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Murcko scaffold

4-Phenyl-1-(3-phenylpropyl)piperidine scaffold

42 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
42
With full pages
5
Scaffold SMILES

c1ccc(CCCN2CCC(c3ccccc3)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-1-(3-phenylpropyl)piperidine page
Murcko scaffold c1ccc(CCCN2CCC(c3ccccc3)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

Phenoperidine chemical structure, C23H29NO3, CAS 562-26-5
Phenoperidine
CAS 562-26-5C23H29NO3
4-Piperidinecarboxylic acid, 1-(3-hydroxy-3-phenylpropyl)-4-phenyl-, ethyl ester, hydrochloride (1:1) chemical structure, C23H30ClNO3, CAS 3627-49-4
4-Piperidinecarboxylic acid, 1-(3-hydroxy-3-phenylpropyl)-4-phenyl-, ethyl ester, hydrochloride (1:1)
CAS 3627-49-4C23H30ClNO3
2-Hydroxy-3-(4-iodophenyl)-1-(4-phenylpiperidinyl)propane chemical structure, C20H24INO, CAS 142472-57-9
2-Hydroxy-3-(4-iodophenyl)-1-(4-phenylpiperidinyl)propane
CAS 142472-57-9C20H24INO
LY 117413 chemical structure, C22H29NO2, CAS 82970-70-5
LY 117413
CAS 82970-70-5C22H29NO2
Alvimopan diastereomer 1 chemical structure, C25H32N2O4, CAS 342639-35-4
Alvimopan diastereomer 1
CAS 342639-35-4C25H32N2O4
4-Piperidinol, 4-phenyl-1-(3-phenylpropyl)-, propionate (ester), hydrochloride chemical structure, C23H30ClNO2, CAS 6849-01-0
4-Piperidinol, 4-phenyl-1-(3-phenylpropyl)-, propionate (ester), hydrochloride
CAS 6849-01-0C23H30ClNO2
2,5-Dimethyl-4-phenyl-1-(3-phenylpropyl)piperidin-4-yl propanoate--hydrogen chloride (1/1) chemical structure, C25H34ClNO2, CAS 64140-64-3
2,5-Dimethyl-4-phenyl-1-(3-phenylpropyl)piperidin-4-yl propanoate--hydrogen chloride (1/1)
CAS 64140-64-3C25H34ClNO2
4-Piperidinol, 2,3-dimethyl-4-phenyl-1-(3-phenylpropyl)- chemical structure, C22H29NO, CAS 76950-52-2
4-Piperidinol, 2,3-dimethyl-4-phenyl-1-(3-phenylpropyl)-
CAS 76950-52-2C22H29NO
Alvimopan dihydrate chemical structure, C25H36N2O6, CAS 170098-38-1
Alvimopan dihydrate
CAS 170098-38-1C25H36N2O6
Alvimopan chemical structure, C25H32N2O4, CAS 156053-89-3
Alvimopan
CAS 156053-89-3C25H32N2O4
2-(2-Benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic acid chemical structure, C25H32N2O4, CAS 342639-02-5
2-(2-Benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic acid
CAS 342639-02-5C25H32N2O4
(S)-Methyl 2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate hydrochloride chemical structure, C24H32ClNO3, CAS 170098-28-9
(S)-Methyl 2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate hydrochloride
CAS 170098-28-9C24H32ClNO3
(S)-Methyl 2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate chemical structure, C24H31NO3, CAS 170098-29-0
(S)-Methyl 2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate
CAS 170098-29-0C24H31NO3
Ethyl (S)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate hydrochloride chemical structure, C25H34ClNO3, CAS 170098-32-5
Ethyl (S)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate hydrochloride
CAS 170098-32-5C25H34ClNO3
Adl-08-0011 chemical structure, C23H29NO3, CAS 156130-41-5
Adl-08-0011
CAS 156130-41-5C23H29NO3
Ethyl 2-[[2-benzyl-3-[4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetate chemical structure, C27H36N2O4
Ethyl 2-[[2-benzyl-3-[4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetate
C27H36N2O4
Alvimopan impurity D chemical structure, C24H31NO3, CAS 170098-41-6
Alvimopan impurity D
CAS 170098-41-6C24H31NO3
4-[1-(3-Phenylpropyl)piperidin-4-yl]phenol chemical structure, C20H25NO, CAS 756805-80-8
4-[1-(3-Phenylpropyl)piperidin-4-yl]phenol
CAS 756805-80-8C20H25NO
4-(4-Chlorophenyl)-1-(3-phenylpropyl)piperidin-4-ol chemical structure, C20H24ClNO, CAS 193355-50-9
4-(4-Chlorophenyl)-1-(3-phenylpropyl)piperidin-4-ol
CAS 193355-50-9C20H24ClNO
Ethyl 4-phenyl-1-(3-phenylpropyl)piperidine-4-carboxylate chemical structure, C23H29NO2, CAS 102762-46-9
Ethyl 4-phenyl-1-(3-phenylpropyl)piperidine-4-carboxylate
CAS 102762-46-9C23H29NO2
3-[1-(2-Amino-3-phenylpropyl)-3,4-dimethyl-4-piperidinyl]phenol chemical structure, C22H30N2O, CAS 145340-58-5
3-[1-(2-Amino-3-phenylpropyl)-3,4-dimethyl-4-piperidinyl]phenol
CAS 145340-58-5C22H30N2O
1-(3-Hydroxy-3-phenylpropyl)-4-phenylpiperidin-4-yl propionate, hydrochloride chemical structure, C23H30ClNO3, CAS 16598-97-3
1-(3-Hydroxy-3-phenylpropyl)-4-phenylpiperidin-4-yl propionate, hydrochloride
CAS 16598-97-3C23H30ClNO3
1-Phenylpropyl-4-phenylpiperidine-4-carbonitrile chemical structure, C21H24N2, CAS 1041870-85-2
1-Phenylpropyl-4-phenylpiperidine-4-carbonitrile
CAS 1041870-85-2C21H24N2
Alvimopan-d5 chemical structure, C25H32N2O4, CAS 1217616-62-0
Alvimopan-d5
CAS 1217616-62-0C25H32N2O4