CompoundList
Sign in
Murcko scaffold

1-Phenylpiperazine scaffold

6,403 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
6,403
With full pages
595
Scaffold SMILES

c1ccc(N2CCNCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenylpiperazine page
Murcko scaffold c1ccc(N2CCNCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,201 to 1,248 of 6,403 chemicals

4-Mesityl-N,N-dimethyl-1-piperazinesulfonamide chemical structure, C15H25N3O2S, CAS 825608-18-2
4-Mesityl-N,N-dimethyl-1-piperazinesulfonamide
CAS 825608-18-2C15H25N3O2S
Methyl 4-(4-acetylpiperazin-1-yl)-3-aminobenzoate chemical structure, C14H19N3O3, CAS 767316-73-4
Methyl 4-(4-acetylpiperazin-1-yl)-3-aminobenzoate
CAS 767316-73-4C14H19N3O3
Methyl 3-[(2,2-dimethylpropanoyl)amino]-4-(4-ethyl-1-piperazinyl)benzoate chemical structure, C19H29N3O3, CAS 792938-66-0
Methyl 3-[(2,2-dimethylpropanoyl)amino]-4-(4-ethyl-1-piperazinyl)benzoate
CAS 792938-66-0C19H29N3O3
[5-Chloro-2-(4-isobutyrylpiperazin-1-yl)phenyl]amine chemical structure, C14H20ClN3O, CAS 879590-31-5
[5-Chloro-2-(4-isobutyrylpiperazin-1-yl)phenyl]amine
CAS 879590-31-5C14H20ClN3O
1-[4-(2-Amino-4-chlorophenyl)piperazin-1-yl]-3-methylbutan-1-one chemical structure, C15H22ClN3O, CAS 879590-35-9
1-[4-(2-Amino-4-chlorophenyl)piperazin-1-yl]-3-methylbutan-1-one
CAS 879590-35-9C15H22ClN3O
1-[4-(2-Amino-4-chlorophenyl)piperazin-1-yl]-2,2,2-trifluoroethanone chemical structure, C12H13ClF3N3O, CAS 879590-39-3
1-[4-(2-Amino-4-chlorophenyl)piperazin-1-yl]-2,2,2-trifluoroethanone
CAS 879590-39-3C12H13ClF3N3O
Ethyl 3-amino-4-(4-ethylpiperazin-1-yl)benzoate chemical structure, C15H23N3O2, CAS 792946-71-5
Ethyl 3-amino-4-(4-ethylpiperazin-1-yl)benzoate
CAS 792946-71-5C15H23N3O2
2-[4-(2-Methoxyphenyl)piperazin-1-yl]-2-methylpropan-1-amine chemical structure, C15H25N3O, CAS 879644-22-1
2-[4-(2-Methoxyphenyl)piperazin-1-yl]-2-methylpropan-1-amine
CAS 879644-22-1C15H25N3O
Ethyl 4-(2-nitrophenyl)piperazine-1-carboxylate chemical structure, C13H17N3O4, CAS 1001578-58-0
Ethyl 4-(2-nitrophenyl)piperazine-1-carboxylate
CAS 1001578-58-0C13H17N3O4
Ethyl 4-(4-amino-2-chlorophenyl)piperazine-1-carboxylate chemical structure, C13H18ClN3O2, CAS 864932-54-7
Ethyl 4-(4-amino-2-chlorophenyl)piperazine-1-carboxylate
CAS 864932-54-7C13H18ClN3O2
(E)-N-Butyl-2-cyano-3-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acrylamide chemical structure, C19H23F3N4O, CAS 885180-38-1
(E)-N-Butyl-2-cyano-3-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acrylamide
CAS 885180-38-1C19H23F3N4O
N-{2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl}acetamide chemical structure, C15H23N3O2, CAS 184951-34-6
N-{2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl}acetamide
CAS 184951-34-6C15H23N3O2
1-Piperazinepropanesulfonic acid, 4-phenyl- chemical structure, C13H20N2O3S, CAS 116275-18-4
1-Piperazinepropanesulfonic acid, 4-phenyl-
CAS 116275-18-4C13H20N2O3S
1-(4-Bromo-2-nitrophenyl)-4-methylpiperazine chemical structure, C11H14BrN3O2, CAS 1304356-49-7
1-(4-Bromo-2-nitrophenyl)-4-methylpiperazine
CAS 1304356-49-7C11H14BrN3O2
1-(4-(4-Bromo-2-nitrophenyl)piperazin-1-yl)ethanone chemical structure, C12H14BrN3O3, CAS 923140-91-4
1-(4-(4-Bromo-2-nitrophenyl)piperazin-1-yl)ethanone
CAS 923140-91-4C12H14BrN3O3
4-(4-Nitrophenyl)-1-piperazineacetic acid 1,1-dimethylethyl ester chemical structure, C16H23N3O4, CAS 1324530-12-2
4-(4-Nitrophenyl)-1-piperazineacetic acid 1,1-dimethylethyl ester
CAS 1324530-12-2C16H23N3O4
2-[4-(4-Acetylphenyl)piperazin-1-yl]-N-(1-cyano-1-methylethyl)-N-methylacetamide chemical structure, C19H26N4O2, CAS 1223236-49-4
2-[4-(4-Acetylphenyl)piperazin-1-yl]-N-(1-cyano-1-methylethyl)-N-methylacetamide
CAS 1223236-49-4C19H26N4O2
N-[5-Chloro-2-(4-propanoylpiperazin-1-yl)phenyl]-2,2,2-trifluoroacetamide chemical structure, C15H17ClF3N3O2, CAS 895068-46-9
N-[5-Chloro-2-(4-propanoylpiperazin-1-yl)phenyl]-2,2,2-trifluoroacetamide
CAS 895068-46-9C15H17ClF3N3O2
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]pentanamide chemical structure, C20H31N3O2, CAS 892711-45-4
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]pentanamide
CAS 892711-45-4C20H31N3O2
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-2,2-dimethylpropanamide chemical structure, C20H31N3O2, CAS 895076-80-9
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]-2,2-dimethylpropanamide
CAS 895076-80-9C20H31N3O2
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]acetamide chemical structure, C17H25N3O2, CAS 895082-23-2
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]acetamide
CAS 895082-23-2C17H25N3O2
N-[4-[4-(3-Methylbutanoyl)piperazin-1-yl]phenyl]butanamide chemical structure, C19H29N3O2, CAS 895080-12-3
N-[4-[4-(3-Methylbutanoyl)piperazin-1-yl]phenyl]butanamide
CAS 895080-12-3C19H29N3O2
3-Methyl-N-[4-[4-(3-methylbutanoyl)piperazin-1-yl]phenyl]butanamide chemical structure, C20H31N3O2, CAS 895080-76-9
3-Methyl-N-[4-[4-(3-methylbutanoyl)piperazin-1-yl]phenyl]butanamide
CAS 895080-76-9C20H31N3O2
N-[4-[4-(3-Methylbutanoyl)piperazin-1-yl]phenyl]acetamide chemical structure, C17H25N3O2, CAS 895087-10-2
N-[4-[4-(3-Methylbutanoyl)piperazin-1-yl]phenyl]acetamide
CAS 895087-10-2C17H25N3O2