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Murcko scaffold

Pyrimidine scaffold

19,000 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
19,000
With full pages
2,066
Scaffold SMILES

c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Pyrimidine page
Murcko scaffold c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,153 to 1,200 of 19,000 chemicals

2-(Allylsulfanyl)-4-amino-5-pyrimidinecarbonitrile chemical structure, C8H8N4S, CAS 664994-02-9
2-(Allylsulfanyl)-4-amino-5-pyrimidinecarbonitrile
CAS 664994-02-9C8H8N4S
2-(2-Pyrimidinylsulfanyl)acetonitrile chemical structure, C6H5N3S, CAS 74537-75-0
2-(2-Pyrimidinylsulfanyl)acetonitrile
CAS 74537-75-0C6H5N3S
Diethyl {[2-(4,6-dimethylpyrimidin-2-yl)hydrazinyl]methylidene}propanedioate chemical structure, C14H20N4O4, CAS 774562-86-6
Diethyl {[2-(4,6-dimethylpyrimidin-2-yl)hydrazinyl]methylidene}propanedioate
CAS 774562-86-6C14H20N4O4
2-[(6-Chloro-4-pyrimidinyl)amino]ethanol chemical structure, C6H8ClN3O, CAS 22177-94-2
2-[(6-Chloro-4-pyrimidinyl)amino]ethanol
CAS 22177-94-2C6H8ClN3O
Ethyl [(4,6-dimethylpyrimidin-2-yl)amino](oxo)acetate chemical structure, C10H13N3O3, CAS 349442-54-2
Ethyl [(4,6-dimethylpyrimidin-2-yl)amino](oxo)acetate
CAS 349442-54-2C10H13N3O3
Ethanol, 2-((6-chloro-2-methyl-5-(2-propenyl)-4-pyrimidinyl)amino)- chemical structure, C10H14ClN3O, CAS 85826-36-4
Ethanol, 2-((6-chloro-2-methyl-5-(2-propenyl)-4-pyrimidinyl)amino)-
CAS 85826-36-4C10H14ClN3O
2-Chloro-4-(dimethylamino)-5-fluoropyrimidine chemical structure, C6H7ClFN3, CAS 355829-23-1
2-Chloro-4-(dimethylamino)-5-fluoropyrimidine
CAS 355829-23-1C6H7ClFN3
2-[(2-Chloro-5-fluoropyrimidin-4-yl)amino]ethanol chemical structure, C6H7ClFN3O, CAS 16255-90-6
2-[(2-Chloro-5-fluoropyrimidin-4-yl)amino]ethanol
CAS 16255-90-6C6H7ClFN3O
5-Chloro-2-(ethylthio)pyrimidine-4-carboxylic acid chemical structure, C7H7ClN2O2S, CAS 382610-58-4
5-Chloro-2-(ethylthio)pyrimidine-4-carboxylic acid
CAS 382610-58-4C7H7ClN2O2S
Ethyl 4-[4-amino-5-(ethoxycarbonyl)pyrimidin-2-ylthio]-3-oxobutanoate chemical structure, C13H17N3O5S, CAS 491642-68-3
Ethyl 4-[4-amino-5-(ethoxycarbonyl)pyrimidin-2-ylthio]-3-oxobutanoate
CAS 491642-68-3C13H17N3O5S
(2E)-3-(2,4-Dimethoxy-6-methylpyrimidin-5-yl)prop-2-enoic acid chemical structure, C10H12N2O4, CAS 119840-21-0
(2E)-3-(2,4-Dimethoxy-6-methylpyrimidin-5-yl)prop-2-enoic acid
CAS 119840-21-0C10H12N2O4
4-tert-Butyl-6-(2-methoxypropan-2-yl)pyrimidin-2-amine chemical structure, C12H21N3O, CAS 5213-24-1
4-tert-Butyl-6-(2-methoxypropan-2-yl)pyrimidin-2-amine
CAS 5213-24-1C12H21N3O
2,2,3,3-Tetrafluoropropyl 5-[(2,6-dimethoxypyrimidin-4-yl)amino]-5-oxopentanoate chemical structure, C14H17F4N3O5, CAS 5576-93-2
2,2,3,3-Tetrafluoropropyl 5-[(2,6-dimethoxypyrimidin-4-yl)amino]-5-oxopentanoate
CAS 5576-93-2C14H17F4N3O5
(4,6-Dimethylpyrimidin-2-ylsulfanyl)acetic acid ethyl ester chemical structure, C10H14N2O2S, CAS 54820-01-8
(4,6-Dimethylpyrimidin-2-ylsulfanyl)acetic acid ethyl ester
CAS 54820-01-8C10H14N2O2S
4-Methyl-6-(2,2,3,3,4,4,5,5-octafluoropentoxy)pyrimidin-2-amine chemical structure, C10H9F8N3O, CAS 5483-61-4
4-Methyl-6-(2,2,3,3,4,4,5,5-octafluoropentoxy)pyrimidin-2-amine
CAS 5483-61-4C10H9F8N3O
N-tert-Butyl-2,5,6-trichloropyrimidin-4-amine chemical structure, C8H10Cl3N3, CAS 351988-37-9
N-tert-Butyl-2,5,6-trichloropyrimidin-4-amine
CAS 351988-37-9C8H10Cl3N3
Diethyl (pyrimidin-2-yl)propanedioate chemical structure, C11H14N2O4, CAS 164296-40-6
Diethyl (pyrimidin-2-yl)propanedioate
CAS 164296-40-6C11H14N2O4
2-Amino-5-methoxypyrimidine chemical structure, C5H7N3O, CAS 13418-77-4
2-Amino-5-methoxypyrimidine
CAS 13418-77-4C5H7N3O
4-Amino-5-methoxymethyl-2-methylpyrimidine chemical structure, C7H11N3O, CAS 769-82-4
4-Amino-5-methoxymethyl-2-methylpyrimidine
CAS 769-82-4C7H11N3O
Ethyl 2-(4,6-dimethylpyrimidin-2-yl)acetate chemical structure, C10H14N2O2, CAS 22114-32-5
Ethyl 2-(4,6-dimethylpyrimidin-2-yl)acetate
CAS 22114-32-5C10H14N2O2
2-(Butylamino)-5-chloropyrimidine-4-carboxylic acid chemical structure, C9H12ClN3O2, CAS 329268-86-2
2-(Butylamino)-5-chloropyrimidine-4-carboxylic acid
CAS 329268-86-2C9H12ClN3O2
2-[Butyl(methyl)amino]-5-chloropyrimidine-4-carboxylic acid chemical structure, C10H14ClN3O2, CAS 329268-85-1
2-[Butyl(methyl)amino]-5-chloropyrimidine-4-carboxylic acid
CAS 329268-85-1C10H14ClN3O2
5-Chloro-2-(diethylamino)pyrimidine-4-carboxylic acid chemical structure, C9H12ClN3O2, CAS 329268-83-9
5-Chloro-2-(diethylamino)pyrimidine-4-carboxylic acid
CAS 329268-83-9C9H12ClN3O2
Diethyl 2,2'-[(6-methylpyrimidine-2,4-diyl)disulfanediyl]diacetate chemical structure, C13H18N2O4S2, CAS 112498-42-7
Diethyl 2,2'-[(6-methylpyrimidine-2,4-diyl)disulfanediyl]diacetate
CAS 112498-42-7C13H18N2O4S2