CompoundList
Sign in
Murcko scaffold

1-Phenylpiperazine scaffold

6,403 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
6,403
With full pages
595
Scaffold SMILES

c1ccc(N2CCNCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenylpiperazine page
Murcko scaffold c1ccc(N2CCNCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,585 to 1,632 of 6,403 chemicals

N-[4-(1-Piperazinyl)phenyl]acetamide chemical structure, C12H17N3O, CAS 116290-77-8
N-[4-(1-Piperazinyl)phenyl]acetamide
CAS 116290-77-8C12H17N3O
1-(4-(4-Methylpiperazin-1-yl)phenyl)guanidine chemical structure, C12H19N5, CAS 219132-76-0
1-(4-(4-Methylpiperazin-1-yl)phenyl)guanidine
CAS 219132-76-0C12H19N5
1-(2-Fluoro-6-methoxyphenyl)piperazine chemical structure, C11H15FN2O, CAS 113028-78-7
1-(2-Fluoro-6-methoxyphenyl)piperazine
CAS 113028-78-7C11H15FN2O
4-(4-Chlorophenyl)piperazine-1-carbohydrazide chemical structure, C11H15ClN4O, CAS 127188-41-4
4-(4-Chlorophenyl)piperazine-1-carbohydrazide
CAS 127188-41-4C11H15ClN4O
2-Bromo-1-(4-phenyl-piperazin-1-yl)-propan-1-one chemical structure, C13H17BrN2O, CAS 92018-36-5
2-Bromo-1-(4-phenyl-piperazin-1-yl)-propan-1-one
CAS 92018-36-5C13H17BrN2O
2-(4-Methylpiperazin-1-yl)phenol chemical structure, C11H16N2O, CAS 189762-98-9
2-(4-Methylpiperazin-1-yl)phenol
CAS 189762-98-9C11H16N2O
1-(4-Chloro-2-methoxyphenyl)piperazine chemical structure, C11H15ClN2O, CAS 89989-01-5
1-(4-Chloro-2-methoxyphenyl)piperazine
CAS 89989-01-5C11H15ClN2O
2-(4-Methylpiperazin-1-yl)phenylboronic acid chemical structure, C11H17BN2O2, CAS 250383-80-3
2-(4-Methylpiperazin-1-yl)phenylboronic acid
CAS 250383-80-3C11H17BN2O2
4-(3,3,4-Trimethyl-1-piperazinyl)benzenamine chemical structure, C13H21N3, CAS 915722-93-9
4-(3,3,4-Trimethyl-1-piperazinyl)benzenamine
CAS 915722-93-9C13H21N3
5-(4-Methylpiperazinyl)-2-nitrobenzenecarbonitrile chemical structure, C12H14N4O2, CAS 38943-88-3
5-(4-Methylpiperazinyl)-2-nitrobenzenecarbonitrile
CAS 38943-88-3C12H14N4O2
3-Chloro-4-(4-methylpiperazin-1-yl)aniline hydrochloride chemical structure, C11H17Cl2N3, CAS 1052538-72-3
3-Chloro-4-(4-methylpiperazin-1-yl)aniline hydrochloride
CAS 1052538-72-3C11H17Cl2N3
1-(Pentafluorophenyl)piperazine hydrochloride chemical structure, C10H10ClF5N2, CAS 1052530-86-5
1-(Pentafluorophenyl)piperazine hydrochloride
CAS 1052530-86-5C10H10ClF5N2
tert-Butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate chemical structure, C15H20FN3O4, CAS 154590-34-8
tert-Butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate
CAS 154590-34-8C15H20FN3O4
1,1-Dimethylethyl 4-(4-amino-2-fluorophenyl)-1-piperazinecarboxylate chemical structure, C15H22FN3O2, CAS 154590-35-9
1,1-Dimethylethyl 4-(4-amino-2-fluorophenyl)-1-piperazinecarboxylate
CAS 154590-35-9C15H22FN3O2
1-(4-Fluorophenyl)piperazine dihydrochloride chemical structure, C10H15Cl2FN2, CAS 64090-19-3
1-(4-Fluorophenyl)piperazine dihydrochloride
CAS 64090-19-3C10H15Cl2FN2
1-(4-Iodophenyl)piperazine hydrochloride chemical structure, C10H14ClIN2, CAS 624726-35-8
1-(4-Iodophenyl)piperazine hydrochloride
CAS 624726-35-8C10H14ClIN2
tert-Butyl 4-(2-(methoxycarbonyl)-4-nitrophenyl)piperazine-1-carboxylate chemical structure, C17H23N3O6, CAS 870703-73-4
tert-Butyl 4-(2-(methoxycarbonyl)-4-nitrophenyl)piperazine-1-carboxylate
CAS 870703-73-4C17H23N3O6
4-(Boc-piperazin-1-yl)-3-nitrobenzoic acid chemical structure, C16H21N3O6, CAS 870703-72-3
4-(Boc-piperazin-1-yl)-3-nitrobenzoic acid
CAS 870703-72-3C16H21N3O6
1-Boc-4-(2-Methoxycarbonylphenyl)piperazine chemical structure, C17H24N2O4, CAS 870703-74-5
1-Boc-4-(2-Methoxycarbonylphenyl)piperazine
CAS 870703-74-5C17H24N2O4
1-(3-Formylphenyl)piperazine chemical structure, C11H14N2O, CAS 870703-56-3
1-(3-Formylphenyl)piperazine
CAS 870703-56-3C11H14N2O
1-Boc-4-(3-(ethoxycarbonyl)phenyl)piperazine chemical structure, C18H26N2O4, CAS 261925-94-4
1-Boc-4-(3-(ethoxycarbonyl)phenyl)piperazine
CAS 261925-94-4C18H26N2O4
Methyl 3-(4-methylpiperazin-1-yl)benzoate chemical structure, C13H18N2O2, CAS 474334-89-9
Methyl 3-(4-methylpiperazin-1-yl)benzoate
CAS 474334-89-9C13H18N2O2
1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine chemical structure, C11H13FN4O4, CAS 928830-73-3
1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine
CAS 928830-73-3C11H13FN4O4
2-Chloro-1-[4-(4-chloro-2-nitrophenyl)piperazin-1-yl]ethan-1-one chemical structure, C12H13Cl2N3O3, CAS 929973-10-4
2-Chloro-1-[4-(4-chloro-2-nitrophenyl)piperazin-1-yl]ethan-1-one
CAS 929973-10-4C12H13Cl2N3O3