CompoundList
Sign in
Murcko scaffold

1-(Biphenyl-4-ylmethyl)-1H-imidazole scaffold

30 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
30
With full pages
5
Scaffold SMILES

c1ccc(-c2ccc(Cn3ccnc3)cc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Biphenyl-4-ylmethyl)-1H-imidazole page
Murcko scaffold c1ccc(-c2ccc(Cn3ccnc3)cc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

4'-((2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)(1,1'-biphenyl)-2-carboxylic acid chemical structure, C22H23ClN2O3, CAS 114798-27-5
4'-((2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)(1,1'-biphenyl)-2-carboxylic acid
CAS 114798-27-5C22H23ClN2O3
4'-((2-Butyl-4-(hydroxymethyl)-5-chloro-1H-imidazolyl)methyl)-2',6'-dimethoxy(1,1'-biphenyl)-2-carboxylic acid chemical structure, C24H27ClN2O5, CAS 134360-57-9
4'-((2-Butyl-4-(hydroxymethyl)-5-chloro-1H-imidazolyl)methyl)-2',6'-dimethoxy(1,1'-biphenyl)-2-carboxylic acid
CAS 134360-57-9C24H27ClN2O5
4'-((2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazolyl)methyl)-2',6'-dimethoxy(1,1'-biphenyl)-2-carboxylic acid chemical structure, C24H27ClN2O5, CAS 134388-43-5
4'-((2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazolyl)methyl)-2',6'-dimethoxy(1,1'-biphenyl)-2-carboxylic acid
CAS 134388-43-5C24H27ClN2O5
Exp 597 chemical structure, C28H34FN3O6S, CAS 157566-60-4
Exp 597
CAS 157566-60-4C28H34FN3O6S
Exp 9654 chemical structure, C22H19ClN2O3, CAS 129722-03-8
Exp 9654
CAS 129722-03-8C22H19ClN2O3
Fonsartan free acid chemical structure, C26H32N4O5S2, CAS 144628-52-4
Fonsartan free acid
CAS 144628-52-4C26H32N4O5S2
2-[4-[[2-[(E)-But-1-enyl]-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzoic acid chemical structure, C22H21ClN2O3, CAS 114798-32-2
2-[4-[[2-[(E)-But-1-enyl]-4-chloro-5-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]benzoic acid
CAS 114798-32-2C22H21ClN2O3
1-(2''-Carboxy-biphenyl-4-ylmethyl)-2-propyl-1H-imidazole-4-carboxylic acid chemical structure, C21H20N2O4, CAS 172875-99-9
1-(2''-Carboxy-biphenyl-4-ylmethyl)-2-propyl-1H-imidazole-4-carboxylic acid
CAS 172875-99-9C21H20N2O4
3-[[4-(2-Carboxyphenyl)phenyl]methyl]-2-ethyl-5-(2-hydroxypropan-2-yl)imidazole-4-carboxylic acid chemical structure, C23H24N2O5, CAS 144689-67-8
3-[[4-(2-Carboxyphenyl)phenyl]methyl]-2-ethyl-5-(2-hydroxypropan-2-yl)imidazole-4-carboxylic acid
CAS 144689-67-8C23H24N2O5
Fonsartan chemical structure, C26H30K2N4O5S2, CAS 153235-15-5
Fonsartan
CAS 153235-15-5C26H30K2N4O5S2
1-(Biphenyl-4-ylmethyl)-1H-imidazole chemical structure, C16H14N2, CAS 56643-79-9
1-(Biphenyl-4-ylmethyl)-1H-imidazole
CAS 56643-79-9C16H14N2
4'-((2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)(1,1'-biphenyl)-2-carbonitrile chemical structure, C22H22ClN3O, CAS 114772-55-3
4'-((2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)(1,1'-biphenyl)-2-carbonitrile
CAS 114772-55-3C22H22ClN3O
Ethyl 1-((2'-cyano(1,1'-biphenyl)-4-yl)methyl)-4-(1-hydroxy-1-methylethyl)-2-propyl-1H-imidazole-5-carboxylate chemical structure, C26H29N3O3, CAS 144690-96-0
Ethyl 1-((2'-cyano(1,1'-biphenyl)-4-yl)methyl)-4-(1-hydroxy-1-methylethyl)-2-propyl-1H-imidazole-5-carboxylate
CAS 144690-96-0C26H29N3O3
2-[4-[[5-(Acetyloxymethyl)-2-butyl-4-chloroimidazol-1-yl]methyl]phenyl]benzoic acid chemical structure, C24H25ClN2O4, CAS 114799-14-3
2-[4-[[5-(Acetyloxymethyl)-2-butyl-4-chloroimidazol-1-yl]methyl]phenyl]benzoic acid
CAS 114799-14-3C24H25ClN2O4
1-(2'-Carbomethoxybiphenyl-4-yl)methyl-2-butyl-4-chloroimidazole-5-carboxaldehyde chemical structure, C23H23ClN2O3, CAS 114772-66-6
1-(2'-Carbomethoxybiphenyl-4-yl)methyl-2-butyl-4-chloroimidazole-5-carboxaldehyde
CAS 114772-66-6C23H23ClN2O3
2-[4-(1H-Imidazol-1-ylmethyl)phenyl]benzonitrile chemical structure, C17H13N3, CAS 929973-09-1
2-[4-(1H-Imidazol-1-ylmethyl)phenyl]benzonitrile
CAS 929973-09-1C17H13N3
(2-{4-[(1H-Imidazol-1-yl)methyl]phenyl}phenyl)methanamine chemical structure, C17H17N3, CAS 926237-60-7
(2-{4-[(1H-Imidazol-1-yl)methyl]phenyl}phenyl)methanamine
CAS 926237-60-7C17H17N3
2-[4-(1H-Imidazol-1-ylmethyl)phenyl]benzoic acid chemical structure, C17H14N2O2, CAS 929972-79-2
2-[4-(1H-Imidazol-1-ylmethyl)phenyl]benzoic acid
CAS 929972-79-2C17H14N2O2
1-(2'-Cyanobiphenyl-4-yl)methyl-4-(1-hydroxy-1-methylethyl)-2-propylimidazole-5-carboxylic acid chemical structure, C24H25N3O3, CAS 1199807-52-7
1-(2'-Cyanobiphenyl-4-yl)methyl-4-(1-hydroxy-1-methylethyl)-2-propylimidazole-5-carboxylic acid
CAS 1199807-52-7C24H25N3O3
2-[4-[[2-Butyl-4-chloro-5-(chloromethyl)imidazol-1-yl]methyl]phenyl]benzonitrile chemical structure, C22H21Cl2N3, CAS 757149-84-1
2-[4-[[2-Butyl-4-chloro-5-(chloromethyl)imidazol-1-yl]methyl]phenyl]benzonitrile
CAS 757149-84-1C22H21Cl2N3
Losartan impurity 29 chemical structure, C22H22ClN3O, CAS 2204369-11-7
Losartan impurity 29
CAS 2204369-11-7C22H22ClN3O
2-(4-((2-Butyl-4-chloro-5-formylimidazol-1-yl)methyl)phenyl)benzonitrile chemical structure, C22H20ClN3O, CAS 124750-67-0
2-(4-((2-Butyl-4-chloro-5-formylimidazol-1-yl)methyl)phenyl)benzonitrile
CAS 124750-67-0C22H20ClN3O
[4'-(1H-Imidazol-1-ylmethyl)-4-biphenylyl]methanol chemical structure, C17H16N2O, CAS 1125430-44-5
[4'-(1H-Imidazol-1-ylmethyl)-4-biphenylyl]methanol
CAS 1125430-44-5C17H16N2O
4'-{2-Ethoxy-4-ethyl-5-[((S)-2-mercapto-4-methylpentanoylamino)methyl]imidazol-1-ylmethyl}-3'-fluorobiphenyl-2-carboxylic Acid chemical structure, C28H34FN3O4S, CAS 1073549-10-6
4'-{2-Ethoxy-4-ethyl-5-[((S)-2-mercapto-4-methylpentanoylamino)methyl]imidazol-1-ylmethyl}-3'-fluorobiphenyl-2-carboxylic Acid
CAS 1073549-10-6C28H34FN3O4S