Murcko scaffold
Ring system with 3 rings and 23 atoms
82 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 23
- Chemicals
- 82
- With full pages
- 8
Scaffold SMILES
O=C(NC(=S)Nc1ccccc1)c1ccc(-c2ccccc2)o1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 82 chemicals
![5-(4-Chlorophenyl)-N-[(4-propan-2-ylphenyl)carbamothioyl]furan-2-carboxamide chemical structure, C21H19ClN2O2S, CAS 445418-52-0](/s/CACQONRMIMARFI-UHFFFAOYSA-N.svg)
5-(4-Chlorophenyl)-N-[(4-propan-2-ylphenyl)carbamothioyl]furan-2-carboxamide
CAS 445418-52-0C21H19ClN2O2S
![5-(4-Chlorophenyl)-N-[(2-hydroxy-4-methylphenyl)carbamothioyl]furan-2-carboxamide chemical structure, C19H15ClN2O3S, CAS 364596-77-0](/s/KWZVCVLXTVLJFJ-UHFFFAOYSA-N.svg)
5-(4-Chlorophenyl)-N-[(2-hydroxy-4-methylphenyl)carbamothioyl]furan-2-carboxamide
CAS 364596-77-0C19H15ClN2O3S
![5-(2,5-Dichlorophenyl)-N-[[4-(2-methylpropanoylamino)phenyl]carbamothioyl]furan-2-carboxamide chemical structure, C22H19Cl2N3O3S, CAS 640757-71-7](/s/RGKLNLXCSXDDAP-UHFFFAOYSA-N.svg)
5-(2,5-Dichlorophenyl)-N-[[4-(2-methylpropanoylamino)phenyl]carbamothioyl]furan-2-carboxamide
CAS 640757-71-7C22H19Cl2N3O3S
![N-[(2-Carbamoylphenyl)carbamothioyl]-5-(3-chlorophenyl)furan-2-carboxamide chemical structure, C19H14ClN3O3S, CAS 531519-70-7](/s/FSQPISIAKGJJHQ-UHFFFAOYSA-N.svg)
N-[(2-Carbamoylphenyl)carbamothioyl]-5-(3-chlorophenyl)furan-2-carboxamide
CAS 531519-70-7C19H14ClN3O3S
![5-(4-Chlorophenyl)-N-[[2-chloro-5-(propanoylamino)phenyl]carbamothioyl]furan-2-carboxamide chemical structure, C21H17Cl2N3O3S, CAS 694443-62-4](/s/AWHRLEHQZZXMQJ-UHFFFAOYSA-N.svg)
5-(4-Chlorophenyl)-N-[[2-chloro-5-(propanoylamino)phenyl]carbamothioyl]furan-2-carboxamide
CAS 694443-62-4C21H17Cl2N3O3S
![3-[({[5-(3-Chloro-4-methylphenyl)furan-2-yl]carbonyl}carbamothioyl)amino]-4-methylbenzoic acid chemical structure, C21H17ClN2O4S, CAS 461398-42-5](/s/WNTQNZMFRZHFET-UHFFFAOYSA-N.svg)
3-[({[5-(3-Chloro-4-methylphenyl)furan-2-yl]carbonyl}carbamothioyl)amino]-4-methylbenzoic acid
CAS 461398-42-5C21H17ClN2O4S
![3-[[5-(4-Chlorophenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid chemical structure, C19H13ClN2O4S, CAS 462603-86-7](/s/HSMZRBJFNYWGRN-UHFFFAOYSA-N.svg)
3-[[5-(4-Chlorophenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid
CAS 462603-86-7C19H13ClN2O4S
![3-[({[5-(4-Bromophenyl)furan-2-yl]carbonyl}carbamothioyl)amino]benzoic acid chemical structure, C19H13BrN2O4S, CAS 461402-58-4](/s/VFDFLLHJYRZBAK-UHFFFAOYSA-N.svg)
3-[({[5-(4-Bromophenyl)furan-2-yl]carbonyl}carbamothioyl)amino]benzoic acid
CAS 461402-58-4C19H13BrN2O4S
![5-[[[[[5-(4-Bromophenyl)-2-furanyl]carbonyl]amino]thioxomethyl]amino]-2-chloro-benzoic acid chemical structure, C19H12BrClN2O4S, CAS 535965-30-1](/s/JININBPEYKVCLV-UHFFFAOYSA-N.svg)
5-[[[[[5-(4-Bromophenyl)-2-furanyl]carbonyl]amino]thioxomethyl]amino]-2-chloro-benzoic acid
CAS 535965-30-1C19H12BrClN2O4S
![2-Chloro-4-[[5-(4-chlorophenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid chemical structure, C19H12Cl2N2O4S, CAS 531519-74-1](/s/YCRJWDXAXFCBSB-UHFFFAOYSA-N.svg)
2-Chloro-4-[[5-(4-chlorophenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid
CAS 531519-74-1C19H12Cl2N2O4S
![3-[[5-(2,5-Dichlorophenyl)furan-2-carbonyl]carbamothioylamino]-4-methoxybenzoic acid chemical structure, C20H14Cl2N2O5S, CAS 690648-99-8](/s/WUAHQBJROQODJJ-UHFFFAOYSA-N.svg)
3-[[5-(2,5-Dichlorophenyl)furan-2-carbonyl]carbamothioylamino]-4-methoxybenzoic acid
CAS 690648-99-8C20H14Cl2N2O5S
![3-[[[[[5-(4-Chlorophenyl)-2-furanyl]-oxomethyl]amino]-sulfanylidenemethyl]amino]-4-methoxybenzoic acid chemical structure, C20H15ClN2O5S, CAS 532420-23-8](/s/UHEGZSZRLPTCPP-UHFFFAOYSA-N.svg)
3-[[[[[5-(4-Chlorophenyl)-2-furanyl]-oxomethyl]amino]-sulfanylidenemethyl]amino]-4-methoxybenzoic acid
CAS 532420-23-8C20H15ClN2O5S
![4-[[5-(4-Bromophenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid chemical structure, C19H13BrN2O4S, CAS 586393-25-1](/s/HBNOSXCFGXWLCL-UHFFFAOYSA-N.svg)
4-[[5-(4-Bromophenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid
CAS 586393-25-1C19H13BrN2O4S
![2-Chloro-5-[[5-(3-chloro-4-methylphenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid chemical structure, C20H14Cl2N2O4S, CAS 433947-95-6](/s/TZJBOCCIINMEFU-UHFFFAOYSA-N.svg)
2-Chloro-5-[[5-(3-chloro-4-methylphenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid
CAS 433947-95-6C20H14Cl2N2O4S
![3-[[5-(4-Chlorophenyl)furan-2-carbonyl]carbamothioylamino]-2-methylbenzoic acid chemical structure, C20H15ClN2O4S, CAS 530148-84-6](/s/TVXBRPGFQAXSST-UHFFFAOYSA-N.svg)
3-[[5-(4-Chlorophenyl)furan-2-carbonyl]carbamothioylamino]-2-methylbenzoic acid
CAS 530148-84-6C20H15ClN2O4S
![N-[(5-tert-Butyl-2-hydroxyphenyl)carbamothioyl]-5-(4-chlorophenyl)furan-2-carboxamide chemical structure, C22H21ClN2O3S, CAS 429656-47-3](/s/BWXZPODCEAYSLC-UHFFFAOYSA-N.svg)
N-[(5-tert-Butyl-2-hydroxyphenyl)carbamothioyl]-5-(4-chlorophenyl)furan-2-carboxamide
CAS 429656-47-3C22H21ClN2O3S
![5-(4-Chlorophenyl)-N-[(2-hydroxyphenyl)carbamothioyl]furan-2-carboxamide chemical structure, C18H13ClN2O3S, CAS 430442-58-3](/s/MEHQNBBEVDBNKD-UHFFFAOYSA-N.svg)
5-(4-Chlorophenyl)-N-[(2-hydroxyphenyl)carbamothioyl]furan-2-carboxamide
CAS 430442-58-3C18H13ClN2O3S
5-(4-Chlorophenyl)-N-(phenylcarbamothioyl)furan-2-carboxamide
CAS 425374-71-6C18H13ClN2O2S
![5-(4-Chlorophenyl)-N-[(3-nitrophenyl)carbamothioyl]furan-2-carboxamide chemical structure, C18H12ClN3O4S, CAS 425410-33-9](/s/DETUCXLREIAQIE-UHFFFAOYSA-N.svg)
5-(4-Chlorophenyl)-N-[(3-nitrophenyl)carbamothioyl]furan-2-carboxamide
CAS 425410-33-9C18H12ClN3O4S
![N-[(3-Chloro-4-methoxyphenyl)carbamothioyl]-5-(4-chlorophenyl)furan-2-carboxamide chemical structure, C19H14Cl2N2O3S, CAS 425411-43-4](/s/BWWAQKMGPNSQRV-UHFFFAOYSA-N.svg)
N-[(3-Chloro-4-methoxyphenyl)carbamothioyl]-5-(4-chlorophenyl)furan-2-carboxamide
CAS 425411-43-4C19H14Cl2N2O3S
![N-[[4-Chloro-2-(trifluoromethyl)phenyl]carbamothioyl]-5-(2,3-dichlorophenyl)furan-2-carboxamide chemical structure, C19H10Cl3F3N2O2S, CAS 445418-93-9](/s/NBCINSRZNJRESB-UHFFFAOYSA-N.svg)
N-[[4-Chloro-2-(trifluoromethyl)phenyl]carbamothioyl]-5-(2,3-dichlorophenyl)furan-2-carboxamide
CAS 445418-93-9C19H10Cl3F3N2O2S
![N-[[4-(Acetylsulfamoyl)phenyl]carbamothioyl]-5-(2,3-dichlorophenyl)furan-2-carboxamide chemical structure, C20H15Cl2N3O5S2, CAS 445419-95-4](/s/AOYROAHYCDQINQ-UHFFFAOYSA-N.svg)
N-[[4-(Acetylsulfamoyl)phenyl]carbamothioyl]-5-(2,3-dichlorophenyl)furan-2-carboxamide
CAS 445419-95-4C20H15Cl2N3O5S2
![3-[({[5-(4-Bromophenyl)furan-2-yl]carbonyl}carbamothioyl)amino]-2-methylbenzoic acid chemical structure, C20H15BrN2O4S, CAS 532407-52-6](/s/OPTOFPDMGMPAAN-UHFFFAOYSA-N.svg)
3-[({[5-(4-Bromophenyl)furan-2-yl]carbonyl}carbamothioyl)amino]-2-methylbenzoic acid
CAS 532407-52-6C20H15BrN2O4S
![N-[(5-tert-Butyl-3-chloro-2-hydroxyphenyl)carbamothioyl]-5-(4-chlorophenyl)furan-2-carboxamide chemical structure, C22H20Cl2N2O3S, CAS 429651-04-7](/s/QLMZNBAKKBIGIA-UHFFFAOYSA-N.svg)
N-[(5-tert-Butyl-3-chloro-2-hydroxyphenyl)carbamothioyl]-5-(4-chlorophenyl)furan-2-carboxamide
CAS 429651-04-7C22H20Cl2N2O3S
- 5-(4-Chlorophenyl)-N-[[3-methoxy-4-(2-methylpropanoylamino)phenyl]carbamothioyl]furan-2-carboxamide689767-22-4C23H22ClN3O4S
- 5-(4-Chlorophenyl)-N-[(4-ethylphenyl)carbamothioyl]furan-2-carboxamide355412-08-7C20H17ClN2O2S
- 3-[[5-(4-Bromophenyl)furan-2-carbonyl]carbamothioylamino]-4-methylbenzoic acid461399-85-9C20H15BrN2O4S
- 5-(4-Chlorophenyl)-N-[(2-methoxyphenyl)carbamothioyl]furan-2-carboxamide425402-93-3C19H15ClN2O3S
- 5-(4-Chlorophenyl)-N-[(2-methyl-4-nitrophenyl)carbamothioyl]furan-2-carboxamide6152-68-7C19H14ClN3O4S
- 5-(4-Chlorophenyl)-N-[(4-nitrophenyl)carbamothioyl]furan-2-carboxamide425411-77-4C18H12ClN3O4S
- N-{[5-(Butan-2-yl)-2-hydroxyphenyl]carbamothioyl}-5-(4-chlorophenyl)furan-2-carboxamide429651-01-4C22H21ClN2O3S
- N-[(2,4-Dimethoxyphenyl)carbamothioyl]-5-(2-fluorophenyl)furan-2-carboxamide637738-42-2C20H17FN2O4S
- 2-[[5-(2,5-Dichlorophenyl)furan-2-carbonyl]carbamothioylamino]-3,5-diiodobenzoic acid530131-33-0C19H10Cl2I2N2O4S
- 2-[[5-(4-Chlorophenyl)furan-2-carbonyl]carbamothioylamino]-3,5-diiodobenzoic acid535944-63-9C19H11ClI2N2O4S
- 3,5-Dibromo-2-[[5-(2,5-dichlorophenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid586392-11-2C19H10Br2Cl2N2O4S
- 3,5-Dichloro-2-[[5-(4-chlorophenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid531547-58-7C19H11Cl3N2O4S
- 2-[[5-(4-Bromophenyl)furan-2-carbonyl]carbamothioylamino]-3,5-dichlorobenzoic acid535940-86-4C19H11BrCl2N2O4S
- 3,5-Dichloro-2-[[[[[5-(2,5-dichlorophenyl)-2-furanyl]carbonyl]amino]thioxomethyl]amino]-benzoic acid533921-81-2C19H10Cl4N2O4S
- 3,5-Dichloro-2-[[5-(3-nitrophenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid530134-41-9C19H11Cl2N3O6S
- 5-Chloro-2-[[[[[5-(3-chlorophenyl)-2-furanyl]carbonyl]amino]thioxomethyl]amino]-benzoic acid532406-36-3C19H12Cl2N2O4S
- 3-[[5-(3-Chlorophenyl)furan-2-carbonyl]carbamothioylamino]-4-methylbenzoic acid461403-24-7C20H15ClN2O4S
- 5-Iodo-2-[[[[[5-(3-nitrophenyl)-2-furanyl]carbonyl]amino]thioxomethyl]amino]-benzoic acid531533-54-7C19H12IN3O6S
- 5-(4-Bromophenyl)-N-[(5-butan-2-yl-2-hydroxyphenyl)carbamothioyl]furan-2-carboxamide445417-07-2C22H21BrN2O3S
- 5-Bromo-2-[[[[[5-(4-chlorophenyl)-2-furanyl]carbonyl]amino]thioxomethyl]amino]-benzoic acid532414-50-9C19H12BrClN2O4S
- 5-Bromo-2-[[[[[5-(4-bromophenyl)-2-furanyl]carbonyl]amino]thioxomethyl]amino]-benzoic acid536981-26-7C19H12Br2N2O4S
- 5-Bromo-2-[[[[[5-(3-chlorophenyl)-2-furanyl]carbonyl]amino]thioxomethyl]amino]-benzoic acid531530-54-8C19H12BrClN2O4S
- 5-Bromo-2-[[[[[5-(3-nitrophenyl)-2-furanyl]carbonyl]amino]thioxomethyl]amino]-benzoic acid530147-00-3C19H12BrN3O6S
- 2-[({[5-(2,5-Dichlorophenyl)furan-2-yl]carbonyl}carbamothioyl)amino]benzoic acid586394-38-9C19H12Cl2N2O4S
Related scaffolds
Same ring framework with different atoms or bond orders
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