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Murcko scaffold

Ring system with 3 rings and 18 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
16
With full pages
1
Scaffold SMILES

c1ccc(Nc2nc(-c3cccnc3)cs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2nc(-c3cccnc3)cs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

4-(4-Pyridin-3-yl-thiazol-2-ylamino)-benzoic acid chemical structure, C15H11N3O2S, CAS 315703-23-2
4-(4-Pyridin-3-yl-thiazol-2-ylamino)-benzoic acid
CAS 315703-23-2C15H11N3O2S
3-(4-Pyridin-3-yl-thiazol-2-ylamino)-benzoic acid chemical structure, C15H11N3O2S, CAS 315703-28-7
3-(4-Pyridin-3-yl-thiazol-2-ylamino)-benzoic acid
CAS 315703-28-7C15H11N3O2S
4-N-(4-Pyridin-3-yl-1,3-thiazol-2-yl)benzene-1,4-diamine chemical structure, C14H12N4S, CAS 315703-30-1
4-N-(4-Pyridin-3-yl-1,3-thiazol-2-yl)benzene-1,4-diamine
CAS 315703-30-1C14H12N4S
1-(4-{[4-(Pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)ethanone chemical structure, C16H13N3OS, CAS 708993-55-9
1-(4-{[4-(Pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)ethanone
CAS 708993-55-9C16H13N3OS
Bas 08770291 chemical structure, C15H13N3S, CAS 5833-82-9
Bas 08770291
CAS 5833-82-9C15H13N3S
N-(2,6-Dibromo-4-methoxyphenyl)-4-pyridin-3-yl-1,3-thiazol-2-amine, hydrobromide chemical structure, C15H12Br3N3OS, CAS 5931-61-3
N-(2,6-Dibromo-4-methoxyphenyl)-4-pyridin-3-yl-1,3-thiazol-2-amine, hydrobromide
CAS 5931-61-3C15H12Br3N3OS
4-(4-Pyridin-3-yl-thiazol-2-ylamino)-benzenesulfonamide chemical structure, C14H12N4O2S2, CAS 315703-36-7
4-(4-Pyridin-3-yl-thiazol-2-ylamino)-benzenesulfonamide
CAS 315703-36-7C14H12N4O2S2
2-Thiazolamine, 5-fluoro-4-(3-pyridinyl)-N-[3-(trifluoromethyl)phenyl]- chemical structure, C15H9F4N3S, CAS 499984-43-9
2-Thiazolamine, 5-fluoro-4-(3-pyridinyl)-N-[3-(trifluoromethyl)phenyl]-
CAS 499984-43-9C15H9F4N3S
5-Fluoro-N-(4-octyl-3-(trifluoromethyl)phenyl)-4-(pyridin-3-yl)thiazol-2-amine chemical structure, C23H25F4N3S, CAS 1076222-04-2
5-Fluoro-N-(4-octyl-3-(trifluoromethyl)phenyl)-4-(pyridin-3-yl)thiazol-2-amine
CAS 1076222-04-2C23H25F4N3S
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)-1,3-thiazol-2-amine chemical structure, C15H12N4O2S, CAS 1048007-94-8
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)-1,3-thiazol-2-amine
CAS 1048007-94-8C15H12N4O2S
6-Methyl-N1-(4-(pyridin-3-yl)thiazol-2-yl)benzene-1,3-diamine chemical structure, C15H14N4S, CAS 660837-08-1
6-Methyl-N1-(4-(pyridin-3-yl)thiazol-2-yl)benzene-1,3-diamine
CAS 660837-08-1C15H14N4S
N-(2-Methyl-5-nitrophenyl)-4-(3-pyridinyl)-2-thiazolamine hydrobromide chemical structure, C15H13BrN4O2S, CAS 1143459-81-7
N-(2-Methyl-5-nitrophenyl)-4-(3-pyridinyl)-2-thiazolamine hydrobromide
CAS 1143459-81-7C15H13BrN4O2S
4-Methyl-N3-(4-(pyridin-3-yl)-1,3-thiazol-2-yl)benzene-1,3-diamine dihydrochloride chemical structure, C15H16Cl2N4S, CAS 1143459-92-0
4-Methyl-N3-(4-(pyridin-3-yl)-1,3-thiazol-2-yl)benzene-1,3-diamine dihydrochloride
CAS 1143459-92-0C15H16Cl2N4S
tert-Butyl (4-methyl-3-((4-(pyridin-3-yl)thiazol-2-yl)amino)phenyl)carbamate chemical structure, C20H22N4O2S, CAS 660837-07-0
tert-Butyl (4-methyl-3-((4-(pyridin-3-yl)thiazol-2-yl)amino)phenyl)carbamate
CAS 660837-07-0C20H22N4O2S
4-(6-Chloropyridin-3-yl)-N-(4-fluorophenyl)-1,3-thiazol-2-amine hydrochloride chemical structure, C14H10Cl2FN3S, CAS 2694744-98-2
4-(6-Chloropyridin-3-yl)-N-(4-fluorophenyl)-1,3-thiazol-2-amine hydrochloride
CAS 2694744-98-2C14H10Cl2FN3S
4-(6-Chloropyridin-3-yl)-N-(4-fluorophenyl)thiazol-2-amine chemical structure, C14H9ClFN3S, CAS 2694744-97-1
4-(6-Chloropyridin-3-yl)-N-(4-fluorophenyl)thiazol-2-amine
CAS 2694744-97-1C14H9ClFN3S