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Murcko scaffold

Ring system with 3 rings and 21 atoms

257 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
257
With full pages
35
Scaffold SMILES

O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 240 of 257 chemicals

N-[3-Chloro-4-(4-methylpiperazin-1-yl)phenyl]-2,4-dimethoxybenzamide chemical structure, C20H24ClN3O3, CAS 878436-75-0
N-[3-Chloro-4-(4-methylpiperazin-1-yl)phenyl]-2,4-dimethoxybenzamide
CAS 878436-75-0C20H24ClN3O3
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-2-fluorobenzamide chemical structure, C22H26FN3O2, CAS 878416-31-0
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-2-fluorobenzamide
CAS 878416-31-0C22H26FN3O2
3-Butoxy-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide chemical structure, C24H31N3O3, CAS 688034-40-4
3-Butoxy-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide
CAS 688034-40-4C24H31N3O3
3,4-Dichloro-N-{3-fluoro-4-[4-(methylsulfonyl)piperazino]phenyl}benzenecarboxamide chemical structure, C18H18Cl2FN3O3S, CAS 478260-26-3
3,4-Dichloro-N-{3-fluoro-4-[4-(methylsulfonyl)piperazino]phenyl}benzenecarboxamide
CAS 478260-26-3C18H18Cl2FN3O3S
N-[4-(4-Butanoylpiperazin-1-yl)phenyl]-3-fluorobenzamide chemical structure, C21H24FN3O2, CAS 688029-00-7
N-[4-(4-Butanoylpiperazin-1-yl)phenyl]-3-fluorobenzamide
CAS 688029-00-7C21H24FN3O2
N-[4-(4-Butanoylpiperazin-1-yl)phenyl]-3-chlorobenzamide chemical structure, C21H24ClN3O2, CAS 688331-26-2
N-[4-(4-Butanoylpiperazin-1-yl)phenyl]-3-chlorobenzamide
CAS 688331-26-2C21H24ClN3O2
3-Chloro-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C21H24ClN3O2, CAS 672914-11-3
3-Chloro-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 672914-11-3C21H24ClN3O2
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-2-bromobenzamide chemical structure, C19H20BrN3O2, CAS 353760-76-6
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-2-bromobenzamide
CAS 353760-76-6C19H20BrN3O2
N-{3-Fluoro-4-[4-(methylsulfonyl)piperazino]phenyl}-4-methylbenzenecarboxamide chemical structure, C19H22FN3O3S, CAS 478260-25-2
N-{3-Fluoro-4-[4-(methylsulfonyl)piperazino]phenyl}-4-methylbenzenecarboxamide
CAS 478260-25-2C19H22FN3O3S
N-[2-Amino-4-(4-methylpiperazino)phenyl]-3-chlorobenzenecarboxamide chemical structure, C18H21ClN4O, CAS 439107-46-7
N-[2-Amino-4-(4-methylpiperazino)phenyl]-3-chlorobenzenecarboxamide
CAS 439107-46-7C18H21ClN4O
4-tert-Butyl-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C22H29N3O, CAS 640241-52-7
4-tert-Butyl-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 640241-52-7C22H29N3O
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-3,5-dichloro-2-methoxybenzamide chemical structure, C20H21Cl2N3O3, CAS 876885-60-8
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-3,5-dichloro-2-methoxybenzamide
CAS 876885-60-8C20H21Cl2N3O3
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-2,4-dimethoxybenzamide chemical structure, C21H25N3O4, CAS 897546-98-4
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-2,4-dimethoxybenzamide
CAS 897546-98-4C21H25N3O4
N-[4-(4-Propanoylpiperazin-1-yl)phenyl]-4-propan-2-ylbenzamide chemical structure, C23H29N3O2, CAS 898110-33-3
N-[4-(4-Propanoylpiperazin-1-yl)phenyl]-4-propan-2-ylbenzamide
CAS 898110-33-3C23H29N3O2
N-[4-(4-Methylpiperazin-1-yl)phenyl]-4-(2-methylpropoxy)benzamide chemical structure, C22H29N3O2, CAS 898655-21-5
N-[4-(4-Methylpiperazin-1-yl)phenyl]-4-(2-methylpropoxy)benzamide
CAS 898655-21-5C22H29N3O2
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-3-fluorobenzamide chemical structure, C22H26FN3O2, CAS 895078-96-3
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-3-fluorobenzamide
CAS 895078-96-3C22H26FN3O2
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-3-methylbenzamide chemical structure, C23H29N3O2, CAS 895077-18-6
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-3-methylbenzamide
CAS 895077-18-6C23H29N3O2
4-Cyano-N-[4-[4-(2,2-dimethylpropanoyl)piperazin-1-yl]phenyl]-2-fluorobenzamide chemical structure, C23H25FN4O2, CAS 895081-18-2
4-Cyano-N-[4-[4-(2,2-dimethylpropanoyl)piperazin-1-yl]phenyl]-2-fluorobenzamide
CAS 895081-18-2C23H25FN4O2
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-2-methylbenzamide chemical structure, C23H29N3O2, CAS 895077-10-8
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-2-methylbenzamide
CAS 895077-10-8C23H29N3O2
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-4-fluorobenzamide chemical structure, C22H26FN3O2, CAS 895076-05-8
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-4-fluorobenzamide
CAS 895076-05-8C22H26FN3O2
N-[4-[4-(3-Methylbutanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C22H27N3O2, CAS 895081-58-0
N-[4-[4-(3-Methylbutanoyl)piperazin-1-yl]phenyl]benzamide
CAS 895081-58-0C22H27N3O2
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-2-methoxybenzamide chemical structure, C23H29N3O3, CAS 895074-00-7
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-2-methoxybenzamide
CAS 895074-00-7C23H29N3O3
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-3,4-dimethoxybenzamide chemical structure, C24H31N3O4, CAS 895078-36-1
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-3,4-dimethoxybenzamide
CAS 895078-36-1C24H31N3O4
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-4-methylbenzamide chemical structure, C23H29N3O2, CAS 895073-92-4
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-4-methylbenzamide
CAS 895073-92-4C23H29N3O2