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Murcko scaffold

5-Oxa-7-azaspiro[3.4]octan-6-one scaffold

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
10
With full pages
4
Scaffold SMILES

O=C1NCC2(CCC2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Oxa-7-azaspiro[3.4]octan-6-one page
Murcko scaffold O=C1NCC2(CCC2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

5-Oxa-7-azaspiro[3.4]octan-6-one chemical structure, C6H9NO2, CAS 27784-33-4
5-Oxa-7-azaspiro[3.4]octan-6-one
CAS 27784-33-4C6H9NO2
tert-Butyl N-(6-oxo-5-oxa-7-azaspiro(3.4)octan-2-yl)carbamate chemical structure, C11H18N2O4, CAS 2305253-13-6
tert-Butyl N-(6-oxo-5-oxa-7-azaspiro(3.4)octan-2-yl)carbamate
CAS 2305253-13-6C11H18N2O4
2-Amino-5-oxa-7-azaspiro(3.4)octan-6-one hydrochloride chemical structure, C6H11ClN2O2, CAS 2305255-87-0
2-Amino-5-oxa-7-azaspiro(3.4)octan-6-one hydrochloride
CAS 2305255-87-0C6H11ClN2O2
(2s,4s)-2-Amino-5-oxa-7-azaspiro[3.4]octan-6-one chemical structure, C6H10N2O2, CAS 2305253-27-2
(2s,4s)-2-Amino-5-oxa-7-azaspiro[3.4]octan-6-one
CAS 2305253-27-2C6H10N2O2
Lithium, 6-oxo-5-oxa-7-azaspiro[3.4]octane-8-carboxylate chemical structure, C7H8LiNO4, CAS 2361635-45-0
Lithium, 6-oxo-5-oxa-7-azaspiro[3.4]octane-8-carboxylate
CAS 2361635-45-0C7H8LiNO4
6-Oxo-5-oxa-7-azaspiro[3.4]octane-8-carboxylic acid chemical structure, C7H9NO4, CAS 2361635-09-6
6-Oxo-5-oxa-7-azaspiro[3.4]octane-8-carboxylic acid
CAS 2361635-09-6C7H9NO4
2-Chloro-N-(6-oxo-5-oxa-7-azaspiro[3.4]octan-2-yl)acetamide chemical structure, C8H11ClN2O3, CAS 2411249-76-6
2-Chloro-N-(6-oxo-5-oxa-7-azaspiro[3.4]octan-2-yl)acetamide
CAS 2411249-76-6C8H11ClN2O3
N-(6-Oxo-5-oxa-7-azaspiro[3.4]octan-2-yl)prop-2-enamide chemical structure, C9H12N2O3, CAS 2411263-40-4
N-(6-Oxo-5-oxa-7-azaspiro[3.4]octan-2-yl)prop-2-enamide
CAS 2411263-40-4C9H12N2O3
(2E)-4-(Dimethylamino)-N-{6-oxo-5-oxa-7-azaspiro[3.4]octan-2-yl}but-2-enamide chemical structure, C12H19N3O3, CAS 2411336-31-5
(2E)-4-(Dimethylamino)-N-{6-oxo-5-oxa-7-azaspiro[3.4]octan-2-yl}but-2-enamide
CAS 2411336-31-5C12H19N3O3
(2s,4s)-2-Hydroxy-5-oxa-7-azaspiro[3.4]octan-6-one chemical structure, C6H9NO3, CAS 2869877-86-9
(2s,4s)-2-Hydroxy-5-oxa-7-azaspiro[3.4]octan-6-one
CAS 2869877-86-9C6H9NO3