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Murcko scaffold

N-Phenyl-4-(2-pyridinyl)-2-thiazolamine scaffold

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
20
With full pages
5
Scaffold SMILES

c1ccc(Nc2nc(-c3ccccn3)cs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-4-(2-pyridinyl)-2-thiazolamine page
Murcko scaffold c1ccc(Nc2nc(-c3ccccn3)cs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

3-[(4-Pyridin-2-yl-1,3-thiazol-2-yl)amino]phenol chemical structure, C14H11N3OS, CAS 315702-75-1
3-[(4-Pyridin-2-yl-1,3-thiazol-2-yl)amino]phenol
CAS 315702-75-1C14H11N3OS
4-[(4-Pyridin-2-yl-1,3-thiazol-2-yl)amino]phenol chemical structure, C14H11N3OS, CAS 315702-79-5
4-[(4-Pyridin-2-yl-1,3-thiazol-2-yl)amino]phenol
CAS 315702-79-5C14H11N3OS
3-(4-Pyridin-2-yl-thiazol-2-ylamino)-benzoic acid chemical structure, C15H11N3O2S, CAS 315702-87-5
3-(4-Pyridin-2-yl-thiazol-2-ylamino)-benzoic acid
CAS 315702-87-5C15H11N3O2S
Benzoic acid, 4-[[4-(2-pyridinyl)-2-thiazolyl]amino]- chemical structure, C15H11N3O2S, CAS 315702-88-6
Benzoic acid, 4-[[4-(2-pyridinyl)-2-thiazolyl]amino]-
CAS 315702-88-6C15H11N3O2S
4-N,4-N-diethyl-1-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)benzene-1,4-diamine chemical structure, C18H20N4S, CAS 315702-91-1
4-N,4-N-diethyl-1-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)benzene-1,4-diamine
CAS 315702-91-1C18H20N4S
4-[(4-Pyridin-2-yl-1,3-thiazol-2-yl)amino]benzenesulfonamide chemical structure, C14H12N4O2S2, CAS 5750-00-5
4-[(4-Pyridin-2-yl-1,3-thiazol-2-yl)amino]benzenesulfonamide
CAS 5750-00-5C14H12N4O2S2
C.I. Direct Violet 3 chemical structure, C16H15N3S, CAS 6507-83-1
C.I. Direct Violet 3
CAS 6507-83-1C16H15N3S
N-(4-Pyridin-2-yl-thiazol-2-yl)benzene-1,4-diamine chemical structure, C14H12N4S, CAS 315702-89-7
N-(4-Pyridin-2-yl-thiazol-2-yl)benzene-1,4-diamine
CAS 315702-89-7C14H12N4S
N-Phenyl-4-(2-pyridinyl)-2-thiazolamine chemical structure, C14H11N3S, CAS 315702-76-2
N-Phenyl-4-(2-pyridinyl)-2-thiazolamine
CAS 315702-76-2C14H11N3S
N-(3,4-Dimethylphenyl)-4-(pyridin-2-yl)-1,3-thiazol-2-amine chemical structure, C16H15N3S, CAS 708287-41-6
N-(3,4-Dimethylphenyl)-4-(pyridin-2-yl)-1,3-thiazol-2-amine
CAS 708287-41-6C16H15N3S
N-(2,4-Dimethoxyphenyl)-4-(pyridin-2-yl)-1,3-thiazol-2-amine chemical structure, C16H15N3O2S, CAS 708994-57-4
N-(2,4-Dimethoxyphenyl)-4-(pyridin-2-yl)-1,3-thiazol-2-amine
CAS 708994-57-4C16H15N3O2S
1-[4-[(4-Pyridin-2-yl-1,3-thiazol-2-yl)amino]phenyl]ethanone chemical structure, C16H13N3OS, CAS 797776-17-1
1-[4-[(4-Pyridin-2-yl-1,3-thiazol-2-yl)amino]phenyl]ethanone
CAS 797776-17-1C16H13N3OS
4-(2-Pyridyl)-N-[4-(trifluoromethyl)phenyl]thiazol-2-amine chemical structure, C15H10F3N3S, CAS 758689-08-6
4-(2-Pyridyl)-N-[4-(trifluoromethyl)phenyl]thiazol-2-amine
CAS 758689-08-6C15H10F3N3S
N-(4-Pyridin-2-YL-thiazol-2-yl)-benzene-1,4-diamine hydrobromide chemical structure, C14H13BrN4S, CAS 1185302-23-1
N-(4-Pyridin-2-YL-thiazol-2-yl)-benzene-1,4-diamine hydrobromide
CAS 1185302-23-1C14H13BrN4S
N1-[4-(2-Pyridinyl)-2-thiazolyl]-1,3-benzenediamine chemical structure, C14H12N4S, CAS 1215995-08-6
N1-[4-(2-Pyridinyl)-2-thiazolyl]-1,3-benzenediamine
CAS 1215995-08-6C14H12N4S
4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-phenyl-1,3-thiazol-2-amine chemical structure, C15H9ClF3N3S, CAS 2060748-37-8
4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-phenyl-1,3-thiazol-2-amine
CAS 2060748-37-8C15H9ClF3N3S
4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-chlorophenyl)-1,3-thiazol-2-amine chemical structure, C15H8Cl2F3N3S, CAS 2058813-24-2
4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-chlorophenyl)-1,3-thiazol-2-amine
CAS 2058813-24-2C15H8Cl2F3N3S
4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(2-chlorophenyl)-1,3-thiazol-2-amine chemical structure, C15H8Cl2F3N3S, CAS 2061249-19-0
4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(2-chlorophenyl)-1,3-thiazol-2-amine
CAS 2061249-19-0C15H8Cl2F3N3S
4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine chemical structure, C16H8ClF6N3S, CAS 2061726-61-0
4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-amine
CAS 2061726-61-0C16H8ClF6N3S
2-(2-((3-Fluorophenyl)amino)thiazol-4-yl)isonicotinic acid chemical structure, C15H10FN3O2S, CAS 1797019-23-8
2-(2-((3-Fluorophenyl)amino)thiazol-4-yl)isonicotinic acid
CAS 1797019-23-8C15H10FN3O2S