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Murcko scaffold

Ring system with 3 rings and 19 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
13
With full pages
3
Scaffold SMILES

O=C(c1ccco1)N1CCN(c2ccccn2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccco1)N1CCN(c2ccccn2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

1-(5-Bromo-2-furoyl)-4-(2-pyridinyl)piperazine chemical structure, C14H14BrN3O2, CAS 667879-18-7
1-(5-Bromo-2-furoyl)-4-(2-pyridinyl)piperazine
CAS 667879-18-7C14H14BrN3O2
Furan-2-yl-[4-(5-nitropyridin-2-yl)piperazin-1-yl]methanone chemical structure, C14H14N4O4, CAS 419542-63-5
Furan-2-yl-[4-(5-nitropyridin-2-yl)piperazin-1-yl]methanone
CAS 419542-63-5C14H14N4O4
(5-Methylfuran-2-yl)-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone chemical structure, C16H16F3N3O2, CAS 796057-31-3
(5-Methylfuran-2-yl)-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
CAS 796057-31-3C16H16F3N3O2
2-[4-(Furan-2-carbonyl)piperazin-1-yl]-4,6-dimethylpyridine-3-carbonitrile chemical structure, C17H18N4O2, CAS 949319-76-0
2-[4-(Furan-2-carbonyl)piperazin-1-yl]-4,6-dimethylpyridine-3-carbonitrile
CAS 949319-76-0C17H18N4O2
6-[4-(Furan-2-carbonyl)piperazin-1-yl]pyridin-3-amine chemical structure, C14H16N4O2, CAS 1017171-70-8
6-[4-(Furan-2-carbonyl)piperazin-1-yl]pyridin-3-amine
CAS 1017171-70-8C14H16N4O2
1-(3-Chloropyridin-2-yl)-4-(furan-2-carbonyl)piperazine chemical structure, C14H14ClN3O2, CAS 2180858-70-0
1-(3-Chloropyridin-2-yl)-4-(furan-2-carbonyl)piperazine
CAS 2180858-70-0C14H14ClN3O2
1-(Furan-2-carbonyl)-4-(6-methylpyridin-2-yl)piperazine chemical structure, C15H17N3O2, CAS 2097893-62-2
1-(Furan-2-carbonyl)-4-(6-methylpyridin-2-yl)piperazine
CAS 2097893-62-2C15H17N3O2
5-Chloro-2-[4-(furan-2-carbonyl)piperazin-1-yl]-4,6-dimethylpyridine-3-carbonitrile chemical structure, C17H17ClN4O2, CAS 2742037-97-2
5-Chloro-2-[4-(furan-2-carbonyl)piperazin-1-yl]-4,6-dimethylpyridine-3-carbonitrile
CAS 2742037-97-2C17H17ClN4O2
1-(3-Bromopyridin-2-yl)-4-(furan-2-carbonyl)piperazine chemical structure, C14H14BrN3O2, CAS 2877669-60-6
1-(3-Bromopyridin-2-yl)-4-(furan-2-carbonyl)piperazine
CAS 2877669-60-6C14H14BrN3O2
5-Bromo-2-[4-(furan-2-carbonyl)piperazin-1-yl]pyridine-3-carbonitrile chemical structure, C15H13BrN4O2, CAS 2877704-59-9
5-Bromo-2-[4-(furan-2-carbonyl)piperazin-1-yl]pyridine-3-carbonitrile
CAS 2877704-59-9C15H13BrN4O2
1-(Furan-2-carbonyl)-4-(4-methylpyridin-2-yl)piperazine chemical structure, C15H17N3O2, CAS 3054436-45-9
1-(Furan-2-carbonyl)-4-(4-methylpyridin-2-yl)piperazine
CAS 3054436-45-9C15H17N3O2
1-(6-Fluoropyridin-2-yl)-2-methyl-4-{5-[(propan-2-yloxy)methyl]furan-2-carbonyl}piperazine chemical structure, C19H24FN3O3, CAS 3054562-51-2
1-(6-Fluoropyridin-2-yl)-2-methyl-4-{5-[(propan-2-yloxy)methyl]furan-2-carbonyl}piperazine
CAS 3054562-51-2C19H24FN3O3
(4-(4-Chloropyridin-2-yl)piperazin-1-yl)(furan-2-yl)methanone chemical structure, C14H14ClN3O2, CAS 2402555-06-8
(4-(4-Chloropyridin-2-yl)piperazin-1-yl)(furan-2-yl)methanone
CAS 2402555-06-8C14H14ClN3O2