CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 22 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
6
With full pages
1
Scaffold SMILES

O=C(Cc1ccccc1)Nc1ccc(-c2cccnc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)Nc1ccc(-c2cccnc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Orb2566139 chemical structure, C24H24F2N4O3, CAS 2247396-91-2
Orb2566139
CAS 2247396-91-2C24H24F2N4O3
Perk-IN-5 chemical structure, C25H26F2N4O3, CAS 2616821-91-9
Perk-IN-5
CAS 2616821-91-9C25H26F2N4O3
(S)-Perk-IN-5 chemical structure, C25H26F2N4O3, CAS 2616821-92-0
(S)-Perk-IN-5
CAS 2616821-92-0C25H26F2N4O3
HC-5404 Fumaricacid chemical structure, C28H28F2N4O7, CAS 3034479-99-4
HC-5404 Fumaricacid
CAS 3034479-99-4C28H28F2N4O7
(R)-2-Amino-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenyl)-N-isopropylnicotinamide hemifumarate chemical structure, C52H52F4N8O10
(R)-2-Amino-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenyl)-N-isopropylnicotinamide hemifumarate
C52H52F4N8O10
2-Amino-5-[4-[[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-2-methylphenyl]-N-propan-2-ylpyridine-3-carboxamide, (E)-but-2-enedioic acid, methane chemical structure, C29H32F2N4O7
2-Amino-5-[4-[[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-2-methylphenyl]-N-propan-2-ylpyridine-3-carboxamide, (E)-but-2-enedioic acid, methane
C29H32F2N4O7