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Murcko scaffold

Ring system with 3 rings and 21 atoms

257 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
257
With full pages
35
Scaffold SMILES

O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 257 chemicals

N-[4-(4-Butanoylpiperazin-1-yl)phenyl]-3,5-dichloro-4-methoxybenzamide chemical structure, C22H25Cl2N3O3, CAS 832108-16-4
N-[4-(4-Butanoylpiperazin-1-yl)phenyl]-3,5-dichloro-4-methoxybenzamide
CAS 832108-16-4C22H25Cl2N3O3
3-Bromo-4-methoxy-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide chemical structure, C21H24BrN3O3, CAS 832123-09-8
3-Bromo-4-methoxy-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide
CAS 832123-09-8C21H24BrN3O3
5-Chloro-N-[3-chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-2-methoxybenzamide chemical structure, C21H23Cl2N3O3, CAS 833430-60-7
5-Chloro-N-[3-chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-2-methoxybenzamide
CAS 833430-60-7C21H23Cl2N3O3
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-3,5-dimethoxybenzamide chemical structure, C22H26ClN3O4, CAS 833434-47-2
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-3,5-dimethoxybenzamide
CAS 833434-47-2C22H26ClN3O4
2,3,5,6-Tetrafluoro-4-methoxy-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide chemical structure, C21H21F4N3O3, CAS 833439-99-9
2,3,5,6-Tetrafluoro-4-methoxy-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide
CAS 833439-99-9C21H21F4N3O3
N-[3-Chloro-4-(4-methylpiperazin-1-yl)phenyl]-3,4,5-trimethoxybenzamide chemical structure, C21H26ClN3O4, CAS 835899-57-5
N-[3-Chloro-4-(4-methylpiperazin-1-yl)phenyl]-3,4,5-trimethoxybenzamide
CAS 835899-57-5C21H26ClN3O4
4-(2-Methylpropoxy)-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide chemical structure, C22H29N3O4S, CAS 892165-74-1
4-(2-Methylpropoxy)-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]benzamide
CAS 892165-74-1C22H29N3O4S
3,4-Dimethoxy-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide chemical structure, C23H29N3O4, CAS 838818-46-5
3,4-Dimethoxy-N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]benzamide
CAS 838818-46-5C23H29N3O4
3-(2-Methylpropoxy)-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide chemical structure, C24H31N3O3, CAS 838895-23-1
3-(2-Methylpropoxy)-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide
CAS 838895-23-1C24H31N3O3
3,4-Dimethyl-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide chemical structure, C22H27N3O2, CAS 839682-11-0
3,4-Dimethyl-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide
CAS 839682-11-0C22H27N3O2
3-Fluoro-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide chemical structure, C20H22FN3O2, CAS 839688-18-5
3-Fluoro-N-[4-(4-propanoylpiperazin-1-yl)phenyl]benzamide
CAS 839688-18-5C20H22FN3O2
4-Cyano-2-fluoro-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide chemical structure, C19H19FN4O, CAS 839690-29-8
4-Cyano-2-fluoro-N-[4-(4-methylpiperazin-1-yl)phenyl]benzamide
CAS 839690-29-8C19H19FN4O
N-[3-Chloro-4-(4-methylpiperazin-1-yl)phenyl]-2-methylbenzamide chemical structure, C19H22ClN3O, CAS 839695-72-6
N-[3-Chloro-4-(4-methylpiperazin-1-yl)phenyl]-2-methylbenzamide
CAS 839695-72-6C19H22ClN3O
N-[4-(4-Butanoylpiperazin-1-yl)-3-chlorophenyl]-3,4,5-trimethoxybenzamide chemical structure, C24H30ClN3O5, CAS 906208-97-7
N-[4-(4-Butanoylpiperazin-1-yl)-3-chlorophenyl]-3,4,5-trimethoxybenzamide
CAS 906208-97-7C24H30ClN3O5
N-[3-Chloro-4-(4-methylpiperazin-1-yl)phenyl]-3,4-dimethylbenzamide chemical structure, C20H24ClN3O, CAS 842117-20-8
N-[3-Chloro-4-(4-methylpiperazin-1-yl)phenyl]-3,4-dimethylbenzamide
CAS 842117-20-8C20H24ClN3O
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-4-ethylbenzamide chemical structure, C21H25N3O2, CAS 900764-55-8
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-4-ethylbenzamide
CAS 900764-55-8C21H25N3O2
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-4-fluorobenzamide chemical structure, C20H21ClFN3O2, CAS 876896-56-9
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-4-fluorobenzamide
CAS 876896-56-9C20H21ClFN3O2
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-3-fluorobenzamide chemical structure, C20H21ClFN3O2, CAS 876896-91-2
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-3-fluorobenzamide
CAS 876896-91-2C20H21ClFN3O2
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-3-methylbenzamide chemical structure, C21H24ClN3O2, CAS 876896-76-3
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-3-methylbenzamide
CAS 876896-76-3C21H24ClN3O2
N-[4-(4-Acetylpiperazin-1-yl)-3-chlorophenyl]-4-methoxybenzamide chemical structure, C20H22ClN3O3, CAS 876898-74-7
N-[4-(4-Acetylpiperazin-1-yl)-3-chlorophenyl]-4-methoxybenzamide
CAS 876898-74-7C20H22ClN3O3
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-2-fluorobenzamide chemical structure, C20H21ClFN3O2, CAS 876896-86-5
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-2-fluorobenzamide
CAS 876896-86-5C20H21ClFN3O2
N-[4-(4-Acetylpiperazin-1-yl)-3-chlorophenyl]-3,5-dimethoxybenzamide chemical structure, C21H24ClN3O4, CAS 876885-78-8
N-[4-(4-Acetylpiperazin-1-yl)-3-chlorophenyl]-3,5-dimethoxybenzamide
CAS 876885-78-8C21H24ClN3O4
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-4-methylbenzamide chemical structure, C21H24ClN3O2, CAS 876896-36-5
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]-4-methylbenzamide
CAS 876896-36-5C21H24ClN3O2
N-[4-(4-Acetylpiperazin-1-yl)-3-chlorophenyl]-4-fluorobenzamide chemical structure, C19H19ClFN3O2, CAS 876898-86-1
N-[4-(4-Acetylpiperazin-1-yl)-3-chlorophenyl]-4-fluorobenzamide
CAS 876898-86-1C19H19ClFN3O2