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Murcko scaffold

N-(5-((2-Oxo-2-(phenylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide scaffold

577 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
577
With full pages
4
Scaffold SMILES

O=C(CSc1nnc(NC(=O)c2ccccc2)s1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(5-((2-Oxo-2-(phenylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide page
Murcko scaffold O=C(CSc1nnc(NC(=O)c2ccccc2)s1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 288 of 577 chemicals

2-Chloro-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C18H15ClN4O2S2, CAS 392292-11-4
2-Chloro-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392292-11-4C18H15ClN4O2S2
2-Bromo-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C18H15BrN4O2S2, CAS 392292-12-5
2-Bromo-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392292-12-5C18H15BrN4O2S2
3-Bromo-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C18H15BrN4O2S2, CAS 392292-13-6
3-Bromo-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392292-13-6C18H15BrN4O2S2
4-Bromo-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C18H15BrN4O2S2, CAS 392292-14-7
4-Bromo-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392292-14-7C18H15BrN4O2S2
2-Methoxy-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C19H18N4O3S2, CAS 392292-15-8
2-Methoxy-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392292-15-8C19H18N4O3S2
3-Methoxy-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C19H18N4O3S2, CAS 392292-16-9
3-Methoxy-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392292-16-9C19H18N4O3S2
4-Methoxy-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C19H18N4O3S2, CAS 392292-17-0
4-Methoxy-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392292-17-0C19H18N4O3S2
2-Fluoro-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C18H15FN4O2S2, CAS 392292-21-6
2-Fluoro-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392292-21-6C18H15FN4O2S2
3-Fluoro-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C18H15FN4O2S2, CAS 392292-22-7
3-Fluoro-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392292-22-7C18H15FN4O2S2
4-Fluoro-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C18H15FN4O2S2, CAS 392292-23-8
4-Fluoro-N-(5-((2-oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392292-23-8C18H15FN4O2S2
N-(5-((2-Oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)-3-(trifluoromethyl)benzamide chemical structure, C19H15F3N4O2S2, CAS 392292-24-9
N-(5-((2-Oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)-3-(trifluoromethyl)benzamide
CAS 392292-24-9C19H15F3N4O2S2
4-Fluoro-N-(5-((2-oxo-2-(phenylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C17H13FN4O2S2, CAS 392290-96-9
4-Fluoro-N-(5-((2-oxo-2-(phenylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392290-96-9C17H13FN4O2S2
N-[5-[2-(4-Fluoroanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]-3-methoxybenzamide chemical structure, C18H15FN4O3S2, CAS 392297-62-0
N-[5-[2-(4-Fluoroanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]-3-methoxybenzamide
CAS 392297-62-0C18H15FN4O3S2
3,5-Dichloro-N-(5-((2-((3,5-dimethylphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C19H16Cl2N4O2S2, CAS 392296-57-0
3,5-Dichloro-N-(5-((2-((3,5-dimethylphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392296-57-0C19H16Cl2N4O2S2
3,4-Dimethyl-N-(5-((2-oxo-2-(phenylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C19H18N4O2S2, CAS 392291-02-0
3,4-Dimethyl-N-(5-((2-oxo-2-(phenylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392291-02-0C19H18N4O2S2
N-[5-[2-(2,4-Dimethylanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]benzamide chemical structure, C19H18N4O2S2, CAS 392295-63-5
N-[5-[2-(2,4-Dimethylanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]benzamide
CAS 392295-63-5C19H18N4O2S2
2-Chloro-N-[5-[2-(4-fluoroanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]benzamide chemical structure, C17H12ClFN4O2S2, CAS 392297-57-3
2-Chloro-N-[5-[2-(4-fluoroanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]benzamide
CAS 392297-57-3C17H12ClFN4O2S2
5-Chloro-N-[5-[2-(4-ethoxyanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]-2-methoxybenzamide chemical structure, C20H19ClN4O4S2, CAS 391869-55-9
5-Chloro-N-[5-[2-(4-ethoxyanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]-2-methoxybenzamide
CAS 391869-55-9C20H19ClN4O4S2
2-Chloro-N-(5-((2-oxo-2-(p-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C18H15ClN4O2S2, CAS 392291-46-2
2-Chloro-N-(5-((2-oxo-2-(p-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392291-46-2C18H15ClN4O2S2
4-Butoxy-N-(5-((2-oxo-2-((2-(trifluoromethyl)phenyl)amino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C22H21F3N4O3S2, CAS 392297-14-2
4-Butoxy-N-(5-((2-oxo-2-((2-(trifluoromethyl)phenyl)amino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392297-14-2C22H21F3N4O3S2
N-(5-((2-((3,5-Dimethylphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-3-fluorobenzamide chemical structure, C19H17FN4O2S2, CAS 392296-41-2
N-(5-((2-((3,5-Dimethylphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-3-fluorobenzamide
CAS 392296-41-2C19H17FN4O2S2
3-Chloro-N-(5-((2-((4-methoxyphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C18H15ClN4O3S2, CAS 392293-68-4
3-Chloro-N-(5-((2-((4-methoxyphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392293-68-4C18H15ClN4O3S2
N-(5-((2-((3,5-Dimethylphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-2-methoxybenzamide chemical structure, C20H20N4O3S2, CAS 392296-34-3
N-(5-((2-((3,5-Dimethylphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-2-methoxybenzamide
CAS 392296-34-3C20H20N4O3S2
2,4-Dimethoxy-N-(5-((2-oxo-2-(p-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide chemical structure, C20H20N4O4S2, CAS 392291-75-7
2,4-Dimethoxy-N-(5-((2-oxo-2-(p-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
CAS 392291-75-7C20H20N4O4S2