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Murcko scaffold

Ring system with 3 rings and 24 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
8
With full pages
3
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCN(CCOc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1CCN(CCOc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

1-(2-(4-Chlorophenoxy)ethyl)-4-tosylpiperazine chemical structure, C19H23ClN2O3S, CAS 327971-34-6
1-(2-(4-Chlorophenoxy)ethyl)-4-tosylpiperazine
CAS 327971-34-6C19H23ClN2O3S
N-[4-[4-[2-(4-Chlorophenoxy)ethyl]piperazin-1-yl]sulfonylphenyl]acetamide chemical structure, C20H24ClN3O4S, CAS 673497-18-2
N-[4-[4-[2-(4-Chlorophenoxy)ethyl]piperazin-1-yl]sulfonylphenyl]acetamide
CAS 673497-18-2C20H24ClN3O4S
1-(Benzenesulfonyl)-4-[2-(4-chlorophenoxy)ethyl]piperazine chemical structure, C18H21ClN2O3S, CAS 662164-43-4
1-(Benzenesulfonyl)-4-[2-(4-chlorophenoxy)ethyl]piperazine
CAS 662164-43-4C18H21ClN2O3S
1-(4-Methylphenyl)sulfonyl-4-[2-(4-propan-2-ylphenoxy)ethyl]piperazine chemical structure, C22H30N2O3S, CAS 593238-18-7
1-(4-Methylphenyl)sulfonyl-4-[2-(4-propan-2-ylphenoxy)ethyl]piperazine
CAS 593238-18-7C22H30N2O3S
1-(4-Bromophenyl)sulfonyl-4-[2-(2-chlorophenoxy)ethyl]piperazine chemical structure, C18H20BrClN2O3S, CAS 725706-46-7
1-(4-Bromophenyl)sulfonyl-4-[2-(2-chlorophenoxy)ethyl]piperazine
CAS 725706-46-7C18H20BrClN2O3S
1-(4-Fluorophenyl)sulfonyl-4-(2-phenoxyethyl)piperazine chemical structure, C18H21FN2O3S, CAS 878939-81-2
1-(4-Fluorophenyl)sulfonyl-4-(2-phenoxyethyl)piperazine
CAS 878939-81-2C18H21FN2O3S
1-[4-[4-(2-Phenoxyethyl)piperazin-1-yl]sulfonylphenyl]ethanone chemical structure, C20H24N2O4S, CAS 879152-98-4
1-[4-[4-(2-Phenoxyethyl)piperazin-1-yl]sulfonylphenyl]ethanone
CAS 879152-98-4C20H24N2O4S
1-(3-{[4-(2-Phenoxyethyl)piperazin-1-yl]sulfonyl}phenyl)ethan-1-one chemical structure, C20H24N2O4S, CAS 878931-30-7
1-(3-{[4-(2-Phenoxyethyl)piperazin-1-yl]sulfonyl}phenyl)ethan-1-one
CAS 878931-30-7C20H24N2O4S