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Murcko scaffold

Ring system with 3 rings and 21 atoms

32 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
32
With full pages
5
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCC(N2CCCCC2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1CCC(N2CCCCC2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

1-(4-Methoxyphenyl)sulfonyl-4-piperidin-1-ylpiperidine chemical structure, C17H26N2O3S, CAS 431996-69-9
1-(4-Methoxyphenyl)sulfonyl-4-piperidin-1-ylpiperidine
CAS 431996-69-9C17H26N2O3S
1-(4-Methylphenyl)sulfonyl-4-piperidin-1-ylpiperidine chemical structure, C17H26N2O2S, CAS 431923-11-4
1-(4-Methylphenyl)sulfonyl-4-piperidin-1-ylpiperidine
CAS 431923-11-4C17H26N2O2S
1-[1-(4-Fluorophenyl)sulfonylpiperidin-4-yl]-4-methylpiperidine chemical structure, C17H25FN2O2S, CAS 675151-61-8
1-[1-(4-Fluorophenyl)sulfonylpiperidin-4-yl]-4-methylpiperidine
CAS 675151-61-8C17H25FN2O2S
1-(4-Chlorophenyl)sulfonyl-4-piperidin-1-ylpiperidine chemical structure, C16H23ClN2O2S, CAS 675153-25-0
1-(4-Chlorophenyl)sulfonyl-4-piperidin-1-ylpiperidine
CAS 675153-25-0C16H23ClN2O2S
1'-[(4-Methylphenyl)sulfonyl][1,4'-bipiperidine]-4'-carboxamide chemical structure, C18H27N3O3S, CAS 681850-23-7
1'-[(4-Methylphenyl)sulfonyl][1,4'-bipiperidine]-4'-carboxamide
CAS 681850-23-7C18H27N3O3S
1-(4-Chlorophenyl)sulfonyl-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C17H24ClN3O3S, CAS 681850-22-6
1-(4-Chlorophenyl)sulfonyl-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 681850-22-6C17H24ClN3O3S
1'-[(4-Methoxyphenyl)sulfonyl]-1,4'-bipiperidine-4'-carboxamide chemical structure, C18H27N3O4S, CAS 681850-35-1
1'-[(4-Methoxyphenyl)sulfonyl]-1,4'-bipiperidine-4'-carboxamide
CAS 681850-35-1C18H27N3O4S
1-(Benzenesulfonyl)-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C17H25N3O3S, CAS 681851-73-0
1-(Benzenesulfonyl)-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 681851-73-0C17H25N3O3S
N-[4-[4-(4-Methylpiperidin-1-yl)piperidin-1-yl]sulfonylphenyl]acetamide chemical structure, C19H29N3O3S, CAS 792926-87-5
N-[4-[4-(4-Methylpiperidin-1-yl)piperidin-1-yl]sulfonylphenyl]acetamide
CAS 792926-87-5C19H29N3O3S
Tasin-1 chemical structure, C18H28N2O3S, CAS 792927-06-1
Tasin-1
CAS 792927-06-1C18H28N2O3S
1'-(4-Bromobenzenesulfonyl)-[1,4'-bipiperidine]-4'-carboxamide chemical structure, C17H24BrN3O3S, CAS 866017-84-7
1'-(4-Bromobenzenesulfonyl)-[1,4'-bipiperidine]-4'-carboxamide
CAS 866017-84-7C17H24BrN3O3S
1-(4-tert-Butylphenyl)sulfonyl-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C21H33N3O3S, CAS 727673-11-2
1-(4-tert-Butylphenyl)sulfonyl-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 727673-11-2C21H33N3O3S
1-[1-(4-Fluorophenyl)sulfonylpiperidin-4-yl]-3-methylpiperidine chemical structure, C17H25FN2O2S, CAS 431927-84-3
1-[1-(4-Fluorophenyl)sulfonylpiperidin-4-yl]-3-methylpiperidine
CAS 431927-84-3C17H25FN2O2S
1-[1-(4-Chlorophenyl)sulfonylpiperidin-4-yl]-3,5-dimethylpiperidine chemical structure, C18H27ClN2O2S, CAS 675152-30-4
1-[1-(4-Chlorophenyl)sulfonylpiperidin-4-yl]-3,5-dimethylpiperidine
CAS 675152-30-4C18H27ClN2O2S
4-Methyl-1-[1-(4-methylphenyl)sulfonylpiperidin-4-yl]piperidine chemical structure, C18H28N2O2S, CAS 792927-02-7
4-Methyl-1-[1-(4-methylphenyl)sulfonylpiperidin-4-yl]piperidine
CAS 792927-02-7C18H28N2O2S
1-[1-(Benzenesulfonyl)piperidin-4-yl]-3-methylpiperidine chemical structure, C17H26N2O2S, CAS 431994-93-3
1-[1-(Benzenesulfonyl)piperidin-4-yl]-3-methylpiperidine
CAS 431994-93-3C17H26N2O2S
1-[(2,4-Dimethylphenyl)sulfonyl]-4-piperidylpiperidine-4-carboxamide chemical structure, C19H29N3O3S, CAS 925199-89-9
1-[(2,4-Dimethylphenyl)sulfonyl]-4-piperidylpiperidine-4-carboxamide
CAS 925199-89-9C19H29N3O3S
1-[(2,5-Dimethylphenyl)sulfonyl]-4-piperidylpiperidine-4-carboxamide chemical structure, C19H29N3O3S, CAS 925046-56-6
1-[(2,5-Dimethylphenyl)sulfonyl]-4-piperidylpiperidine-4-carboxamide
CAS 925046-56-6C19H29N3O3S
1-[(2-Methylphenyl)sulfonyl]-4-piperidylpiperidine-4-carboxamide chemical structure, C18H27N3O3S, CAS 925046-58-8
1-[(2-Methylphenyl)sulfonyl]-4-piperidylpiperidine-4-carboxamide
CAS 925046-58-8C18H27N3O3S
1-(3-Chloro-4-fluorophenyl)sulfonyl-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C17H23ClFN3O3S, CAS 925199-93-5
1-(3-Chloro-4-fluorophenyl)sulfonyl-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 925199-93-5C17H23ClFN3O3S
6-Amino-3-chloro-2-(4-piperidin-1-ylpiperidin-1-yl)sulfonylphenol chemical structure, C16H24ClN3O3S, CAS 444045-59-4
6-Amino-3-chloro-2-(4-piperidin-1-ylpiperidin-1-yl)sulfonylphenol
CAS 444045-59-4C16H24ClN3O3S
1'-(Benzenesulfonyl)-4-methoxy-1,4'-bipiperidine chemical structure, C17H26N2O3S, CAS 1705062-16-3
1'-(Benzenesulfonyl)-4-methoxy-1,4'-bipiperidine
CAS 1705062-16-3C17H26N2O3S
1'-(4-Fluoro-2-methylbenzenesulfonyl)-4-methoxy-1,4'-bipiperidine chemical structure, C18H27FN2O3S, CAS 1705093-23-7
1'-(4-Fluoro-2-methylbenzenesulfonyl)-4-methoxy-1,4'-bipiperidine
CAS 1705093-23-7C18H27FN2O3S
1'-(4-Fluoro-3-methylbenzenesulfonyl)-4-methoxy-1,4'-bipiperidine chemical structure, C18H27FN2O3S, CAS 1705309-33-6
1'-(4-Fluoro-3-methylbenzenesulfonyl)-4-methoxy-1,4'-bipiperidine
CAS 1705309-33-6C18H27FN2O3S