CompoundList
Murcko scaffold

2-Oxa-5-azaspiro(3.4)octane scaffold

38 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
38
With full pages
6
Scaffold SMILES

C1CNC2(C1)COC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Murcko scaffold C1CNC2(C1)COC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 38 of 38 chemicals

tert-Butyl 2-oxa-5-azaspiro[3.4]octane-5-carboxylate chemical structure, C11H19NO3, CAS 1245816-30-1
tert-Butyl 2-oxa-5-azaspiro[3.4]octane-5-carboxylate
CAS 1245816-30-1C11H19NO3
2-Oxa-5-azaspiro(3.4)octane chemical structure, C6H11NO, CAS 90207-55-9
2-Oxa-5-azaspiro(3.4)octane
CAS 90207-55-9C6H11NO
2-Oxa-5-azaspiro(3.4)octane, hemioxalate salt chemical structure, C14H24N2O6, CAS 1380571-82-3
2-Oxa-5-azaspiro(3.4)octane, hemioxalate salt
CAS 1380571-82-3C14H24N2O6
2-Oxa-5-azaspiro(3.4)octane oxalate chemical structure, C8H13NO5, CAS 1389264-18-9
2-Oxa-5-azaspiro(3.4)octane oxalate
CAS 1389264-18-9C8H13NO5
6-Methyl-2-oxa-5-azaspiro[3.4]octane chemical structure, C7H13NO, CAS 1499012-95-1
6-Methyl-2-oxa-5-azaspiro[3.4]octane
CAS 1499012-95-1C7H13NO
Ethyl 2-oxa-5-azaspiro[3.4]octane-7-carboxylate chemical structure, C9H15NO3, CAS 1538626-86-6
Ethyl 2-oxa-5-azaspiro[3.4]octane-7-carboxylate
CAS 1538626-86-6C9H15NO3
tert-Butyl 7-amino-2-oxa-5-azaspiro[3.4]octane-5-carboxylate chemical structure, C11H20N2O3, CAS 1538626-90-2
tert-Butyl 7-amino-2-oxa-5-azaspiro[3.4]octane-5-carboxylate
CAS 1538626-90-2C11H20N2O3
5-((tert-Butoxy)carbonyl)-2-oxa-5-azaspiro(3.4)octane-7-carboxylic acid chemical structure, C12H19NO5, CAS 1538626-88-8
5-((tert-Butoxy)carbonyl)-2-oxa-5-azaspiro(3.4)octane-7-carboxylic acid
CAS 1538626-88-8C12H19NO5
2-Oxa-5-azaspiro[3.4]octane, trifluoroacetic acid chemical structure, C8H12F3NO3, CAS 1419590-65-0
2-Oxa-5-azaspiro[3.4]octane, trifluoroacetic acid
CAS 1419590-65-0C8H12F3NO3
5-((tert-Butoxy)carbonyl)-2-oxa-5-azaspiro(3.4)octane-8-carboxylic acid chemical structure, C12H19NO5, CAS 2248384-55-4
5-((tert-Butoxy)carbonyl)-2-oxa-5-azaspiro(3.4)octane-8-carboxylic acid
CAS 2248384-55-4C12H19NO5
Ethyl 2-oxa-5-azaspiro[3.4]octane-8-carboxylate chemical structure, C9H15NO3, CAS 2028342-09-6
Ethyl 2-oxa-5-azaspiro[3.4]octane-8-carboxylate
CAS 2028342-09-6C9H15NO3
tert-Butyl 7-(hydroxymethyl)-7-methyl-2-oxa-5-azaspiro[3.4]octane-5-carboxylate chemical structure, C13H23NO4, CAS 2607831-12-7
tert-Butyl 7-(hydroxymethyl)-7-methyl-2-oxa-5-azaspiro[3.4]octane-5-carboxylate
CAS 2607831-12-7C13H23NO4
tert-Butyl 7-ethynyl-7-methyl-2-oxa-5-azaspiro[3.4]octane-5-carboxylate chemical structure, C14H21NO3, CAS 2607831-16-1
tert-Butyl 7-ethynyl-7-methyl-2-oxa-5-azaspiro[3.4]octane-5-carboxylate
CAS 2607831-16-1C14H21NO3
tert-Butyl (S)-7-hydroxy-2-oxa-5-azaspiro[3.4]octane-5-carboxylate chemical structure, C11H19NO4, CAS 2989668-51-9
tert-Butyl (S)-7-hydroxy-2-oxa-5-azaspiro[3.4]octane-5-carboxylate
CAS 2989668-51-9C11H19NO4
Methyl 7-methyl-2-oxa-5-azaspiro[3.4]octane-7-carboxylate chemical structure, C9H15NO3, CAS 2838329-20-5
Methyl 7-methyl-2-oxa-5-azaspiro[3.4]octane-7-carboxylate
CAS 2838329-20-5C9H15NO3
5-(tert-Butoxycarbonyl)-7-methyl-2-oxa-5-azaspiro[3.4]octane-7-carboxylic acid chemical structure, C13H21NO5, CAS 2841419-55-2
5-(tert-Butoxycarbonyl)-7-methyl-2-oxa-5-azaspiro[3.4]octane-7-carboxylic acid
CAS 2841419-55-2C13H21NO5
2-Oxa-5-azaspiro[3.4]octane hydrochloride chemical structure, C6H12ClNO, CAS 2803460-92-4
2-Oxa-5-azaspiro[3.4]octane hydrochloride
CAS 2803460-92-4C6H12ClNO
5-(tert-Butylsulfonyl)-2-oxa-5-azaspiro[3.4]octan-7-ol chemical structure, C10H19NO4S, CAS 2817639-10-2
5-(tert-Butylsulfonyl)-2-oxa-5-azaspiro[3.4]octan-7-ol
CAS 2817639-10-2C10H19NO4S
5-Methyl-2-oxa-5-azaspiro[3.4]octan-8-amine chemical structure, C7H14N2O, CAS 2137457-90-8
5-Methyl-2-oxa-5-azaspiro[3.4]octan-8-amine
CAS 2137457-90-8C7H14N2O
5-Ethyl-2-oxa-5-azaspiro[3.4]octan-8-amine chemical structure, C8H16N2O, CAS 2137462-68-9
5-Ethyl-2-oxa-5-azaspiro[3.4]octan-8-amine
CAS 2137462-68-9C8H16N2O
5-(Propan-2-yl)-2-oxa-5-azaspiro[3.4]octan-8-amine chemical structure, C9H18N2O, CAS 2137484-20-7
5-(Propan-2-yl)-2-oxa-5-azaspiro[3.4]octan-8-amine
CAS 2137484-20-7C9H18N2O
tert-Butyl 2-oxa-5-azaspiro[3.4]octane-8-carboxylate chemical structure, C11H19NO3, CAS 2580243-70-3
tert-Butyl 2-oxa-5-azaspiro[3.4]octane-8-carboxylate
CAS 2580243-70-3C11H19NO3
2-Oxa-5-azaspiro[3.4]octane-8-carboxylic acid chemical structure, C7H11NO3, CAS 2387064-39-1
2-Oxa-5-azaspiro[3.4]octane-8-carboxylic acid
CAS 2387064-39-1C7H11NO3
Methyl 2-oxa-5-azaspiro[3.4]octane-8-carboxylate chemical structure, C8H13NO3, CAS 2580223-89-6
Methyl 2-oxa-5-azaspiro[3.4]octane-8-carboxylate
CAS 2580223-89-6C8H13NO3