CompoundList
Sign in
Murcko scaffold

Spiro(3.4)octan-2-one scaffold

9 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
9
With full pages
3
Scaffold SMILES

O=C1CC2(CCCC2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Spiro(3.4)octan-2-one page
Murcko scaffold O=C1CC2(CCCC2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

Spiro(3.4)octan-2-one chemical structure, C8H12O, CAS 41463-77-8
Spiro(3.4)octan-2-one
CAS 41463-77-8C8H12O
Spiro[3.4]octan-2-one, 1,1-dichloro- chemical structure, C8H10Cl2O, CAS 329187-14-6
Spiro[3.4]octan-2-one, 1,1-dichloro-
CAS 329187-14-6C8H10Cl2O
1-Ethenyl-1-methylspiro[3.4]octan-2-one chemical structure, C11H16O, CAS 89237-37-6
1-Ethenyl-1-methylspiro[3.4]octan-2-one
CAS 89237-37-6C11H16O
1-Ethenyl-1-ethylspiro[3.4]octan-2-one chemical structure, C12H18O, CAS 89237-43-4
1-Ethenyl-1-ethylspiro[3.4]octan-2-one
CAS 89237-43-4C12H18O
1-Methyl-1-(2-methylprop-1-en-1-yl)spiro[3.4]octan-2-one chemical structure, C13H20O, CAS 89609-15-4
1-Methyl-1-(2-methylprop-1-en-1-yl)spiro[3.4]octan-2-one
CAS 89609-15-4C13H20O
2-Oxospiro[3.4]octane-6-carboxylic acid chemical structure, C9H12O3, CAS 2090464-60-9
2-Oxospiro[3.4]octane-6-carboxylic acid
CAS 2090464-60-9C9H12O3
6,6-Dimethylspiro[3.4]octan-2-one chemical structure, C10H16O, CAS 2825012-59-5
6,6-Dimethylspiro[3.4]octan-2-one
CAS 2825012-59-5C10H16O
7-Methoxyspiro[3.4]octan-2-one chemical structure, C9H14O2, CAS 2920436-73-1
7-Methoxyspiro[3.4]octan-2-one
CAS 2920436-73-1C9H14O2
8-Methoxyspiro[3.4]octan-2-one chemical structure, C9H14O2, CAS 2920415-86-5
8-Methoxyspiro[3.4]octan-2-one
CAS 2920415-86-5C9H14O2