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Murcko scaffold

1-(Benzenesulfonyl)-4-cinnamyl-piperazine scaffold

18 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 24
Chemicals: 18
With full pages: 3

Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCN(CC=Cc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1-(Benzenesulfonyl)-4-cinnamyl-piperazine page

Murcko scaffold O=S(=O)(c1ccccc1)N1CCN(CC=Cc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

4-(3-Phenylprop-2-enyl)-1-(phenylsulfonyl)piperazine chemical structure, C19H22N2O2S, CAS 325779-72-4

4-(3-Phenylprop-2-enyl)-1-(phenylsulfonyl)piperazine

CAS 325779-72-4C₁₉H₂₂N₂O₂S

1,4-Dichloro-2-((4-(3-phenylprop-2-enyl)piperazinyl)sulfonyl)benzene chemical structure, C19H20Cl2N2O2S, CAS 346692-11-3

1,4-Dichloro-2-((4-(3-phenylprop-2-enyl)piperazinyl)sulfonyl)benzene

CAS 346692-11-3C₁₉H₂₀Cl₂N₂O₂S

1-(4-Bromo-benzenesulfonyl)-4-(3-phenyl-allyl)-piperazine chemical structure, C19H21BrN2O2S, CAS 289628-40-6

1-(4-Bromo-benzenesulfonyl)-4-(3-phenyl-allyl)-piperazine

CAS 289628-40-6C₁₉H₂₁BrN₂O₂S

1-Cinnamyl-4-[(4-fluorophenyl)sulfonyl]piperazine chemical structure, C19H21FN2O2S, CAS 346692-08-8

1-Cinnamyl-4-[(4-fluorophenyl)sulfonyl]piperazine

CAS 346692-08-8C₁₉H₂₁FN₂O₂S

1-[(E)-3-Phenylprop-2-enyl]-4-(2,4,6-trimethylphenyl)sulfonylpiperazine chemical structure, C22H28N2O2S, CAS 346691-89-2

1-[(E)-3-Phenylprop-2-enyl]-4-(2,4,6-trimethylphenyl)sulfonylpiperazine

CAS 346691-89-2C₂₂H₂₈N₂O₂S

4-Chloro-1-((4-(3-phenylprop-2-enyl)piperazinyl)sulfonyl)benzene chemical structure, C19H21ClN2O2S, CAS 1049983-71-2

4-Chloro-1-((4-(3-phenylprop-2-enyl)piperazinyl)sulfonyl)benzene

CAS 1049983-71-2C₁₉H₂₁ClN₂O₂S

AC1Lllzn chemical structure, C19H21ClN2O2S, CAS 5256-98-4

CAS 5256-98-4C₁₉H₂₁ClN₂O₂S

4-[(4-Cinnamyl-1-piperazinyl)sulfonyl]phenyl methyl ether chemical structure, C20H24N2O3S, CAS 346691-65-4

4-[(4-Cinnamyl-1-piperazinyl)sulfonyl]phenyl methyl ether

CAS 346691-65-4C₂₀H₂₄N₂O₃S

1-(4-Iodophenyl)sulfonyl-4-[(E)-3-phenylprop-2-enyl]piperazine chemical structure, C19H21IN2O2S, CAS 433975-04-3

1-(4-Iodophenyl)sulfonyl-4-[(E)-3-phenylprop-2-enyl]piperazine

CAS 433975-04-3C₁₉H₂₁IN₂O₂S

1-Cinnamyl-4-tosylpiperazine chemical structure, C20H24N2O2S, CAS 1006613-62-2

1-Cinnamyl-4-tosylpiperazine

CAS 1006613-62-2C₂₀H₂₄N₂O₂S

1-(4-Nitrophenyl)sulfonyl-4-[(E)-3-phenylprop-2-enyl]piperazine chemical structure, C19H21N3O4S, CAS 1637562-04-9

1-(4-Nitrophenyl)sulfonyl-4-[(E)-3-phenylprop-2-enyl]piperazine

CAS 1637562-04-9C₁₉H₂₁N₃O₄S

1-[(E)-3-Phenylprop-2-enyl]-4-[2,4,6-tri(propan-2-yl)phenyl]sulfonylpiperazine chemical structure, C28H40N2O2S, CAS 352536-44-8

1-[(E)-3-Phenylprop-2-enyl]-4-[2,4,6-tri(propan-2-yl)phenyl]sulfonylpiperazine

CAS 352536-44-8C₂₈H₄₀N₂O₂S

1-(3,4-Difluorophenyl)sulfonyl-4-[(E)-3-phenylprop-2-enyl]piperazine chemical structure, C19H20F2N2O2S, CAS 618396-41-1

1-(3,4-Difluorophenyl)sulfonyl-4-[(E)-3-phenylprop-2-enyl]piperazine

CAS 618396-41-1C₁₉H₂₀F₂N₂O₂S

1-(Benzenesulfonyl)-4-cinnamyl-piperazine chemical structure, C19H22N2O2S, CAS 5264-21-1

1-(Benzenesulfonyl)-4-cinnamyl-piperazine

CAS 5264-21-1C₁₉H₂₂N₂O₂S

1-[(4-Ethylphenyl)sulfonyl]-4-(3-phenyl-2-propen-1-yl)piperazine chemical structure, C21H26N2O2S, CAS 325779-73-5

1-[(4-Ethylphenyl)sulfonyl]-4-(3-phenyl-2-propen-1-yl)piperazine

CAS 325779-73-5C₂₁H₂₆N₂O₂S

1-(4-Methyl-3-nitrophenyl)sulfonyl-4-[(E)-3-phenylprop-2-enyl]piperazine chemical structure, C20H23N3O4S, CAS 5354-74-5

1-(4-Methyl-3-nitrophenyl)sulfonyl-4-[(E)-3-phenylprop-2-enyl]piperazine

CAS 5354-74-5C₂₀H₂₃N₃O₄S

1-Cinnamyl-4-((4-methoxy-3-nitrophenyl)sulfonyl)piperazine chemical structure, C20H23N3O5S, CAS 325694-71-1

1-Cinnamyl-4-((4-methoxy-3-nitrophenyl)sulfonyl)piperazine

CAS 325694-71-1C₂₀H₂₃N₃O₅S

1-(4-Chloro-2-nitrophenyl)sulfonyl-4-[(E)-3-phenylprop-2-enyl]piperazine chemical structure, C19H20ClN3O4S, CAS 1025588-81-1

1-(4-Chloro-2-nitrophenyl)sulfonyl-4-[(E)-3-phenylprop-2-enyl]piperazine

CAS 1025588-81-1C₁₉H₂₀ClN₃O₄S