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Murcko scaffold

Ring system with 3 rings and 21 atoms

257 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
257
With full pages
35
Scaffold SMILES

O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 257 of 257 chemicals

N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-4-propoxybenzamide chemical structure, C25H33N3O3, CAS 895074-38-1
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-4-propoxybenzamide
CAS 895074-38-1C25H33N3O3
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-3,4-dimethylbenzamide chemical structure, C24H31N3O2, CAS 895077-25-5
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-3,4-dimethylbenzamide
CAS 895077-25-5C24H31N3O2
4-Methyl-N-[4-[4-(3-methylbutanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C23H29N3O2, CAS 895080-33-8
4-Methyl-N-[4-[4-(3-methylbutanoyl)piperazin-1-yl]phenyl]benzamide
CAS 895080-33-8C23H29N3O2
3-Methyl-N-[4-[4-(3-methylbutanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C23H29N3O2, CAS 895083-01-9
3-Methyl-N-[4-[4-(3-methylbutanoyl)piperazin-1-yl]phenyl]benzamide
CAS 895083-01-9C23H29N3O2
3-Fluoro-N-[4-[4-(3-methylbutanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C22H26FN3O2, CAS 895084-36-3
3-Fluoro-N-[4-[4-(3-methylbutanoyl)piperazin-1-yl]phenyl]benzamide
CAS 895084-36-3C22H26FN3O2
N-[3-Chloro-4-[4-(2,2-dimethylpropanoyl)piperazin-1-yl]phenyl]-4-methoxybenzamide chemical structure, C23H28ClN3O3, CAS 898114-08-4
N-[3-Chloro-4-[4-(2,2-dimethylpropanoyl)piperazin-1-yl]phenyl]-4-methoxybenzamide
CAS 898114-08-4C23H28ClN3O3
N-[3-Chloro-4-[4-(2,2-dimethylpropanoyl)piperazin-1-yl]phenyl]-2-methylbenzamide chemical structure, C23H28ClN3O2, CAS 898116-25-1
N-[3-Chloro-4-[4-(2,2-dimethylpropanoyl)piperazin-1-yl]phenyl]-2-methylbenzamide
CAS 898116-25-1C23H28ClN3O2
N-[3-Chloro-4-[4-(2,2-dimethylpropanoyl)piperazin-1-yl]phenyl]-3-fluorobenzamide chemical structure, C22H25ClFN3O2, CAS 898117-77-6
N-[3-Chloro-4-[4-(2,2-dimethylpropanoyl)piperazin-1-yl]phenyl]-3-fluorobenzamide
CAS 898117-77-6C22H25ClFN3O2
4-Iodo-N-[3-nitro-4-(piperazin-1-yl)phenyl]benzamide chemical structure, C17H17IN4O3, CAS 1071416-26-6
4-Iodo-N-[3-nitro-4-(piperazin-1-yl)phenyl]benzamide
CAS 1071416-26-6C17H17IN4O3
2-Amino-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H22N4O, CAS 1018500-15-6
2-Amino-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 1018500-15-6C18H22N4O
4-Ethyl-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide chemical structure, C22H27N3O2, CAS 1158565-82-2
4-Ethyl-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide
CAS 1158565-82-2C22H27N3O2
N-[4-(4-Methylpiperazin-1-yl)phenyl]-2-(methylsulfanyl)benzamide chemical structure, C19H23N3OS, CAS 1242831-14-6
N-[4-(4-Methylpiperazin-1-yl)phenyl]-2-(methylsulfanyl)benzamide
CAS 1242831-14-6C19H23N3OS
4-Methoxy-N-[4-(4-methylpiperazin-1-yl)phenyl]-3-(prop-2-en-1-yl)benzamide chemical structure, C22H27N3O2, CAS 1242841-81-1
4-Methoxy-N-[4-(4-methylpiperazin-1-yl)phenyl]-3-(prop-2-en-1-yl)benzamide
CAS 1242841-81-1C22H27N3O2
N-[4-(4-Methylpiperazin-1-yl)phenyl]-2-(propan-2-yloxy)benzamide chemical structure, C21H27N3O2, CAS 1269280-48-9
N-[4-(4-Methylpiperazin-1-yl)phenyl]-2-(propan-2-yloxy)benzamide
CAS 1269280-48-9C21H27N3O2
N-[3-Amino-4-(4-methylpiperazin-1-yl)phenyl]-4-isopropylbenzamide chemical structure, C21H28N4O, CAS 1779121-63-9
N-[3-Amino-4-(4-methylpiperazin-1-yl)phenyl]-4-isopropylbenzamide
CAS 1779121-63-9C21H28N4O
tert-Butyl 4-[4-[(4-hydroxy-2-methylbenzoyl)amino]phenyl]piperazine-1-carboxylate chemical structure, C23H29N3O4, CAS 1435934-07-8
tert-Butyl 4-[4-[(4-hydroxy-2-methylbenzoyl)amino]phenyl]piperazine-1-carboxylate
CAS 1435934-07-8C23H29N3O4
4-Chloro-N-[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]benzamide hydrochloride chemical structure, C18H20Cl2FN3O, CAS 477762-23-5
4-Chloro-N-[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]benzamide hydrochloride
CAS 477762-23-5C18H20Cl2FN3O