CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

166 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
166
With full pages
15
Scaffold SMILES

O=C1C(=Cc2ccccc2)C=NN1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C(=Cc2ccccc2)C=NN1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 166 chemicals

(4E)-2-(3,4-Dichlorophenyl)-4-[4-(dimethylamino)benzylidene]-5-methyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C19H17Cl2N3O, CAS 329200-71-7
(4E)-2-(3,4-Dichlorophenyl)-4-[4-(dimethylamino)benzylidene]-5-methyl-2,4-dihydro-3H-pyrazol-3-one
CAS 329200-71-7C19H17Cl2N3O
(4E)-4-(3-Bromo-4-methoxybenzylidene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C18H15BrN2O2, CAS 292160-97-5
(4E)-4-(3-Bromo-4-methoxybenzylidene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
CAS 292160-97-5C18H15BrN2O2
(4E)-4-[(4-Ethoxy-3-methoxyphenyl)methylidene]-5-methyl-2-phenylpyrazol-3-one chemical structure, C20H20N2O3, CAS 292052-01-8
(4E)-4-[(4-Ethoxy-3-methoxyphenyl)methylidene]-5-methyl-2-phenylpyrazol-3-one
CAS 292052-01-8C20H20N2O3
2-Chloro-5-[(4Z)-4-(2,5-dimethoxybenzylidene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid chemical structure, C20H17ClN2O5, CAS 329199-85-1
2-Chloro-5-[(4Z)-4-(2,5-dimethoxybenzylidene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid
CAS 329199-85-1C20H17ClN2O5
2-Chloro-5-[(4Z)-4-(4-methoxybenzylidene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid chemical structure, C19H15ClN2O4, CAS 329199-78-2
2-Chloro-5-[(4Z)-4-(4-methoxybenzylidene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid
CAS 329199-78-2C19H15ClN2O4
2-Chloro-5-[(4E)-4-[(2-fluorophenyl)methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid chemical structure, C18H12ClFN2O3, CAS 312524-16-6
2-Chloro-5-[(4E)-4-[(2-fluorophenyl)methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid
CAS 312524-16-6C18H12ClFN2O3
2-Chloro-5-[(4Z)-4-(4-chlorobenzylidene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid chemical structure, C18H12Cl2N2O3, CAS 312706-46-0
2-Chloro-5-[(4Z)-4-(4-chlorobenzylidene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid
CAS 312706-46-0C18H12Cl2N2O3
5-[(4Z)-4-Benzylidene-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]-2-chlorobenzoic acid chemical structure, C18H13ClN2O3, CAS 312537-78-3
5-[(4Z)-4-Benzylidene-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]-2-chlorobenzoic acid
CAS 312537-78-3C18H13ClN2O3
(4E)-4-[(4-Bromophenyl)methylidene]-2-(3,4-dichlorophenyl)-5-methylpyrazol-3-one chemical structure, C17H11BrCl2N2O, CAS 328075-44-1
(4E)-4-[(4-Bromophenyl)methylidene]-2-(3,4-dichlorophenyl)-5-methylpyrazol-3-one
CAS 328075-44-1C17H11BrCl2N2O
(4E)-2-(3,4-Dichlorophenyl)-4-[(2-methoxyphenyl)methylidene]-5-methylpyrazol-3-one chemical structure, C18H14Cl2N2O2, CAS 5581-85-1
(4E)-2-(3,4-Dichlorophenyl)-4-[(2-methoxyphenyl)methylidene]-5-methylpyrazol-3-one
CAS 5581-85-1C18H14Cl2N2O2
2-(3,4-Dichlorophenyl)-4-(3-iodobenzylidene)-5-methyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C17H11Cl2IN2O, CAS 353780-72-0
2-(3,4-Dichlorophenyl)-4-(3-iodobenzylidene)-5-methyl-2,4-dihydro-3H-pyrazol-3-one
CAS 353780-72-0C17H11Cl2IN2O
4-[(4E)-3-Methyl-5-oxo-4-[(3,4,5-trimethoxyphenyl)methylidene]pyrazol-1-yl]benzoic acid chemical structure, C21H20N2O6, CAS 5838-12-0
4-[(4E)-3-Methyl-5-oxo-4-[(3,4,5-trimethoxyphenyl)methylidene]pyrazol-1-yl]benzoic acid
CAS 5838-12-0C21H20N2O6
4-[(4Z)-4-[(2,5-Dimethoxyphenyl)methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid chemical structure, C20H18N2O5, CAS 5843-63-0
4-[(4Z)-4-[(2,5-Dimethoxyphenyl)methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid
CAS 5843-63-0C20H18N2O5
(4E)-2-(3-Bromophenyl)-4-[(2,4-dimethoxyphenyl)methylidene]-5-methylpyrazol-3-one chemical structure, C19H17BrN2O3, CAS 5109-08-0
(4E)-2-(3-Bromophenyl)-4-[(2,4-dimethoxyphenyl)methylidene]-5-methylpyrazol-3-one
CAS 5109-08-0C19H17BrN2O3
(4Z)-4-(4-Chlorobenzylidene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one chemical structure, C17H13ClN2O, CAS 39143-10-7
(4Z)-4-(4-Chlorobenzylidene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
CAS 39143-10-7C17H13ClN2O
[4-[(E)-[1-(3,4-Dichlorophenyl)-3-methyl-5-oxopyrazol-4-ylidene]methyl]-2-methoxyphenyl] acetate chemical structure, C20H16Cl2N2O4, CAS 1321763-90-9
[4-[(E)-[1-(3,4-Dichlorophenyl)-3-methyl-5-oxopyrazol-4-ylidene]methyl]-2-methoxyphenyl] acetate
CAS 1321763-90-9C20H16Cl2N2O4
(4E)-4-[(2-Chlorophenyl)methylidene]-5-methyl-2-(4-nitrophenyl)pyrazol-3-one chemical structure, C17H12ClN3O3, CAS 5852-97-1
(4E)-4-[(2-Chlorophenyl)methylidene]-5-methyl-2-(4-nitrophenyl)pyrazol-3-one
CAS 5852-97-1C17H12ClN3O3
(4E)-2-(4-Nitrophenyl)-4-[(3-nitrophenyl)methylidene]-5-propylpyrazol-3-one chemical structure, C19H16N4O5, CAS 371215-27-9
(4E)-2-(4-Nitrophenyl)-4-[(3-nitrophenyl)methylidene]-5-propylpyrazol-3-one
CAS 371215-27-9C19H16N4O5
(Z)-2-Chloro-5-(4-(4-ethylbenzylidene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid chemical structure, C20H17ClN2O3, CAS 355368-97-7
(Z)-2-Chloro-5-(4-(4-ethylbenzylidene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
CAS 355368-97-7C20H17ClN2O3
3-[(4Z)-4-[(3-Bromophenyl)methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid chemical structure, C18H13BrN2O3, CAS 5998-99-2
3-[(4Z)-4-[(3-Bromophenyl)methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid
CAS 5998-99-2C18H13BrN2O3
4-[4-(4-Methoxybenzylidene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]benzenesulfonamide chemical structure, C18H17N3O4S, CAS 6034-28-2
4-[4-(4-Methoxybenzylidene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]benzenesulfonamide
CAS 6034-28-2C18H17N3O4S
4-[(4Z)-4-[(3-Methoxy-4-prop-2-enoxyphenyl)methylidene]-3-methyl-5-oxopyrazol-1-yl]benzenesulfonamide chemical structure, C21H21N3O5S, CAS 6034-29-3
4-[(4Z)-4-[(3-Methoxy-4-prop-2-enoxyphenyl)methylidene]-3-methyl-5-oxopyrazol-1-yl]benzenesulfonamide
CAS 6034-29-3C21H21N3O5S
4-[(4Z)-3-Methyl-4-[(4-methylphenyl)methylidene]-5-oxopyrazol-1-yl]benzenesulfonamide chemical structure, C18H17N3O3S, CAS 425390-48-3
4-[(4Z)-3-Methyl-4-[(4-methylphenyl)methylidene]-5-oxopyrazol-1-yl]benzenesulfonamide
CAS 425390-48-3C18H17N3O3S
4-[(4Z)-4-[(3-Methoxyphenyl)methylidene]-3-methyl-5-oxopyrazol-1-yl]benzenesulfonamide chemical structure, C18H17N3O4S, CAS 425390-81-4
4-[(4Z)-4-[(3-Methoxyphenyl)methylidene]-3-methyl-5-oxopyrazol-1-yl]benzenesulfonamide
CAS 425390-81-4C18H17N3O4S