CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 20 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
18
With full pages
5
Scaffold SMILES

O=S(=O)(c1cn[nH]c1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1cn[nH]c1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

1-(5-Chloro-2-methylphenyl)-4-(1-ethylpyrazol-4-yl)sulfonylpiperazine chemical structure, C16H21ClN4O2S, CAS 898063-46-2
1-(5-Chloro-2-methylphenyl)-4-(1-ethylpyrazol-4-yl)sulfonylpiperazine
CAS 898063-46-2C16H21ClN4O2S
1-(1,3-Dimethylpyrazol-4-yl)sulfonyl-4-phenylpiperazine chemical structure, C15H20N4O2S, CAS 897451-26-2
1-(1,3-Dimethylpyrazol-4-yl)sulfonyl-4-phenylpiperazine
CAS 897451-26-2C15H20N4O2S
1-(4-Chlorophenyl)-4-(1-ethylpyrazol-4-yl)sulfonylpiperazine chemical structure, C15H19ClN4O2S, CAS 897450-84-9
1-(4-Chlorophenyl)-4-(1-ethylpyrazol-4-yl)sulfonylpiperazine
CAS 897450-84-9C15H19ClN4O2S
1-[(1,3-Dimethyl-1H-pyrazol-4-yl)sulfonyl]-4-(2-fluorophenyl)piperazine chemical structure, C15H19FN4O2S, CAS 898064-76-1
1-[(1,3-Dimethyl-1H-pyrazol-4-yl)sulfonyl]-4-(2-fluorophenyl)piperazine
CAS 898064-76-1C15H19FN4O2S
1-(1-Ethylpyrazol-4-yl)sulfonyl-4-(2-methoxyphenyl)piperazine chemical structure, C16H22N4O3S, CAS 898084-18-9
1-(1-Ethylpyrazol-4-yl)sulfonyl-4-(2-methoxyphenyl)piperazine
CAS 898084-18-9C16H22N4O3S
1-(1-Ethyl-5-methylpyrazol-4-yl)sulfonyl-4-(3-methoxyphenyl)piperazine chemical structure, C17H24N4O3S, CAS 898084-53-2
1-(1-Ethyl-5-methylpyrazol-4-yl)sulfonyl-4-(3-methoxyphenyl)piperazine
CAS 898084-53-2C17H24N4O3S
1-(1,3-Dimethylpyrazol-4-yl)sulfonyl-4-[3-(trifluoromethyl)phenyl]piperazine chemical structure, C16H19F3N4O2S, CAS 898064-09-0
1-(1,3-Dimethylpyrazol-4-yl)sulfonyl-4-[3-(trifluoromethyl)phenyl]piperazine
CAS 898064-09-0C16H19F3N4O2S
1-(3-Chlorophenyl)-4-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)piperazine chemical structure, C15H19ClN4O2S, CAS 898060-31-6
1-(3-Chlorophenyl)-4-((1,3-dimethyl-1H-pyrazol-4-yl)sulfonyl)piperazine
CAS 898060-31-6C15H19ClN4O2S
1-(3-Chlorophenyl)-4-(1-ethylpyrazol-4-yl)sulfonylpiperazine chemical structure, C15H19ClN4O2S, CAS 898060-23-6
1-(3-Chlorophenyl)-4-(1-ethylpyrazol-4-yl)sulfonylpiperazine
CAS 898060-23-6C15H19ClN4O2S
1-(1-Ethylpyrazol-4-yl)sulfonyl-4-phenylpiperazine chemical structure, C15H20N4O2S, CAS 897451-34-2
1-(1-Ethylpyrazol-4-yl)sulfonyl-4-phenylpiperazine
CAS 897451-34-2C15H20N4O2S
1-((1,3-Dimethyl-1H-pyrazol-4-yl)sulfonyl)-4-(4-methoxyphenyl)piperazine chemical structure, C16H22N4O3S, CAS 898060-68-9
1-((1,3-Dimethyl-1H-pyrazol-4-yl)sulfonyl)-4-(4-methoxyphenyl)piperazine
CAS 898060-68-9C16H22N4O3S
4-(1-Ethylpyrazol-4-yl)sulfonyl-2-methyl-1-(4-methylphenyl)piperazine chemical structure, C17H24N4O2S, CAS 898082-49-0
4-(1-Ethylpyrazol-4-yl)sulfonyl-2-methyl-1-(4-methylphenyl)piperazine
CAS 898082-49-0C17H24N4O2S
1-(1-Ethylpyrazol-4-yl)sulfonyl-4-(2-fluorophenyl)piperazine chemical structure, C15H19FN4O2S, CAS 898064-88-5
1-(1-Ethylpyrazol-4-yl)sulfonyl-4-(2-fluorophenyl)piperazine
CAS 898064-88-5C15H19FN4O2S
1-(1-Ethylpyrazol-4-yl)sulfonyl-4-[3-(trifluoromethyl)phenyl]piperazine chemical structure, C16H19F3N4O2S, CAS 898063-91-7
1-(1-Ethylpyrazol-4-yl)sulfonyl-4-[3-(trifluoromethyl)phenyl]piperazine
CAS 898063-91-7C16H19F3N4O2S
1-Acetyl-4-{4-[(1,3-dimethylpyrazol-4-yl)sulfonyl]piperazinyl}benzene chemical structure, C17H22N4O3S, CAS 1005879-43-5
1-Acetyl-4-{4-[(1,3-dimethylpyrazol-4-yl)sulfonyl]piperazinyl}benzene
CAS 1005879-43-5C17H22N4O3S
1-(3,4-Dichlorophenyl)-4-((1-ethyl-5-fluoro-3-methyl-1H-pyrazol-4-yl)sulfonyl)piperazine chemical structure, C16H19Cl2FN4O2S, CAS 1855890-22-0
1-(3,4-Dichlorophenyl)-4-((1-ethyl-5-fluoro-3-methyl-1H-pyrazol-4-yl)sulfonyl)piperazine
CAS 1855890-22-0C16H19Cl2FN4O2S
1-((1-Ethyl-5-fluoro-1H-pyrazol-4-yl)sulfonyl)-4-(4-fluorophenyl)piperazine chemical structure, C15H18F2N4O2S, CAS 1855890-73-1
1-((1-Ethyl-5-fluoro-1H-pyrazol-4-yl)sulfonyl)-4-(4-fluorophenyl)piperazine
CAS 1855890-73-1C15H18F2N4O2S
1-((1-Ethyl-5-fluoro-1H-pyrazol-4-yl)sulfonyl)-4-(4-methoxyphenyl)piperazine chemical structure, C16H21FN4O3S, CAS 1855906-78-3
1-((1-Ethyl-5-fluoro-1H-pyrazol-4-yl)sulfonyl)-4-(4-methoxyphenyl)piperazine
CAS 1855906-78-3C16H21FN4O3S