CAS 1261013-37-9C₁₇H₁₆FN₃O₂S₂

N-tert-Butyl-2-{[3-(2-fluorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C18H18FN3O2S2, CAS 1260987-62-9

N-tert-Butyl-2-{[3-(2-fluorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide

CAS 1260987-62-9C₁₈H₁₈FN₃O₂S₂

2-{[3-(4-Chlorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N,N-diethylacetamide chemical structure, C18H18ClN3O2S2, CAS 1260916-07-1

2-{[3-(4-Chlorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N,N-diethylacetamide

CAS 1260916-07-1C₁₈H₁₈ClN₃O₂S₂

N-Butyl-2-{[3-(4-chlorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-ethylacetamide chemical structure, C20H22ClN3O2S2, CAS 1260987-88-9

N-Butyl-2-{[3-(4-chlorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-ethylacetamide

CAS 1260987-88-9C₂₀H₂₂ClN₃O₂S₂

N-Butyl-2-{[3-(3,5-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C20H23N3O2S2, CAS 1260988-65-5

N-Butyl-2-{[3-(3,5-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide

CAS 1260988-65-5C₂₀H₂₃N₃O₂S₂

2-{[3-(3,5-Dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(2-methoxyethyl)acetamide chemical structure, C19H21N3O3S2, CAS 1260936-03-5

2-{[3-(3,5-Dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(2-methoxyethyl)acetamide

CAS 1260936-03-5C₁₉H₂₁N₃O₃S₂

N-(Butan-2-yl)-2-{[3-(3,5-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C20H23N3O2S2, CAS 1260940-25-7

N-(Butan-2-yl)-2-{[3-(3,5-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide

CAS 1260940-25-7C₂₀H₂₃N₃O₂S₂

2-{[3-(3,5-Dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(3-methylbutyl)acetamide chemical structure, C21H25N3O2S2, CAS 1260914-39-3

2-{[3-(3,5-Dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(3-methylbutyl)acetamide

CAS 1260914-39-3C₂₁H₂₅N₃O₂S₂

N-Butyl-2-{[3-(3,5-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-ethylacetamide chemical structure, C22H27N3O2S2, CAS 1260937-03-8

N-Butyl-2-{[3-(3,5-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-ethylacetamide

CAS 1260937-03-8C₂₂H₂₇N₃O₂S₂

2-{[3-(3,5-Dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(propan-2-yl)acetamide chemical structure, C19H21N3O2S2, CAS 1260990-35-9

2-{[3-(3,5-Dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(propan-2-yl)acetamide

CAS 1260990-35-9C₁₉H₂₁N₃O₂S₂

2-{[3-(3,5-Dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-propylacetamide chemical structure, C19H21N3O2S2, CAS 1261016-84-5

2-{[3-(3,5-Dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-propylacetamide

CAS 1261016-84-5C₁₉H₂₁N₃O₂S₂

N-(Butan-2-yl)-2-{[3-(2,4-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C20H23N3O2S2, CAS 1260909-88-3

N-(Butan-2-yl)-2-{[3-(2,4-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide

CAS 1260909-88-3C₂₀H₂₃N₃O₂S₂