CompoundList
Murcko scaffold

2-Furyl 4-phenylpiperazinyl ketone scaffold

56 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
56
With full pages
12
Scaffold SMILES

O=C(c1ccco1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Murcko scaffold O=C(c1ccco1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 56 chemicals

1-(2-Furoyl)-4-(2-methoxyphenyl)piperazine chemical structure, C16H18N2O3, CAS 5272-56-0
1-(2-Furoyl)-4-(2-methoxyphenyl)piperazine
CAS 5272-56-0C16H18N2O3
[4-(3-Chlorophenyl)piperazin-1-yl]-(furan-2-yl)methanone chemical structure, C15H15ClN2O2, CAS 346699-56-7
[4-(3-Chlorophenyl)piperazin-1-yl]-(furan-2-yl)methanone
CAS 346699-56-7C15H15ClN2O2
(5-Bromofuran-2-yl)-(4-phenylpiperazin-1-yl)methanone chemical structure, C15H15BrN2O2, CAS 157642-11-0
(5-Bromofuran-2-yl)-(4-phenylpiperazin-1-yl)methanone
CAS 157642-11-0C15H15BrN2O2
[4-(2-Fluorophenyl)piperazin-1-yl]-(furan-2-yl)methanone chemical structure, C15H15FN2O2, CAS 432507-97-6
[4-(2-Fluorophenyl)piperazin-1-yl]-(furan-2-yl)methanone
CAS 432507-97-6C15H15FN2O2
4-(4-Fluorophenyl)piperazinyl 2-furyl ketone chemical structure, C15H15FN2O2, CAS 329219-13-8
4-(4-Fluorophenyl)piperazinyl 2-furyl ketone
CAS 329219-13-8C15H15FN2O2
[4-(4-Fluorophenyl)piperazin-1-yl]-(5-nitrofuran-2-yl)methanone chemical structure, C15H14FN3O4, CAS 69147-08-6
[4-(4-Fluorophenyl)piperazin-1-yl]-(5-nitrofuran-2-yl)methanone
CAS 69147-08-6C15H14FN3O4
2-Furyl 4-phenylpiperazinyl ketone chemical structure, C15H16N2O2, CAS 346663-77-2
2-Furyl 4-phenylpiperazinyl ketone
CAS 346663-77-2C15H16N2O2
1-(5-Methyl-2-furoyl)-4-phenylpiperazine chemical structure, C16H18N2O2, CAS 321533-32-8
1-(5-Methyl-2-furoyl)-4-phenylpiperazine
CAS 321533-32-8C16H18N2O2
1-(4-Fluorophenyl)-4-(5-methyl-2-furoyl)piperazine chemical structure, C16H17FN2O2, CAS 544431-85-8
1-(4-Fluorophenyl)-4-(5-methyl-2-furoyl)piperazine
CAS 544431-85-8C16H17FN2O2
1-(5-Methyl-2-furoyl)-4-[3-(trifluoromethyl)phenyl]piperazine chemical structure, C17H17F3N2O2, CAS 546079-88-3
1-(5-Methyl-2-furoyl)-4-[3-(trifluoromethyl)phenyl]piperazine
CAS 546079-88-3C17H17F3N2O2
Piperazine, 1-(4-aminophenyl)-4-(2-furanylcarbonyl)- chemical structure, C15H17N3O2, CAS 262375-98-4
Piperazine, 1-(4-aminophenyl)-4-(2-furanylcarbonyl)-
CAS 262375-98-4C15H17N3O2
1-(5-Bromo-2-furoyl)-4-(4-chlorophenyl)piperazine chemical structure, C15H14BrClN2O2, CAS 352678-25-2
1-(5-Bromo-2-furoyl)-4-(4-chlorophenyl)piperazine
CAS 352678-25-2C15H14BrClN2O2
1-(5-Bromo-2-furoyl)-4-(2-fluorophenyl)piperazine chemical structure, C15H14BrFN2O2, CAS 519035-92-8
1-(5-Bromo-2-furoyl)-4-(2-fluorophenyl)piperazine
CAS 519035-92-8C15H14BrFN2O2
{3-Chloro-4-[4-(2-furoyl)piperazin-1-yl]phenyl}amine chemical structure, C15H16ClN3O2, CAS 757206-87-4
{3-Chloro-4-[4-(2-furoyl)piperazin-1-yl]phenyl}amine
CAS 757206-87-4C15H16ClN3O2
[4-(4-Fluorophenyl)piperazin-1-yl](5-iodofuran-2-yl)methanone chemical structure, C15H14FIN2O2, CAS 505060-67-3
[4-(4-Fluorophenyl)piperazin-1-yl](5-iodofuran-2-yl)methanone
CAS 505060-67-3C15H14FIN2O2
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]hexanamide chemical structure, C21H27N3O3, CAS 672945-30-1
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]hexanamide
CAS 672945-30-1C21H27N3O3
N-[[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]carbamothioyl]pentanamide chemical structure, C21H26N4O3S, CAS 833436-31-0
N-[[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]carbamothioyl]pentanamide
CAS 833436-31-0C21H26N4O3S
Furan-2-yl-[4-(4-nitrophenyl)piperazin-1-yl]methanone chemical structure, C15H15N3O4, CAS 262375-97-3
Furan-2-yl-[4-(4-nitrophenyl)piperazin-1-yl]methanone
CAS 262375-97-3C15H15N3O4
(5-Bromofuran-2-yl)-[4-(4-nitrophenyl)piperazin-1-yl]methanone chemical structure, C15H14BrN3O4, CAS 362482-17-5
(5-Bromofuran-2-yl)-[4-(4-nitrophenyl)piperazin-1-yl]methanone
CAS 362482-17-5C15H14BrN3O4
RefChem:381284 chemical structure, C16H17N3O4, CAS 5712-99-2
RefChem:381284
CAS 5712-99-2C16H17N3O4
[4-(2-Chloro-4-nitrophenyl)piperazin-1-yl](5-nitrofuran-2-yl)methanone chemical structure, C15H13ClN4O6, CAS 6015-86-7
[4-(2-Chloro-4-nitrophenyl)piperazin-1-yl](5-nitrofuran-2-yl)methanone
CAS 6015-86-7C15H13ClN4O6
[4-(4-Chloro-2-nitrophenyl)piperazin-1-yl](furan-2-yl)methanone chemical structure, C15H14ClN3O4, CAS 672323-10-3
[4-(4-Chloro-2-nitrophenyl)piperazin-1-yl](furan-2-yl)methanone
CAS 672323-10-3C15H14ClN3O4
[5-(3-Hydroxy-3-methylbut-1-ynyl)furan-2-yl]-[4-(4-nitrophenyl)piperazin-1-yl]methanone chemical structure, C20H21N3O5, CAS 389137-99-9
[5-(3-Hydroxy-3-methylbut-1-ynyl)furan-2-yl]-[4-(4-nitrophenyl)piperazin-1-yl]methanone
CAS 389137-99-9C20H21N3O5
[4-(2-Chloro-6-nitrophenyl)piperazin-1-yl]-(furan-2-yl)methanone chemical structure, C15H14ClN3O4, CAS 432512-97-5
[4-(2-Chloro-6-nitrophenyl)piperazin-1-yl]-(furan-2-yl)methanone
CAS 432512-97-5C15H14ClN3O4