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Murcko scaffold

Ring system with 3 rings and 22 atoms

61 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
61
With full pages
7
Scaffold SMILES

O=C(COc1ccc2ccc(=O)oc2c1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccc2ccc(=O)oc2c1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 61 chemicals

2-[(4-Methyl-2-oxo-2H-chromen-7-yl)oxy]-N-phenylacetamide chemical structure, C18H15NO4, CAS 303122-37-4
2-[(4-Methyl-2-oxo-2H-chromen-7-yl)oxy]-N-phenylacetamide
CAS 303122-37-4C18H15NO4
N-(2-Chlorophenyl)-2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetamide chemical structure, C18H14ClNO4, CAS 307526-08-5
N-(2-Chlorophenyl)-2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetamide
CAS 307526-08-5C18H14ClNO4
N-(3-Chloro-phenyl)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)-acetamide chemical structure, C18H14ClNO4, CAS 307526-09-6
N-(3-Chloro-phenyl)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)-acetamide
CAS 307526-09-6C18H14ClNO4
N-(4-Chlorophenyl)-2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetamide chemical structure, C18H14ClNO4, CAS 92955-52-7
N-(4-Chlorophenyl)-2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetamide
CAS 92955-52-7C18H14ClNO4
2-(4-Methyl-2-oxochromen-7-yl)oxy-N-(2-methylphenyl)acetamide chemical structure, C19H17NO4, CAS 92955-46-9
2-(4-Methyl-2-oxochromen-7-yl)oxy-N-(2-methylphenyl)acetamide
CAS 92955-46-9C19H17NO4
2-(4-Methyl-2-oxochromen-7-yl)oxy-N-(4-methylphenyl)acetamide chemical structure, C19H17NO4, CAS 92955-47-0
2-(4-Methyl-2-oxochromen-7-yl)oxy-N-(4-methylphenyl)acetamide
CAS 92955-47-0C19H17NO4
N-(3,4-Dimethylphenyl)-2-(4-methyl-2-oxochromen-7-yl)oxyacetamide chemical structure, C20H19NO4, CAS 429651-15-0
N-(3,4-Dimethylphenyl)-2-(4-methyl-2-oxochromen-7-yl)oxyacetamide
CAS 429651-15-0C20H19NO4
N-(2-Ethoxyphenyl)-2-(2-oxochromen-7-yl)oxyacetamide chemical structure, C19H17NO5, CAS 380539-08-2
N-(2-Ethoxyphenyl)-2-(2-oxochromen-7-yl)oxyacetamide
CAS 380539-08-2C19H17NO5
N-(4-Methoxyphenyl)-2-[(2-oxo-2H-chromen-7-yl)oxy]acetamide chemical structure, C18H15NO5, CAS 522606-00-4
N-(4-Methoxyphenyl)-2-[(2-oxo-2H-chromen-7-yl)oxy]acetamide
CAS 522606-00-4C18H15NO5
N-Phenyl-2-[(3,4,8-trimethyl-2-oxo-2H-chromen-7-yl)oxy]acetamide chemical structure, C20H19NO4, CAS 380475-34-3
N-Phenyl-2-[(3,4,8-trimethyl-2-oxo-2H-chromen-7-yl)oxy]acetamide
CAS 380475-34-3C20H19NO4
2-[[2-(4-Methyl-2-oxochromen-7-yl)oxyacetyl]amino]benzamide chemical structure, C19H16N2O5, CAS 128649-83-2
2-[[2-(4-Methyl-2-oxochromen-7-yl)oxyacetyl]amino]benzamide
CAS 128649-83-2C19H16N2O5
N-(4-Methoxyphenyl)-2-[(8-methyl-2-oxo-4-propyl-2H-chromen-7-yl)oxy]acetamide chemical structure, C22H23NO5, CAS 500204-47-7
N-(4-Methoxyphenyl)-2-[(8-methyl-2-oxo-4-propyl-2H-chromen-7-yl)oxy]acetamide
CAS 500204-47-7C22H23NO5
2-[(4-Ethyl-8-methyl-2-oxo-2H-chromen-7-yl)oxy]-N-(3-methoxyphenyl)acetamide chemical structure, C21H21NO5, CAS 379731-57-4
2-[(4-Ethyl-8-methyl-2-oxo-2H-chromen-7-yl)oxy]-N-(3-methoxyphenyl)acetamide
CAS 379731-57-4C21H21NO5
N-[4-(Diethylsulfamoyl)phenyl]-2-[(3,4-dimethyl-2-oxo-2H-chromen-7-yl)oxy]acetamide chemical structure, C23H26N2O6S, CAS 379731-46-1
N-[4-(Diethylsulfamoyl)phenyl]-2-[(3,4-dimethyl-2-oxo-2H-chromen-7-yl)oxy]acetamide
CAS 379731-46-1C23H26N2O6S
2-((6-Ethyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy)-N-(m-tolyl)acetamide chemical structure, C21H21NO4, CAS 301331-49-7
2-((6-Ethyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy)-N-(m-tolyl)acetamide
CAS 301331-49-7C21H21NO4
Ethyl 3-({[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetyl}amino)benzoate chemical structure, C21H19NO6, CAS 300827-88-7
Ethyl 3-({[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetyl}amino)benzoate
CAS 300827-88-7C21H19NO6
2-(4-Methyl-2-oxochromen-7-yl)oxy-N-(2,4,6-trimethylphenyl)acetamide chemical structure, C21H21NO4, CAS 303031-76-7
2-(4-Methyl-2-oxochromen-7-yl)oxy-N-(2,4,6-trimethylphenyl)acetamide
CAS 303031-76-7C21H21NO4
2-(4-Methyl-2-oxochromen-7-yloxy)-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C19H14F3NO4, CAS 461035-55-2
2-(4-Methyl-2-oxochromen-7-yloxy)-N-[2-(trifluoromethyl)phenyl]acetamide
CAS 461035-55-2C19H14F3NO4
N-(2-Chloro-5-(trifluoromethyl)phenyl)-2-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)acetamide chemical structure, C19H13ClF3NO4, CAS 448911-00-0
N-(2-Chloro-5-(trifluoromethyl)phenyl)-2-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)acetamide
CAS 448911-00-0C19H13ClF3NO4
N-(4-Isopropoxyphenyl)-2-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)acetamide chemical structure, C21H21NO5, CAS 370586-22-4
N-(4-Isopropoxyphenyl)-2-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)acetamide
CAS 370586-22-4C21H21NO5
2-(4-Methyl-2-oxochromen-7-yl)oxy-N-(4-sulfamoylphenyl)acetamide chemical structure, C18H16N2O6S, CAS 340694-25-9
2-(4-Methyl-2-oxochromen-7-yl)oxy-N-(4-sulfamoylphenyl)acetamide
CAS 340694-25-9C18H16N2O6S
3-(2-((4-Methyl-2-oxo-2H-chromen-7-yl)oxy)acetamido)benzoic acid chemical structure, C19H15NO6, CAS 461029-53-8
3-(2-((4-Methyl-2-oxo-2H-chromen-7-yl)oxy)acetamido)benzoic acid
CAS 461029-53-8C19H15NO6
2-[(6-Chloro-4-ethyl-2-oxo-2H-chromen-7-yl)oxy]-N-(4-chlorophenyl)acetamide chemical structure, C19H15Cl2NO4, CAS 522605-99-8
2-[(6-Chloro-4-ethyl-2-oxo-2H-chromen-7-yl)oxy]-N-(4-chlorophenyl)acetamide
CAS 522605-99-8C19H15Cl2NO4
2-Hydroxy-5-[[2-(4-methyl-2-oxochromen-7-yl)oxyacetyl]amino]benzoic acid chemical structure, C19H15NO7, CAS 461032-27-9
2-Hydroxy-5-[[2-(4-methyl-2-oxochromen-7-yl)oxyacetyl]amino]benzoic acid
CAS 461032-27-9C19H15NO7