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Murcko scaffold

Ring system with 3 rings and 23 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
13
With full pages
3
Scaffold SMILES

O=C(CNc1ccccc1)N1CCC(Cc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNc1ccccc1)N1CCC(Cc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(3-chloro-2-methylphenyl)methanesulfonamide chemical structure, C22H27ClN2O3S, CAS 335212-67-4
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(3-chloro-2-methylphenyl)methanesulfonamide
CAS 335212-67-4C22H27ClN2O3S
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(3,4-dimethoxyphenyl)methanesulfonamide chemical structure, C23H30N2O5S, CAS 366832-39-5
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(3,4-dimethoxyphenyl)methanesulfonamide
CAS 366832-39-5C23H30N2O5S
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(4-ethoxyphenyl)methanesulfonamide chemical structure, C23H30N2O4S, CAS 367919-83-3
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(4-ethoxyphenyl)methanesulfonamide
CAS 367919-83-3C23H30N2O4S
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(2-fluorophenyl)methanesulfonamide chemical structure, C21H25FN2O3S, CAS 367917-32-6
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(2-fluorophenyl)methanesulfonamide
CAS 367917-32-6C21H25FN2O3S
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(3-chloro-4-methylphenyl)methanesulfonamide chemical structure, C22H27ClN2O3S, CAS 428468-87-5
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(3-chloro-4-methylphenyl)methanesulfonamide
CAS 428468-87-5C22H27ClN2O3S
N-[1-(4-Benzylpiperidin-1-yl)-1-oxopropan-2-yl]-N-(4-methoxyphenyl)methanesulfonamide chemical structure, C23H30N2O4S, CAS 1084916-22-2
N-[1-(4-Benzylpiperidin-1-yl)-1-oxopropan-2-yl]-N-(4-methoxyphenyl)methanesulfonamide
CAS 1084916-22-2C23H30N2O4S
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(3,5-dichlorophenyl)methanesulfonamide chemical structure, C21H24Cl2N2O3S, CAS 428501-15-9
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(3,5-dichlorophenyl)methanesulfonamide
CAS 428501-15-9C21H24Cl2N2O3S
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(3-fluorophenyl)methanesulfonamide chemical structure, C21H25FN2O3S, CAS 641607-47-8
N-[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-N-(3-fluorophenyl)methanesulfonamide
CAS 641607-47-8C21H25FN2O3S
1-(4-Benzylpiperidin-1-yl)-2-[N-(dimethylsulfamoyl)anilino]ethanone chemical structure, C22H29N3O3S, CAS 830353-32-7
1-(4-Benzylpiperidin-1-yl)-2-[N-(dimethylsulfamoyl)anilino]ethanone
CAS 830353-32-7C22H29N3O3S
N-Phenyl-N-[1-[[4-(phenylmethyl)-1-piperidinyl]carbonyl]propyl]methanesulfonamide chemical structure, C23H30N2O3S, CAS 1094384-64-1
N-Phenyl-N-[1-[[4-(phenylmethyl)-1-piperidinyl]carbonyl]propyl]methanesulfonamide
CAS 1094384-64-1C23H30N2O3S
[[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-(4-methoxyphenyl)amino]acetic acid chemical structure, C23H28N2O4, CAS 1142205-66-0
[[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl]-(4-methoxyphenyl)amino]acetic acid
CAS 1142205-66-0C23H28N2O4
[[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl](phenyl)-amino]acetic acid chemical structure, C22H26N2O3, CAS 1142211-81-1
[[2-(4-Benzylpiperidin-1-yl)-2-oxoethyl](phenyl)-amino]acetic acid
CAS 1142211-81-1C22H26N2O3
N-[4-[[2-[4-[(4-Fluorophenyl)methyl]-1-piperidinyl]-2-oxoethyl]amino]phenyl]methanesulfonamide chemical structure, C21H26FN3O3S, CAS 496057-60-4
N-[4-[[2-[4-[(4-Fluorophenyl)methyl]-1-piperidinyl]-2-oxoethyl]amino]phenyl]methanesulfonamide
CAS 496057-60-4C21H26FN3O3S