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Murcko scaffold

N-Phenyl-2-(4-phenylphenyl)acetamide scaffold

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
20
With full pages
3
Scaffold SMILES

O=C(Cc1ccc(-c2ccccc2)cc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-2-(4-phenylphenyl)acetamide page
Murcko scaffold O=C(Cc1ccc(-c2ccccc2)cc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

N-(3-Acetylphenyl)-2-(4-phenylphenyl)acetamide chemical structure, C22H19NO2, CAS 708286-65-1
N-(3-Acetylphenyl)-2-(4-phenylphenyl)acetamide
CAS 708286-65-1C22H19NO2
N-(3-Methoxyphenyl)-2-(4-phenylphenyl)acetamide chemical structure, C21H19NO2, CAS 610266-87-0
N-(3-Methoxyphenyl)-2-(4-phenylphenyl)acetamide
CAS 610266-87-0C21H19NO2
N-(2,5-Dichlorophenyl)-2-(4-phenylphenyl)acetamide chemical structure, C20H15Cl2NO, CAS 5337-56-4
N-(2,5-Dichlorophenyl)-2-(4-phenylphenyl)acetamide
CAS 5337-56-4C20H15Cl2NO
N-(2,4-Difluorophenyl)-2-(4-phenylphenyl)acetamide chemical structure, C20H15F2NO, CAS 331435-84-8
N-(2,4-Difluorophenyl)-2-(4-phenylphenyl)acetamide
CAS 331435-84-8C20H15F2NO
N-(4-Fluorophenyl)-2-(4-phenylphenyl)acetamide chemical structure, C20H16FNO, CAS 331440-17-6
N-(4-Fluorophenyl)-2-(4-phenylphenyl)acetamide
CAS 331440-17-6C20H16FNO
2-(4-Phenylphenyl)-N-(4-propan-2-ylphenyl)acetamide chemical structure, C23H23NO, CAS 415691-38-2
2-(4-Phenylphenyl)-N-(4-propan-2-ylphenyl)acetamide
CAS 415691-38-2C23H23NO
N-(3-Fluoro-4-methylphenyl)-2-(4-phenylphenyl)acetamide chemical structure, C21H18FNO, CAS 881593-35-7
N-(3-Fluoro-4-methylphenyl)-2-(4-phenylphenyl)acetamide
CAS 881593-35-7C21H18FNO
N-(5-Chloro-2-methoxyphenyl)-2-(4-phenylphenyl)acetamide chemical structure, C21H18ClNO2, CAS 847919-69-1
N-(5-Chloro-2-methoxyphenyl)-2-(4-phenylphenyl)acetamide
CAS 847919-69-1C21H18ClNO2
N-Phenyl-2-(4-phenylphenyl)acetamide chemical structure, C20H17NO, CAS 848175-28-0
N-Phenyl-2-(4-phenylphenyl)acetamide
CAS 848175-28-0C20H17NO
N-(2-Chlorophenyl)-2-(4-phenylphenyl)acetamide chemical structure, C20H16ClNO, CAS 848286-39-5
N-(2-Chlorophenyl)-2-(4-phenylphenyl)acetamide
CAS 848286-39-5C20H16ClNO
N-(2-Methoxyphenyl)-2-(4-phenylphenyl)acetamide chemical structure, C21H19NO2, CAS 848373-60-4
N-(2-Methoxyphenyl)-2-(4-phenylphenyl)acetamide
CAS 848373-60-4C21H19NO2
N-(3-Fluorophenyl)-2-(4-phenylphenyl)acetamide chemical structure, C20H16FNO, CAS 848593-32-8
N-(3-Fluorophenyl)-2-(4-phenylphenyl)acetamide
CAS 848593-32-8C20H16FNO
N-(2-Ethoxyphenyl)-2-(4-phenylphenyl)acetamide chemical structure, C22H21NO2, CAS 924205-46-9
N-(2-Ethoxyphenyl)-2-(4-phenylphenyl)acetamide
CAS 924205-46-9C22H21NO2
2-[1,1'-Biphenyl]-4-yl-N-(2-fluorophenyl)acetamide chemical structure, C20H16FNO, CAS 879311-09-8
2-[1,1'-Biphenyl]-4-yl-N-(2-fluorophenyl)acetamide
CAS 879311-09-8C20H16FNO
2-(2-Fluoro[1,1'-biphenyl]-4-yl)-N-(4-methylphenyl)propanamide chemical structure, C22H20FNO, CAS 190125-74-7
2-(2-Fluoro[1,1'-biphenyl]-4-yl)-N-(4-methylphenyl)propanamide
CAS 190125-74-7C22H20FNO
N-(4-Chlorophenyl)-2-(2-fluoro[1,1'-biphenyl]-4-yl)propanamide chemical structure, C21H17ClFNO, CAS 190125-64-5
N-(4-Chlorophenyl)-2-(2-fluoro[1,1'-biphenyl]-4-yl)propanamide
CAS 190125-64-5C21H17ClFNO
2-(2-Fluoro[1,1'-biphenyl]-4-yl)-N-(4-methoxyphenyl)propanamide chemical structure, C22H20FNO2, CAS 190125-90-7
2-(2-Fluoro[1,1'-biphenyl]-4-yl)-N-(4-methoxyphenyl)propanamide
CAS 190125-90-7C22H20FNO2
2-[4-(2-{[1,1'-Biphenyl]-4-yl}acetamido)phenyl]-N,N-dimethylacetamide chemical structure, C24H24N2O2, CAS 1060281-74-4
2-[4-(2-{[1,1'-Biphenyl]-4-yl}acetamido)phenyl]-N,N-dimethylacetamide
CAS 1060281-74-4C24H24N2O2
2-[1,1'-Biphenyl]-4-yl-N-ethyl-N-phenylacetamide chemical structure, C22H21NO, CAS 1354488-97-3
2-[1,1'-Biphenyl]-4-yl-N-ethyl-N-phenylacetamide
CAS 1354488-97-3C22H21NO
2-([1,1'-Biphenyl]-4-yl)-N-(4-hydroxyphenyl)acetamide chemical structure, C20H17NO2, CAS 916165-60-1
2-([1,1'-Biphenyl]-4-yl)-N-(4-hydroxyphenyl)acetamide
CAS 916165-60-1C20H17NO2