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Murcko scaffold

2,6-Dioxa-9-azaspiro[4.5]decane scaffold

106 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
106
With full pages
8
Scaffold SMILES

C1COC2(CCOC2)CN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,6-Dioxa-9-azaspiro[4.5]decane page
Murcko scaffold C1COC2(CCOC2)CN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 106 chemicals

2,6-Dioxa-9-azaspiro[4.5]decane chemical structure, C7H13NO2, CAS 923277-59-2
2,6-Dioxa-9-azaspiro[4.5]decane
CAS 923277-59-2C7H13NO2
7-Methyl-2,6-dioxa-9-azaspiro(4.5)decane chemical structure, C8H15NO2, CAS 1493588-45-6
7-Methyl-2,6-dioxa-9-azaspiro(4.5)decane
CAS 1493588-45-6C8H15NO2
7-Ethyl-2,6-dioxa-9-azaspiro[4.5]decane chemical structure, C9H17NO2, CAS 1488303-26-9
7-Ethyl-2,6-dioxa-9-azaspiro[4.5]decane
CAS 1488303-26-9C9H17NO2
7,7-Dimethyl-2,6-dioxa-9-azaspiro[4.5]decane chemical structure, C9H17NO2, CAS 1486752-76-4
7,7-Dimethyl-2,6-dioxa-9-azaspiro[4.5]decane
CAS 1486752-76-4C9H17NO2
9-(tert-Butoxycarbonyl)-2,6-dioxa-9-azaspiro[4.5]decane-3-carboxylic acid chemical structure, C13H21NO6, CAS 1250991-42-4
9-(tert-Butoxycarbonyl)-2,6-dioxa-9-azaspiro[4.5]decane-3-carboxylic acid
CAS 1250991-42-4C13H21NO6
tert-Butyl 3-(aminomethyl)-2,6-dioxa-9-azaspiro[4.5]decane-9-carboxylate chemical structure, C13H24N2O4, CAS 1330763-24-0
tert-Butyl 3-(aminomethyl)-2,6-dioxa-9-azaspiro[4.5]decane-9-carboxylate
CAS 1330763-24-0C13H24N2O4
1-Methyl-2,6-dioxa-9-azaspiro(4.5)decane chemical structure, C8H15NO2, CAS 1548239-15-1
1-Methyl-2,6-dioxa-9-azaspiro(4.5)decane
CAS 1548239-15-1C8H15NO2
1,7-Dimethyl-2,6-dioxa-9-azaspiro[4.5]decane chemical structure, C9H17NO2, CAS 1544360-60-2
1,7-Dimethyl-2,6-dioxa-9-azaspiro[4.5]decane
CAS 1544360-60-2C9H17NO2
8-Methyl-2,6-dioxa-9-azaspiro[4.5]decane chemical structure, C8H15NO2, CAS 1553622-23-3
8-Methyl-2,6-dioxa-9-azaspiro[4.5]decane
CAS 1553622-23-3C8H15NO2
tert-Butyl 3-(hydroxymethyl)-2,6-dioxa-9-azaspiro[4.5]decane-9-carboxylate chemical structure, C13H23NO5, CAS 1330763-25-1
tert-Butyl 3-(hydroxymethyl)-2,6-dioxa-9-azaspiro[4.5]decane-9-carboxylate
CAS 1330763-25-1C13H23NO5
(S)-2,6-Dioxa-9-azaspiro[4.5]decane chemical structure, C7H13NO2, CAS 2381280-20-0
(S)-2,6-Dioxa-9-azaspiro[4.5]decane
CAS 2381280-20-0C7H13NO2
(5R)-2,6-Dioxa-9-azaspiro[4.5]decane chemical structure, C7H13NO2, CAS 2382202-76-6
(5R)-2,6-Dioxa-9-azaspiro[4.5]decane
CAS 2382202-76-6C7H13NO2
1,1-Dimethyl-2,6-dioxa-9-azaspiro[4.5]decane chemical structure, C9H17NO2, CAS 1870766-10-1
1,1-Dimethyl-2,6-dioxa-9-azaspiro[4.5]decane
CAS 1870766-10-1C9H17NO2
2-(2,6-Dioxa-9-azaspiro(4.5)decan-9-yl)ethan-1-amine chemical structure, C9H18N2O2, CAS 1854376-05-8
2-(2,6-Dioxa-9-azaspiro(4.5)decan-9-yl)ethan-1-amine
CAS 1854376-05-8C9H18N2O2
3,3-Dimethyl-2,6-dioxa-9-azaspiro[4.5]decane chemical structure, C9H17NO2, CAS 1934368-42-9
3,3-Dimethyl-2,6-dioxa-9-azaspiro[4.5]decane
CAS 1934368-42-9C9H17NO2
2,6-Dioxa-9-aza-spiro[4.5]decane hydrochloride chemical structure, C7H14ClNO2, CAS 2177263-79-3
2,6-Dioxa-9-aza-spiro[4.5]decane hydrochloride
CAS 2177263-79-3C7H14ClNO2
1-(2,6-Dioxa-9-azaspiro[4.5]decan-9-yl)prop-2-en-1-one chemical structure, C10H15NO3, CAS 2189893-81-8
1-(2,6-Dioxa-9-azaspiro[4.5]decan-9-yl)prop-2-en-1-one
CAS 2189893-81-8C10H15NO3
1-(7,7-Dimethyl-2,6-dioxa-9-azaspiro[4.5]decan-9-yl)prop-2-en-1-one chemical structure, C12H19NO3, CAS 2187469-65-2
1-(7,7-Dimethyl-2,6-dioxa-9-azaspiro[4.5]decan-9-yl)prop-2-en-1-one
CAS 2187469-65-2C12H19NO3
1-(1-Methyl-2,6-dioxa-9-azaspiro[4.5]decan-9-yl)prop-2-en-1-one chemical structure, C11H17NO3, CAS 2224251-49-2
1-(1-Methyl-2,6-dioxa-9-azaspiro[4.5]decan-9-yl)prop-2-en-1-one
CAS 2224251-49-2C11H17NO3
1-{1,7-Dimethyl-2,6-dioxa-9-azaspiro[4.5]decan-9-yl}prop-2-en-1-one chemical structure, C12H19NO3, CAS 2224532-83-4
1-{1,7-Dimethyl-2,6-dioxa-9-azaspiro[4.5]decan-9-yl}prop-2-en-1-one
CAS 2224532-83-4C12H19NO3
1-(7-Ethyl-2,6-dioxa-9-azaspiro[4.5]decan-9-yl)prop-2-en-1-one chemical structure, C12H19NO3, CAS 2224545-04-2
1-(7-Ethyl-2,6-dioxa-9-azaspiro[4.5]decan-9-yl)prop-2-en-1-one
CAS 2224545-04-2C12H19NO3
9-(2-Ethenylsulfonylethyl)-1-methyl-2,6-dioxa-9-azaspiro[4.5]decane chemical structure, C12H21NO4S, CAS 2224268-75-9
9-(2-Ethenylsulfonylethyl)-1-methyl-2,6-dioxa-9-azaspiro[4.5]decane
CAS 2224268-75-9C12H21NO4S
9-[2-(Ethenesulfonyl)ethyl]-7-ethyl-2,6-dioxa-9-azaspiro[4.5]decane chemical structure, C13H23NO4S, CAS 2248885-46-1
9-[2-(Ethenesulfonyl)ethyl]-7-ethyl-2,6-dioxa-9-azaspiro[4.5]decane
CAS 2248885-46-1C13H23NO4S
9-(2-Ethenylsulfonylethyl)-1,7-dimethyl-2,6-dioxa-9-azaspiro[4.5]decane chemical structure, C13H23NO4S, CAS 2249258-74-8
9-(2-Ethenylsulfonylethyl)-1,7-dimethyl-2,6-dioxa-9-azaspiro[4.5]decane
CAS 2249258-74-8C13H23NO4S