Murcko scaffold
6-Oxaspiro[3.4]octan-5-one scaffold
13 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 13
- With full pages
- 6
Scaffold SMILES
O=C1OCCC12CCC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 13 of 13 chemicals
6-Oxaspiro[3.4]octan-5-one
CAS 84565-26-4C7H10O2
7-Methyl-6-oxaspiro[3.4]octan-5-one
CAS 2901084-90-8C8H12O2
7-(Bromomethyl)-6-oxaspiro[3.4]octan-5-one
CAS 1803590-51-3C8H11BrO2
7-(Aminomethyl)-6-oxaspiro[3.4]octan-5-one hydrochloride
CAS 1803602-25-6C8H14ClNO2
5-Oxo-7-(trifluoromethyl)-6-oxaspiro[3.4]octane-7-carboxylic acid
CAS 2172088-20-7C9H9F3O4
5-Oxo-7-propyl-6-oxaspiro[3.4]octane-7-carboxylic acid
CAS 2171915-35-6C11H16O4
7-tert-Butyl-5-oxo-6-oxaspiro[3.4]octane-7-carboxylic acid
CAS 2172598-03-5C12H18O4
7-Ethyl-5-oxo-6-oxaspiro[3.4]octane-7-carboxylic acid
CAS 2172001-83-9C10H14O4
5-Oxo-7-(propan-2-yl)-6-oxaspiro[3.4]octane-7-carboxylic acid
CAS 2172497-06-0C11H16O4
7-(Difluoromethyl)-5-oxo-6-oxaspiro[3.4]octane-7-carboxylic acid
CAS 2172056-34-5C9H10F2O4
7-Methyl-5-oxo-6-oxaspiro[3.4]octane-7-carboxylic acid
CAS 2172517-22-3C9H12O4
8-Hydroxy-6-oxaspiro[3.4]octan-5-one
CAS 2770554-74-8C7H10O3
7-(Iodomethyl)-6-oxaspiro(3.4)octan-5-one
CAS 2901100-07-8C8H11IO2