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Murcko scaffold

Ring system with 3 rings and 20 atoms

105 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
105
With full pages
14
Scaffold SMILES

O=c1c(C=Nc2ccccc2)c[nH]n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(C=Nc2ccccc2)c[nH]n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 105 of 105 chemicals

Dimethyl 5-({(1Z)-1-[3-(2-methoxy-2-oxoethyl)-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene]ethyl}amino)benzene-1,3-dicarboxylate chemical structure, C24H23N3O7, CAS 884417-14-5
Dimethyl 5-({(1Z)-1-[3-(2-methoxy-2-oxoethyl)-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene]ethyl}amino)benzene-1,3-dicarboxylate
CAS 884417-14-5C24H23N3O7
Methyl 2-({(1Z)-1-[3-(2-methoxy-2-oxoethyl)-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene]ethyl}amino)benzoate chemical structure, C22H21N3O5, CAS 884417-54-3
Methyl 2-({(1Z)-1-[3-(2-methoxy-2-oxoethyl)-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene]ethyl}amino)benzoate
CAS 884417-54-3C22H21N3O5
Dimethyl 2-({(1Z)-1-[3-(2-methoxy-2-oxoethyl)-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene]ethyl}amino)benzene-1,4-dicarboxylate chemical structure, C24H23N3O7, CAS 884417-94-1
Dimethyl 2-({(1Z)-1-[3-(2-methoxy-2-oxoethyl)-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene]ethyl}amino)benzene-1,4-dicarboxylate
CAS 884417-94-1C24H23N3O7
Methyl 4,5-dimethoxy-2-({(1Z)-1-[3-(2-methoxy-2-oxoethyl)-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene]ethyl}amino)benzoate chemical structure, C24H25N3O7, CAS 884418-34-2
Methyl 4,5-dimethoxy-2-({(1Z)-1-[3-(2-methoxy-2-oxoethyl)-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene]ethyl}amino)benzoate
CAS 884418-34-2C24H25N3O7
Methyl [(4Z)-1-(4-methoxyphenyl)-5-oxo-4-(1-{[2-(trifluoromethoxy)phenyl]amino}ethylidene)-4,5-dihydro-1H-pyrazol-3-yl]acetate chemical structure, C22H20F3N3O5, CAS 884418-82-0
Methyl [(4Z)-1-(4-methoxyphenyl)-5-oxo-4-(1-{[2-(trifluoromethoxy)phenyl]amino}ethylidene)-4,5-dihydro-1H-pyrazol-3-yl]acetate
CAS 884418-82-0C22H20F3N3O5
Methyl 2-({(1Z)-1-[1-(4-fluorophenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]ethyl}amino)benzoate chemical structure, C20H18FN3O3, CAS 884398-33-8
Methyl 2-({(1Z)-1-[1-(4-fluorophenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]ethyl}amino)benzoate
CAS 884398-33-8C20H18FN3O3
Methyl 4-chloro-2-{[(E)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)methyl]amino}benzoate chemical structure, C19H16ClN3O3, CAS 929855-15-2
Methyl 4-chloro-2-{[(E)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)methyl]amino}benzoate
CAS 929855-15-2C19H16ClN3O3
4-[(5-Chloro-2-hydroxyphenyl)iminomethyl]-2-(4-chloro-3-methoxyphenyl)-5-methyl-1H-pyrazol-3-one chemical structure, C18H15Cl2N3O3, CAS 2220954-82-3
4-[(5-Chloro-2-hydroxyphenyl)iminomethyl]-2-(4-chloro-3-methoxyphenyl)-5-methyl-1H-pyrazol-3-one
CAS 2220954-82-3C18H15Cl2N3O3
Chromium(3+) sodium 3-({(e)-[3-methyl-5-oxido-1-(3-sulfonatophenyl)-1H-pyrazol-4-yl]methylidene}amino)-5-nitro-2-oxidobenzenesul chemical structure, C17H10CrN4NaO10S2
Chromium(3+) sodium 3-({(e)-[3-methyl-5-oxido-1-(3-sulfonatophenyl)-1H-pyrazol-4-yl]methylidene}amino)-5-nitro-2-oxidobenzenesul
C17H10CrN4NaO10S2