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Murcko scaffold

6-Oxaspiro[3.4]octan-2-one scaffold

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
14
With full pages
5
Scaffold SMILES

O=C1CC2(CCOC2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Oxaspiro[3.4]octan-2-one page
Murcko scaffold O=C1CC2(CCOC2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

6-Oxaspiro[3.4]octan-2-one chemical structure, C7H10O2, CAS 1638771-98-8
6-Oxaspiro[3.4]octan-2-one
CAS 1638771-98-8C7H10O2
7-(Hydroxymethyl)-6-oxaspiro(3.4)octan-2-one chemical structure, C8H12O3, CAS 2059971-87-6
7-(Hydroxymethyl)-6-oxaspiro(3.4)octan-2-one
CAS 2059971-87-6C8H12O3
7-(Iodomethyl)-6-oxaspiro[3.4]octan-2-one chemical structure, C8H11IO2, CAS 2060032-66-6
7-(Iodomethyl)-6-oxaspiro[3.4]octan-2-one
CAS 2060032-66-6C8H11IO2
7-(Bromomethyl)-6-oxaspiro[3.4]octan-2-one chemical structure, C8H11BrO2, CAS 2059971-74-1
7-(Bromomethyl)-6-oxaspiro[3.4]octan-2-one
CAS 2059971-74-1C8H11BrO2
7-Methyl-6-oxaspiro[3.4]octan-2-one chemical structure, C8H12O2, CAS 2126160-50-5
7-Methyl-6-oxaspiro[3.4]octan-2-one
CAS 2126160-50-5C8H12O2
7,7-Dimethyl-6-oxaspiro(3.4)octan-2-one chemical structure, C9H14O2, CAS 2126159-64-4
7,7-Dimethyl-6-oxaspiro(3.4)octan-2-one
CAS 2126159-64-4C9H14O2
7-(Aminomethyl)-6-oxaspiro[3.4]octan-2-one chemical structure, C8H13NO2, CAS 2060037-86-5
7-(Aminomethyl)-6-oxaspiro[3.4]octan-2-one
CAS 2060037-86-5C8H13NO2
tert-Butyl N-({2-oxo-6-oxaspiro[3.4]octan-7-yl}methyl)carbamate chemical structure, C13H21NO4, CAS 2287280-65-1
tert-Butyl N-({2-oxo-6-oxaspiro[3.4]octan-7-yl}methyl)carbamate
CAS 2287280-65-1C13H21NO4
{2-Oxo-6-oxaspiro[3.4]octan-7-yl}methanesulfonyl chloride chemical structure, C8H11ClO4S, CAS 2287312-80-3
{2-Oxo-6-oxaspiro[3.4]octan-7-yl}methanesulfonyl chloride
CAS 2287312-80-3C8H11ClO4S
7-(Aminomethyl)-6-oxaspiro[3.4]octan-2-one hydrochloride chemical structure, C8H14ClNO2, CAS 2551117-87-2
7-(Aminomethyl)-6-oxaspiro[3.4]octan-2-one hydrochloride
CAS 2551117-87-2C8H14ClNO2
7-(Azidomethyl)-6-oxaspiro[3.4]octan-2-one chemical structure, C8H11N3O2, CAS 2060041-78-1
7-(Azidomethyl)-6-oxaspiro[3.4]octan-2-one
CAS 2060041-78-1C8H11N3O2
2-{2-Oxo-6-oxaspiro[3.4]octan-7-yl}acetic acid chemical structure, C9H12O4, CAS 2137987-61-0
2-{2-Oxo-6-oxaspiro[3.4]octan-7-yl}acetic acid
CAS 2137987-61-0C9H12O4
{2-Oxo-6-oxaspiro[3.4]octan-7-yl}methanesulfonamide chemical structure, C8H13NO4S, CAS 2580185-84-6
{2-Oxo-6-oxaspiro[3.4]octan-7-yl}methanesulfonamide
CAS 2580185-84-6C8H13NO4S
{2-Oxo-6-oxaspiro[3.4]octan-7-yl}methanesulfonyl fluoride chemical structure, C8H11FO4S, CAS 2648956-35-6
{2-Oxo-6-oxaspiro[3.4]octan-7-yl}methanesulfonyl fluoride
CAS 2648956-35-6C8H11FO4S