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Murcko scaffold

Ring system with 3 rings and 22 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
19
With full pages
4
Scaffold SMILES

O=C(CN1CCC(N2CCCCC2)CC1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN1CCC(N2CCCCC2)CC1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

CBKinase1_011059 chemical structure, C19H26ClFN4O2, CAS 717874-33-4
CBKinase1_011059
CAS 717874-33-4C19H26ClFN4O2
Methyl 4-[2-(4-carbamoyl-4-piperidylpiperidyl)acetylamino]benzoate chemical structure, C21H30N4O4, CAS 831185-35-4
Methyl 4-[2-(4-carbamoyl-4-piperidylpiperidyl)acetylamino]benzoate
CAS 831185-35-4C21H30N4O4
1'-{2-[(4-Chlorophenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide chemical structure, C19H27ClN4O2, CAS 717878-94-9
1'-{2-[(4-Chlorophenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide
CAS 717878-94-9C19H27ClN4O2
1'-{2-[(2,4-Dimethoxyphenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide chemical structure, C21H32N4O4, CAS 717828-73-4
1'-{2-[(2,4-Dimethoxyphenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide
CAS 717828-73-4C21H32N4O4
1'-{2-[(4-Methoxyphenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide chemical structure, C20H30N4O3, CAS 831206-58-7
1'-{2-[(4-Methoxyphenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide
CAS 831206-58-7C20H30N4O3
1-{[N-(4-Bromophenyl)carbamoyl]methyl}-4-piperidylpiperidine-4-carboxamide chemical structure, C19H27BrN4O2, CAS 717829-22-6
1-{[N-(4-Bromophenyl)carbamoyl]methyl}-4-piperidylpiperidine-4-carboxamide
CAS 717829-22-6C19H27BrN4O2
1-{[N-(4-Fluorophenyl)carbamoyl]methyl}-4-piperidylpiperidine-4-carboxamide chemical structure, C19H27FN4O2, CAS 831209-16-6
1-{[N-(4-Fluorophenyl)carbamoyl]methyl}-4-piperidylpiperidine-4-carboxamide
CAS 831209-16-6C19H27FN4O2
1-{[N-(2-Ethoxyphenyl)carbamoyl]methyl}-4-piperidylpiperidine-4-carboxamide chemical structure, C21H32N4O3, CAS 831234-11-8
1-{[N-(2-Ethoxyphenyl)carbamoyl]methyl}-4-piperidylpiperidine-4-carboxamide
CAS 831234-11-8C21H32N4O3
1-{[N-(4-Chloro-2-methylphenyl)carbamoyl]methyl}-4-piperidylpiperidine-4-carbo xamide chemical structure, C20H29ClN4O2, CAS 717831-29-3
1-{[N-(4-Chloro-2-methylphenyl)carbamoyl]methyl}-4-piperidylpiperidine-4-carbo xamide
CAS 717831-29-3C20H29ClN4O2
1'-{2-[(2,5-Dimethoxyphenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide chemical structure, C21H32N4O4, CAS 831236-63-6
1'-{2-[(2,5-Dimethoxyphenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide
CAS 831236-63-6C21H32N4O4
1'-{2-[(3,5-Dimethylphenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide chemical structure, C21H32N4O2, CAS 717832-26-3
1'-{2-[(3,5-Dimethylphenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide
CAS 717832-26-3C21H32N4O2
1'-{2-[(3-Chloro-2-methylphenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide chemical structure, C20H29ClN4O2, CAS 669755-70-8
1'-{2-[(3-Chloro-2-methylphenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide
CAS 669755-70-8C20H29ClN4O2
1-[(N-Phenylcarbamoyl)methyl]-4-piperidylpiperidine-4-carboxamide chemical structure, C19H28N4O2, CAS 895886-50-7
1-[(N-Phenylcarbamoyl)methyl]-4-piperidylpiperidine-4-carboxamide
CAS 895886-50-7C19H28N4O2
1-[2-(4-Chloro-2,5-dimethoxyanilino)-2-oxoethyl]-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C21H31ClN4O4, CAS 728001-15-8
1-[2-(4-Chloro-2,5-dimethoxyanilino)-2-oxoethyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 728001-15-8C21H31ClN4O4
1'-{2-[(2,5-Dichlorophenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide chemical structure, C19H26Cl2N4O2, CAS 717875-76-8
1'-{2-[(2,5-Dichlorophenyl)amino]-2-oxoethyl}-1,4'-bipiperidine-4'-carboxamide
CAS 717875-76-8C19H26Cl2N4O2
1-[2-(2-Methoxy-4-nitroanilino)-2-oxoethyl]-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C20H29N5O5, CAS 717833-14-2
1-[2-(2-Methoxy-4-nitroanilino)-2-oxoethyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 717833-14-2C20H29N5O5
Dimethyl 5-({[4'-(aminocarbonyl)-1,4'-bipiperidin-1'-yl]acetyl}amino)isophthalate chemical structure, C23H32N4O6, CAS 831247-38-2
Dimethyl 5-({[4'-(aminocarbonyl)-1,4'-bipiperidin-1'-yl]acetyl}amino)isophthalate
CAS 831247-38-2C23H32N4O6
2-{[1,4'-Bipiperidine]-1'-yl}-N-(3-methoxyphenyl)acetamide chemical structure, C19H29N3O2, CAS 2324935-06-8
2-{[1,4'-Bipiperidine]-1'-yl}-N-(3-methoxyphenyl)acetamide
CAS 2324935-06-8C19H29N3O2
2-{[1,4'-Bipiperidine]-1'-yl}-N-(3-methylphenyl)acetamide chemical structure, C19H29N3O, CAS 2327302-96-3
2-{[1,4'-Bipiperidine]-1'-yl}-N-(3-methylphenyl)acetamide
CAS 2327302-96-3C19H29N3O