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Murcko scaffold

Ring system with 3 rings and 19 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
16
With full pages
5
Scaffold SMILES

c1ccc(Oc2ncc(-c3ccccc3)cn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Oc2ncc(-c3ccccc3)cn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

5-(4-Chlorophenyl)-2-phenoxypyrimidine chemical structure, C16H11ClN2O, CAS 477890-42-9
5-(4-Chlorophenyl)-2-phenoxypyrimidine
CAS 477890-42-9C16H11ClN2O
5-(4-Chlorophenyl)-2-(4-fluorophenoxy)pyrimidine chemical structure, C16H10ClFN2O, CAS 477890-43-0
5-(4-Chlorophenyl)-2-(4-fluorophenoxy)pyrimidine
CAS 477890-43-0C16H10ClFN2O
5-(4-Chlorophenyl)-2-(2,3-dimethylphenoxy)pyrimidine chemical structure, C18H15ClN2O, CAS 477890-44-1
5-(4-Chlorophenyl)-2-(2,3-dimethylphenoxy)pyrimidine
CAS 477890-44-1C18H15ClN2O
2-(4-tert-Butylphenoxy)-5-(4-chlorophenyl)pyrimidine chemical structure, C20H19ClN2O, CAS 861208-87-9
2-(4-tert-Butylphenoxy)-5-(4-chlorophenyl)pyrimidine
CAS 861208-87-9C20H19ClN2O
5-(4-Chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyrimidine chemical structure, C17H10ClF3N2O, CAS 73221-77-9
5-(4-Chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyrimidine
CAS 73221-77-9C17H10ClF3N2O
5-(4-Chlorophenyl)-2-(3-methylphenoxy)pyrimidine chemical structure, C17H13ClN2O, CAS 477890-45-2
5-(4-Chlorophenyl)-2-(3-methylphenoxy)pyrimidine
CAS 477890-45-2C17H13ClN2O
5-(4-Chlorophenyl)-2-(2,5-dichlorophenoxy)pyrimidine chemical structure, C16H9Cl3N2O, CAS 477890-46-3
5-(4-Chlorophenyl)-2-(2,5-dichlorophenoxy)pyrimidine
CAS 477890-46-3C16H9Cl3N2O
2-(4-Chloro-2-methylphenoxy)-5-(4-chlorophenyl)pyrimidine chemical structure, C17H12Cl2N2O, CAS 478029-23-1
2-(4-Chloro-2-methylphenoxy)-5-(4-chlorophenyl)pyrimidine
CAS 478029-23-1C17H12Cl2N2O
5-(4-Chlorophenyl)-2-(4-methylphenoxy)pyrimidine chemical structure, C17H13ClN2O, CAS 477857-66-2
5-(4-Chlorophenyl)-2-(4-methylphenoxy)pyrimidine
CAS 477857-66-2C17H13ClN2O
N-[3-[5-(4-Fluorophenyl)pyrimidin-2-yl]oxyphenyl]acetamide chemical structure, C18H14FN3O2, CAS 6483-82-5
N-[3-[5-(4-Fluorophenyl)pyrimidin-2-yl]oxyphenyl]acetamide
CAS 6483-82-5C18H14FN3O2
4-(2-Phenoxypyrimidin-5-yl)benzoic acid chemical structure, C17H12N2O3, CAS 1170429-44-3
4-(2-Phenoxypyrimidin-5-yl)benzoic acid
CAS 1170429-44-3C17H12N2O3
4-[2-(3-Methoxyphenoxy)pyrimidin-5-yl]benzoic acid chemical structure, C18H14N2O4, CAS 1170248-52-8
4-[2-(3-Methoxyphenoxy)pyrimidin-5-yl]benzoic acid
CAS 1170248-52-8C18H14N2O4
3-[2-(4-Fluorophenoxy)pyrimidin-5-yl]benzoic acid chemical structure, C17H11FN2O3, CAS 1170246-65-7
3-[2-(4-Fluorophenoxy)pyrimidin-5-yl]benzoic acid
CAS 1170246-65-7C17H11FN2O3
4-[2-(4-Fluorophenoxy)pyrimidin-5-yl]benzoic acid chemical structure, C17H11FN2O3, CAS 1170612-83-5
4-[2-(4-Fluorophenoxy)pyrimidin-5-yl]benzoic acid
CAS 1170612-83-5C17H11FN2O3
3-(2-Phenoxypyrimidin-5-yl)benzoic acid chemical structure, C17H12N2O3, CAS 1172330-09-4
3-(2-Phenoxypyrimidin-5-yl)benzoic acid
CAS 1172330-09-4C17H12N2O3
4-[2-(4-Methoxyphenoxy)pyrimidin-5-yl]benzoic acid chemical structure, C18H14N2O4, CAS 1170486-88-0
4-[2-(4-Methoxyphenoxy)pyrimidin-5-yl]benzoic acid
CAS 1170486-88-0C18H14N2O4