CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 21 atoms

257 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
257
With full pages
35
Scaffold SMILES

O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 257 chemicals

4-Ethoxy-N-[4-(4-ethylpiperazin-1-yl)phenyl]benzamide chemical structure, C21H27N3O2, CAS 792939-89-0
4-Ethoxy-N-[4-(4-ethylpiperazin-1-yl)phenyl]benzamide
CAS 792939-89-0C21H27N3O2
4-Methyl-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C22H27N3O2, CAS 674353-58-3
4-Methyl-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 674353-58-3C22H27N3O2
2-Methoxy-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C22H27N3O3, CAS 673495-88-0
2-Methoxy-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 673495-88-0C22H27N3O3
3,4,5-Trimethoxy-N-{4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl}benzamide chemical structure, C24H31N3O5, CAS 674330-86-0
3,4,5-Trimethoxy-N-{4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl}benzamide
CAS 674330-86-0C24H31N3O5
2-Fluoro-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C21H24FN3O2, CAS 673494-32-1
2-Fluoro-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 673494-32-1C21H24FN3O2
3-Fluoro-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C21H24FN3O2, CAS 676155-67-2
3-Fluoro-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 676155-67-2C21H24FN3O2
4-Fluoro-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C21H24FN3O2, CAS 673444-43-4
4-Fluoro-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 673444-43-4C21H24FN3O2
N-[4-(4-Methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H21N3O3S, CAS 672342-91-5
N-[4-(4-Methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 672342-91-5C18H21N3O3S
4-Methyl-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H23N3O3S, CAS 673494-96-7
4-Methyl-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 673494-96-7C19H23N3O3S
3-Methoxy-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H23N3O4S, CAS 674360-40-8
3-Methoxy-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 674360-40-8C19H23N3O4S
2-Fluoro-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H20FN3O3S, CAS 674356-87-7
2-Fluoro-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 674356-87-7C18H20FN3O3S
2-Chloro-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H20ClN3O3S, CAS 672338-29-3
2-Chloro-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 672338-29-3C18H20ClN3O3S
3-Fluoro-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H20FN3O3S, CAS 674338-15-9
3-Fluoro-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 674338-15-9C18H20FN3O3S
4-Fluoro-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H20FN3O3S, CAS 674338-04-6
4-Fluoro-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 674338-04-6C18H20FN3O3S
4-Chloro-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H20ClN3O3S, CAS 674352-53-5
4-Chloro-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 674352-53-5C18H20ClN3O3S
2,4-Dichloro-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C18H19Cl2N3O3S, CAS 674353-37-8
2,4-Dichloro-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 674353-37-8C18H19Cl2N3O3S
N-[3-Chloro-4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]-2,4-dimethylbenzamide chemical structure, C23H28ClN3O2, CAS 672920-68-2
N-[3-Chloro-4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]-2,4-dimethylbenzamide
CAS 672920-68-2C23H28ClN3O2
N-[3-Chloro-4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]-2,6-dimethoxybenzamide chemical structure, C23H28ClN3O4, CAS 671818-58-9
N-[3-Chloro-4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]-2,6-dimethoxybenzamide
CAS 671818-58-9C23H28ClN3O4
2,6-Dimethoxy-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide chemical structure, C22H27N3O4, CAS 701231-56-3
2,6-Dimethoxy-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide
CAS 701231-56-3C22H27N3O4
N-[4-(4-Butanoylpiperazin-1-yl)phenyl]-2-fluorobenzamide chemical structure, C21H24FN3O2, CAS 688028-64-0
N-[4-(4-Butanoylpiperazin-1-yl)phenyl]-2-fluorobenzamide
CAS 688028-64-0C21H24FN3O2
3-Methyl-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H23N3O3S, CAS 674358-11-3
3-Methyl-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 674358-11-3C19H23N3O3S
N-[4-(4-Propanoylpiperazin-1-yl)phenyl]benzamide chemical structure, C20H23N3O2, CAS 688034-16-4
N-[4-(4-Propanoylpiperazin-1-yl)phenyl]benzamide
CAS 688034-16-4C20H23N3O2
N-[4-(4-Ethylpiperazin-1-yl)phenyl]-2-methoxy-3-methylbenzamide chemical structure, C21H27N3O2, CAS 792939-95-8
N-[4-(4-Ethylpiperazin-1-yl)phenyl]-2-methoxy-3-methylbenzamide
CAS 792939-95-8C21H27N3O2
2-Methyl-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H23N3O3S, CAS 672934-69-9
2-Methyl-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 672934-69-9C19H23N3O3S